SIRT1 inhibits gastric cancer proliferation and metastasis via STAT3/MMP‐13 signaling

2019 ◽  
Vol 234 (9) ◽  
pp. 15395-15406 ◽  
Author(s):  
Shu Zhang ◽  
Yang Yang ◽  
Shuling Huang ◽  
Chao Deng ◽  
Siqi Zhou ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Proliferation ◽  
Proliferation And Metastasis

HnRNPR/CCNB1/CENPF Axis Contributes to Gastric Cancer Proliferation and Metastasis

2019 ◽  
Author(s):  
Er-Bao Chen ◽  
Xuan Qin ◽  
Ke Peng ◽  
Qian Li ◽  
Cheng Tang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Proliferation ◽  
Proliferation And Metastasis

scholarly journals Long non‑coding RNA MIAT promotes gastric cancer proliferation and metastasis via modulating the miR‑331‑3p/RAB5B pathway

2020 ◽  
Vol 20 (6) ◽  
pp. 1-1
Author(s):  
Xiao-Mei Li ◽  
Yan-Yan Jiao ◽  
Bao-Hong Luan ◽  
Hong-Xia Wu ◽  
Rong-Rong Wang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Proliferation ◽  
Non Coding Rna ◽  
Proliferation And Metastasis ◽  
Long Non Coding Rna

Hsa_circ_0017639 expression promotes gastric cancer proliferation and metastasis by sponging miR-224-5p and upregulating USP3

Gene ◽  
2020 ◽  
Vol 750 ◽  
pp. 144753 ◽  
Author(s):  
Bojing Li ◽  
Mingming Jin ◽  
Fanfan Cao ◽  
Jie Li ◽  
Jian Wu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Proliferation ◽  
Proliferation And Metastasis

scholarly journals HnRNPR-CCNB1/CENPF axis contributes to gastric cancer proliferation and metastasis

Aging ◽  
2019 ◽  
Vol 11 (18) ◽  
pp. 7473-7491 ◽  
Author(s):  
Er-Bao Chen ◽  
Xuan Qin ◽  
Ke Peng ◽  
Qian Li ◽  
Cheng Tang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Proliferation ◽  
Proliferation And Metastasis

scholarly journals MicroRNA-653-5p Promotes Gastric Cancer Proliferation and Metastasis by Targeting the SOCS6-STAT3 Pathway

2021 ◽  
Vol 8 ◽  
Author(s):  
Zengliang Li ◽  
Hao Fan ◽  
Wangwang Chen ◽  
Jian Xiao ◽  
Xiang Ma ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Janus Kinase ◽  
Migration And Invasion ◽  
Cytokine Signaling ◽  
Cancer Proliferation ◽  
Stat3 Signaling ◽  
Stat3 Signaling Pathway ◽  
Proliferation And Metastasis

MicroRNAs (miRNAs) are emerging as significant regulators of the tumorigenesis of gastric cancer (GC), and may be effective biomarkers for diagnosis, prognosis, and therapeutic targeting for GC. In this study, miR-653-5p was found to be significantly upregulated in GC tissues, serum, and cell lines and was strongly associated with poor prognosis in patients with GC. Furthermore, miR-653-5p promoted GC cell proliferation and metastasis in vivo and in vitro. Suppressor of cytokine signaling 6 (SOCS6) was directly targeted by miR-653-5p, and SOCS6 attenuated miR-653-5p-mediated GC cell growth, migration, and invasion. In addition, SOCS6-mediated inactivation of the Janus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) signaling pathway was also reversed by the administration of miR-653-5p. The findings from this study support a novel regulatory axis between miR-653-5p, SOCS6, and JAK2/STAT3 that may be a target for diagnosis and therapeutic intervention for GC.

scholarly journals Downregulation of homeobox gene Barx2 increases gastric cancer proliferation and metastasis and predicts poor patient outcomes

Oncotarget ◽  
2016 ◽  
Vol 7 (37) ◽  
pp. 60593-60608 ◽  
Author(s):  
Yushuai Mi ◽  
Senlin Zhao ◽  
Chongzhi Zhou ◽  
Junyong Weng ◽  
Jikun Li ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Patient Outcomes ◽  
Homeobox Gene ◽  
Cancer Proliferation ◽  
Poor Patient ◽  
Proliferation And Metastasis

scholarly journals lnc RNA HOTAIR promotes gastric cancer proliferation and metastasis via targeting miR‐126 to active CXCR 4 and RhoA signaling pathway

2019 ◽  
Vol 8 (15) ◽  
pp. 6768-6779 ◽  
Author(s):  
Jun Xiao ◽  
Hao Lai ◽  
Sheng‐Hong Wei ◽  
Zai‐Sheng Ye ◽  
Fu‐Sheng Gong ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Signaling Pathway ◽  
Cancer Proliferation ◽  
Proliferation And Metastasis ◽  
Rhoa Signaling
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