Human trisomy 21 fibroblasts rescue methotrexate toxic effect after treatment with 5‐methyl‐tetrahydrofolate and 5‐formyl‐tetrahydrofolate

2019 ◽  
Vol 234 (9) ◽  
pp. 15010-15024 ◽  
Author(s):  
Lorenza Vitale ◽  
Valentina Serpieri ◽  
Mattia Lauriola ◽  
Allison Piovesan ◽  
Francesca Antonaros ◽  
...  
Keyword(s):  
Toxic Effect ◽  
Trisomy 21 ◽  
Methyl Tetrahydrofolate

Investigating miR-125b target gene Arid3a in trisomy 21-associated leukemogenesis

2020 ◽  
Author(s):  
K Weigert ◽  
O Alejo-Valle ◽  
M Labuhn ◽  
V Amstislavskiy ◽  
S Emmrich ◽  
...  
Keyword(s):  
Trisomy 21 ◽  
Target Gene

‘The Stuff of Slow Constitution’: Reading Down Syndrome for Race, Disability, and the Timing that Makes Them So

Somatechnics ◽  
2016 ◽  
Vol 6 (2) ◽  
pp. 235-248 ◽  
Author(s):  
Mel Y. Chen
Keyword(s):  
Down Syndrome ◽  
Trisomy 21 ◽  
Historical Perspective ◽  
Early History ◽  
Present Moment ◽  
History Of ◽  
Living Being

In this paper I would like to bring into historical perspective the interrelation of several notions such as race and disability, which at the present moment seem to risk, especially in the fixing language of diversity, being institutionalised as orthogonal in nature to one another rather than co-constitutive. I bring these notions into historical clarity primarily through the early history of what is today known as Down Syndrome or Trisomy 21, but in 1866 was given the name ‘mongoloid idiocy’ by English physician John Langdon Down. In order to examine the complexity of these notions, I explore the idea of ‘slow’ populations in development, the idea of a material(ist) constitution of a living being, the ‘fit’ or aptness of environmental biochemistries broadly construed, and, finally, the germinal interarticulation of race and disability – an ensemble that continues to commutatively enflesh each of these notions in their turn.

Evaluating The Potential Toxic Effect of Aflatoxin and Ochratoxin on Serum Biochemical Parameters in Coloured (Raja Ii) Broilers

2012 ◽  
Vol 3 (8) ◽  
pp. 215-217
Author(s):  
Dr Jayashree Pattar ◽  
◽  
Dr Shridhar,N.B Dr Shridhar,N.B ◽  
Dr Jagadeesh .S Sanganal ◽  
Dr M.L Satyanarayana Dr M.L Satyanarayana ◽  
...  
Keyword(s):  
Toxic Effect ◽  
Biochemical Parameters ◽  
Serum Biochemical Parameters ◽  
Serum Biochemical

INFLUENCE OF MINERAL SORBENTS ON GROWTH AND DEVELOPMENT OF HORDEUM VULGARE ON SOIL POLLUTED BY BENZ(A)PYRENE

2020 ◽  
Author(s):  
A.I. Barbashev ◽  
◽  
S.N. Sushkova ◽  
T.M. Minkina ◽  
T.S. Dudnikova ◽  
...  
Keyword(s):  
Hordeum Vulgare ◽  
Toxic Effect ◽  
Contaminated Soil ◽  
Growth And Development

The effect of diatomite and tripoli added into the soil artificially contaminated with benzo[a]pyrene was studied. A decrease in the toxic effect of BaP on barley plants was established when diatomite and tripoli were added as ameliorants to contaminated soil. The improvement of plants grown сharacteristics on soils contaminated with BaP with the addition of diatomite and tripoli was shown up to 2-4 times compare to contaminated samples.

Static and Dynamic Studies of Gasoline in View of its Octane Number and its Toxic Effect

2013 ◽  
Vol 12 (7) ◽  
pp. 451-459
Author(s):  
Ashraf Yehia El-Naggar ◽  
Mohamed A. Ebiad
Keyword(s):  
Toxic Effect ◽  
Aromatic Hydrocarbons ◽  
Octane Number ◽  
Liquid Fuel ◽  
Positive Impact ◽  
Hydrocarbon Composition ◽  
Different Temperatures ◽  
Different Seasons ◽  
The One ◽  
The Impact

Gasoline come primarily from petroleum cuts, it is the preferred liquid fuel in our lives. Two gasoline samples of octane numbers 91 and 95 from Saudi Arabia petrol stations were studied. This study was achieved at three different temperatures 20oC, 30oC and 50oC representing the change in temperatures of the different seasons of the year. Both the evaporated gases of light aromatic hydrocarbons (BTEX) of gasoline samples inside the tank were subjected to analyze qualitatively and quantitatively via capillary gas chromatography. The detailed hydrocarbon composition and the octane number of the studied gasoline samples were determined using detailed hydrocarbon analyzer. The idea of research is indicating the impact of light aromatic compounds in gasoline on the toxic effect of human and environment on the one hand, and on octane number of gasoline on the other hand. Although the value of octane number will be reduced but this will have a positive impact on the environment as a way to produce clean fuel.

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