Circulating MicroRNA and Long Noncoding RNA as Biomarkers of Cardiovascular Diseases

2015 ◽  
Vol 231 (4) ◽  
pp. 751-755 ◽  
Author(s):  
Qiang Shi ◽  
Xi Yang
Keyword(s):  
Cardiovascular Diseases ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Circulating Microrna

Implication of regulatory networks of long noncoding RNA/circular RNA-miRNA-mRNA in diabetic cardiovascular diseases

Epigenomics ◽  
2020 ◽  
Vol 12 (21) ◽  
pp. 1929-1947
Author(s):  
Wei Xiong ◽  
Mengran Yao ◽  
Yuqiao Yang ◽  
Yan Qu ◽  
Jinqiao Qian
Keyword(s):  
Diabetes Mellitus ◽  
Cardiovascular Diseases ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Regulatory Networks ◽  
Noncoding Rnas ◽  
Circular Rna ◽  
Competing Endogenous Rna ◽  
Prognostic Evaluation ◽  
Functional Roles

Diabetic cardiovascular diseases (DCVDs) are the most common complications of diabetes mellitus and are considered to be one of the most important threats to global health and an economic burden. Long noncoding RNA (lncRNA), circular RNA (circRNA), and miRNA are a novel group of noncoding RNAs that are involved in the regulation of various pathophysiological processes, including DCVDs. Interestingly, both lncRNA and circRNA can act as competing endogenous RNA of miRNA, thereby regulating the expression of the target mRNA by decoying or sponging the miRNA. In this review, we focus on the mechanistic, pathological and functional roles of lncRNA/circRNA-miRNA-mRNA networks in DCVDs and further discuss the potential implications for early detection, therapeutic intervention and prognostic evaluation.

Long noncoding RNA/circular noncoding RNA–miRNA–mRNA axes in cardiovascular diseases

Life Sciences ◽  
2019 ◽  
Vol 233 ◽  
pp. 116440 ◽  
Author(s):  
Ming Li ◽  
Liwei Duan ◽  
Yangxue Li ◽  
Bin Liu
Keyword(s):  
Cardiovascular Diseases ◽  
Long Noncoding Rna ◽  
Noncoding Rna
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