scholarly journals Essential role of maternal UCHL1 and UCHL3 in fertilization and preimplantation embryo development

2012 ◽  
Vol 227 (4) ◽  
pp. 1592-1603 ◽  
Author(s):  
Namdori R. Mtango ◽  
Miriam Sutovsky ◽  
Andrej Susor ◽  
Zhisheng Zhong ◽  
Keith E. Latham ◽  
...  
2020 ◽  
Vol 27 (12) ◽  
pp. 1181-1185
Author(s):  
Rossella Cannarella ◽  
Rosita A. Condorelli ◽  
Aldo E. Calogero ◽  
Sandro La Vignera

: The spermatozoon has classically been seen only as a paternal DNA transporter into the oocyte, thus underestimating the entire contribution of the male gamete to the embryo development. The advancement of the research supports that not only the sperm genome, but the entire sperm transcriptome and proteome carry crucial information for fertilization and embryo development. : Altogether, 6871 proteins have been reported in spermatozoa so far. Their functional analysis has recently addressed to the sperm proteome a role in fertilization, preimplantation embryo development and paternal epigenetic inheritance. Targeted analysis of human spermatozoa is warranted to compile an evidence-based list of sperm-carried molecular targets in infertile patients.


1996 ◽  
Vol 54 (6) ◽  
pp. 1420-1429 ◽  
Author(s):  
Pat Lonergan ◽  
Catherine Carolan ◽  
Anne Van Langendonckt ◽  
Isabelle Donnay ◽  
Hadj Khatir ◽  
...  

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