Epigenetically regulated clonal heritability of CTA expression profiles in human melanoma

2010 ◽  
pp. n/a-n/a ◽  
Author(s):  
Elisabetta Fratta ◽  
Luca Sigalotti ◽  
Francesca Colizzi ◽  
Alessia Covre ◽  
Hugues JMG Nicolay ◽  
...  
Keyword(s):  
Expression Profiles ◽  
Human Melanoma ◽  
Clonal Heritability

scholarly journals Gene expression profiles of human melanoma cells with different invasive potential reveal TSPAN8 as a novel mediator of invasion

2010 ◽  
Vol 104 (1) ◽  
pp. 155-165 ◽  
Author(s):  
O Berthier-Vergnes ◽  
M El Kharbili ◽  
A de la Fouchardière ◽  
T Pointecouteau ◽  
P Verrando ◽  
...  
Keyword(s):  
Gene Expression ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Invasive Potential ◽  
Human Melanoma Cells

scholarly journals Antitumor activity and expression profiles of genes induced by sulforaphane in human melanoma cells

2017 ◽  
Vol 57 (7) ◽  
pp. 2547-2569 ◽  
Author(s):  
Paola Arcidiacono ◽  
Francesco Ragonese ◽  
Anna Stabile ◽  
Alessandra Pistilli ◽  
Ekaterina Kuligina ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Expression Profiles ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Human Melanoma Cells

scholarly journals PO-159 Expression profiles of P53/P73 isoforms in human melanoma cell lines

2018 ◽  
Author(s):  
N Slade ◽  
N Hanžić ◽  
M Radić ◽  
P Ozretić ◽  
L Petrović ◽  
...  
Keyword(s):  
Cell Lines ◽  
Melanoma Cell ◽  
Expression Profiles ◽  
Human Melanoma ◽  
Human Melanoma Cell ◽  
Melanoma Cell Lines

93: Gene expression profiles of human melanoma cells with different invasive potential reveal TSPAN8 as a novel mediator of invasion

2010 ◽  
Vol 97 (1) ◽  
pp. S76
Author(s):  
Kharbili Manale El ◽  
Jérôme Lamartine ◽  
Arnaud de la Fouchardière ◽  
Thomas Pointecouteau ◽  
François Le Naour ◽  
...  
Keyword(s):  
Gene Expression ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Invasive Potential ◽  
Human Melanoma Cells

An Ultra-Structural Study of Human Melanoma in Vivo and Vitro

1976 ◽  
Vol 34 ◽  
pp. 258-259
Author(s):  
James R. Gaylor ◽  
Fredda Schafer ◽  
Robert E. Nordquist
Keyword(s):  
Endoplasmic Reticulum ◽  
Golgi Apparatus ◽  
Protein Aggregation ◽  
Structural Study ◽  
Human Melanoma ◽  
Protein Matrix ◽  
Early Form ◽  
Endoplasmic Reticulum Protein ◽  
Mitochondrial Origin

Several theories on the origin of the melanosome exist. These include the Golgi origin theory, in which a tyrosinase-rich protein is "packaged" by the Golgi apparatus, thus forming the early form of the melanosome. A second theory postulates a mitochondrial origin of melanosomes. Its author contends that the melanosome is a modified mitochondria which acquires melanin during its development. A third theory states that a pre-melanosome is formed in the smooth or rough endoplasmic reticulum. Protein aggregation is suggested by one author as a possible source of the melanosome. This fourth theory postulates that the melanosome originates when the protein products of several genetic loci aggregate in the cytoplasm of the melanocyte. It is this protein matrix on which the melanin is deposited. It was with these theories in mind that this project was undertaken.

Sequential detection of mRNA for the chemokine IL-8 and macrophages (F4/80) in human melanoma

1995 ◽  
Vol 53 ◽  
pp. 1008-1009
Author(s):  
C.D. Bucana ◽  
R. Sanchez ◽  
R. Singh ◽  
I.J. Fidler
Keyword(s):  
Tumor Cells ◽  
Nude Mice ◽  
Constitutive Expression ◽  
Metastatic Potential ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Angiogenic Factor ◽  
Infiltrating Cells ◽  
Immunoperoxidase Assay ◽  
Multifunctional Cytokine

The purpose of this study was to demonstrate by ISH the presence of IL-8 mRNA, and by immunohistochemistry (IHC) the presence of the chemokine IL-8 and the distribution of infiltrating macrophages in subcutaneous melanomas in the same tumor. IL-8 is a multifunctional cytokine produced by melanoma cells, activated macrophages and monocytes and it has been shown to be a growth and angiogenic factor for tumor cells. More recently it was shown that constitutive expression of IL-8 correlated directly with metastatic potential of human melanoma cells in nude mice. IL-8 content of a solid tumor as determined by Western blot analysis does not take into account the contribution of macrophages. Previous studies showed that murine tumors contain many infiltrating cells interspersed among tumor cells whereas human tumors growing in nude mice exhibit macrophages at the periphery or between tumor islands. In this study we demonstrate the expression of IL-8 and the distribution of macrophages by immunoperoxidase assay and IL-8 mRNA by ISH.

1327: Gene Expression Profiles in Benign Prostatic Hyperplasia

2004 ◽  
Vol 171 (4S) ◽  
pp. 349-350
Author(s):  
Gaelle Fromont ◽  
Michel Vidaud ◽  
Alain Latil ◽  
Guy Vallancien ◽  
Pierre Validire ◽  
...  
Keyword(s):  
Gene Expression ◽  
Benign Prostatic Hyperplasia ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Prostatic Hyperplasia
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