Alpha-1 adrenergic receptor transactivates signal transducer and activator of transcription-3 (Stat3) through activation of Src and epidermal growth factor receptor (EGFR) in hepatocytes

Chang Han; William C. Bowen; George K. Michalopoulos; Tong Wu

doi:10.1002/jcp.21420

Alpha-1 adrenergic receptor transactivates signal transducer and activator of transcription-3 (Stat3) through activation of Src and epidermal growth factor receptor (EGFR) in hepatocytes

Journal of Cellular Physiology ◽

10.1002/jcp.21420 ◽

2008 ◽

Vol 216 (2) ◽

pp. 486-497 ◽

Cited By ~ 24

Author(s):

Chang Han ◽

William C. Bowen ◽

George K. Michalopoulos ◽

Tong Wu

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Adrenergic Receptor ◽

Growth Factor Receptor ◽

Signal Transducer ◽

Epidermal Growth ◽

Transcription 3

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Intercellular contact augments epidermal growth factor receptor (EGFR) and signal transducer and activator of transcription 3 (STAT3)-activation which increases podoplanin-expression in order to promote squamous cell carcinoma motility

Cellular Signalling ◽

10.1016/j.cellsig.2012.12.004 ◽

2013 ◽

Vol 25 (4) ◽

pp. 760-765 ◽

Cited By ~ 8

Author(s):

Mizue Fujii ◽

Masaru Honma ◽

Hidetoshi Takahashi ◽

Akemi Ishida-Yamamoto ◽

Hajime Iizuka

Keyword(s):

Squamous Cell Carcinoma ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Intercellular Contact ◽

Signal Transducer ◽

Podoplanin Expression ◽

Epidermal Growth ◽

Transcription 3

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SCH66336, inhibitor of protein farnesylation, blocks signal transducer and activators of transcription 3 signaling in lung cancer and interacts with a small molecule inhibitor of epidermal growth factor receptor/human epidermal growth factor receptor 2

Anti-Cancer Drugs ◽

10.1097/cad.0b013e3282f1a908 ◽

2008 ◽

Vol 19 (1) ◽

pp. 9-16 ◽

Cited By ~ 12

Author(s):

Afshin Dowlati ◽

Amy Kluge ◽

David Nethery ◽

Balazs Halmos ◽

Jeffrey A. Kern

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Small Molecule ◽

Growth Factor Receptor ◽

Signal Transducer ◽

Molecule Inhibitor ◽

Epidermal Growth ◽

Transcription 3

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Epidermal Growth Factor Receptor Cooperates with Signal Transducer and Activator of Transcription 3 to Induce Epithelial-Mesenchymal Transition in Cancer Cells via Up-regulation of TWIST Gene Expression

Cancer Research ◽

10.1158/0008-5472.can-07-0575 ◽

2007 ◽

Vol 67 (19) ◽

pp. 9066-9076 ◽

Cited By ~ 430

Author(s):

Hui-Wen Lo ◽

Sheng-Chieh Hsu ◽

Weiya Xia ◽

Xinyu Cao ◽

Jin-Yuan Shih ◽

...

Keyword(s):

Gene Expression ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Epithelial Mesenchymal Transition ◽

Growth Factor Receptor ◽

Signal Transducer ◽

Mesenchymal Transition ◽

Epidermal Growth ◽

Transcription 3

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Combined Targeting of Epidermal Growth Factor Receptor, Signal Transducer and Activator of Transcription-3, and Bcl-XL Enhances Antitumor Effects in Squamous Cell Carcinoma of the Head and Neck

Molecular Pharmacology ◽

10.1124/mol.107.044636 ◽

2008 ◽

Vol 73 (6) ◽

pp. 1632-1642 ◽

Cited By ~ 53

Author(s):

Amanda L. Boehm ◽

Malabika Sen ◽

Raja Seethala ◽

William E. Gooding ◽

Maria Freilino ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Signal Transducer ◽

Antitumor Effects ◽

Receptor Signal ◽

Epidermal Growth ◽

Transcription 3

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Signal Transducer and Activator of Transcription 3 Is Required for the Oncogenic Effects of Non–Small-Cell Lung Cancer–Associated Mutations of the Epidermal Growth Factor Receptor

Cancer Research ◽

10.1158/0008-5472.can-05-3757 ◽

2006 ◽

Vol 66 (6) ◽

pp. 3162-3168 ◽

Cited By ~ 160

Author(s):

James V. Alvarez ◽

Heidi Greulich ◽

William R. Sellers ◽

Matthew Meyerson ◽

David A. Frank

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Small Cell ◽

Signal Transducer ◽

Small Cell Lung ◽

Epidermal Growth ◽

Transcription 3

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Immunohistochemical Analysis of Phosphotyrosine Signal Transducer and Activator of Transcription 3 and Epidermal Growth Factor Receptor Autocrine Signaling Pathways in Head and Neck Cancers and Metastatic Lymph Nodes

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-07-1543 ◽

2008 ◽

Vol 14 (5) ◽

pp. 1303-1309 ◽

Cited By ~ 32

Author(s):

Raja R. Seethala ◽

William E. Gooding ◽

Phoebe N. Handler ◽

Bobby Collins ◽

Qing Zhang ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Lymph Nodes ◽

Growth Factor Receptor ◽

Immunohistochemical Analysis ◽

Signal Transducer ◽

Autocrine Signaling ◽

Epidermal Growth ◽

Transcription 3

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Enhanced Sensitivity of Pancreatic Cancer Cells to Concurrent Inhibition of Aberrant Signal Transducer and Activator of Transcription 3 and Epidermal Growth Factor Receptor or Src

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.109.162669 ◽

2010 ◽

Vol 333 (2) ◽

pp. 373-381 ◽

Cited By ~ 24

Author(s):

Soumya Jaganathan ◽

Peibin Yue ◽

James Turkson

Keyword(s):

Pancreatic Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Signal Transducer ◽

Enhanced Sensitivity ◽

Pancreatic Cancer Cells ◽

Epidermal Growth ◽

Transcription 3

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Single-molecule imaging reveals the stoichiometry change of epidermal growth factor receptor during transactivation by β2-adrenergic receptor

Science China Chemistry ◽

10.1007/s11426-017-9072-5 ◽

2017 ◽

Vol 60 (10) ◽

pp. 1310-1317 ◽

Cited By ~ 6

Author(s):

Mingliang Zhang ◽

Kangmin He ◽

Jimin Wu ◽

Nan Li ◽

Jinghe Yuan ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Single Molecule ◽

Adrenergic Receptor ◽

Growth Factor Receptor ◽

Single Molecule Imaging ◽

Β2 Adrenergic Receptor ◽

Epidermal Growth

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[beta]1 adrenergic receptor ([beta]1AR)‐epidermal growth factor receptor (EGFR) interaction regulates ERK cellular activity

The FASEB Journal ◽

10.1096/fasebj.22.1_supplement.723.1 ◽

2008 ◽

Vol 22 (S1) ◽

Author(s):

Douglas G. Tilley ◽

Howard A. Rockman

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Adrenergic Receptor ◽

Growth Factor Receptor ◽

Cellular Activity ◽

Epidermal Growth ◽

Receptor Beta

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Human epidermal growth factor receptor 2 expressions and Janus-activated kinase/signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway may be associated with clinicopathological features and prognosis of gastric cancer

Journal of Cancer Research and Therapeutics ◽

10.4103/0973-1482.235348 ◽

2018 ◽

Vol 14 (9) ◽

pp. 311 ◽

Cited By ~ 1

Author(s):

Jingwei Fu ◽

Wenjing Xu ◽

Hao Wu ◽

Weijian Sun

Keyword(s):

Gastric Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Growth Factor Receptor ◽

Clinicopathological Features ◽

Cytokine Signaling ◽

Signal Transducer ◽

Suppressor Of Cytokine Signaling ◽

Epidermal Growth ◽

Transcription 3

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