Differential effects of thyroid hormones on energy metabolism of rat slow- and fast-twitch muscles

2005 ◽  
Vol 203 (3) ◽  
pp. 589-598 ◽  
Author(s):  
L. Bahi ◽  
A. Garnier ◽  
D. Fortin ◽  
B. Serrurier ◽  
V. Veksler ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Thyroid Hormones ◽  
Differential Effects ◽  
Fast Twitch

scholarly journals Endocrine And Metabolic Adaptations Of Calves To Extra-Uterine Life

2015 ◽  
Vol 65 (3) ◽  
pp. 297-318 ◽  
Author(s):  
Kirovski Danijela
Keyword(s):  
Energy Metabolism ◽  
Thyroid Hormones ◽  
Energy Intake ◽  
Environmental Temperature ◽  
Endocrine System ◽  
Energy Sources ◽  
Functional Changes ◽  
Metabolic Adaptations ◽  
Newborn Calves ◽  
And Control

AbstractThe transition from intra- to extra-uterine life is one of the greatest physiological challenges that occur in the life of animals. Immediately after birth, newborn calves have to adapt to new environmental and feeding conditions. Namely, at birth a break of the thermal balance occurs, since calves abruptly pass from a 38.8°C temperaturein uteroto an environmental temperature that is generally lower than 20°C. Additionally, at birth, the energy intake shifts from a continuous parenteral supply of nutrients (mainly glucose) to discontinuous colostrum and milk intake with lactose and fat as the main energy sources. Therefore, the most important issues related to metabolic changes during the transition from intra- to extra-uterine life are related to maintaining the homoeothermic conditions and control of energy metabolism. Those metabolic adaptations are under control of the endocrine system that is relatively mature at birth, but still requires morphological and functional changes after birth. Key hormones whose concentrations are significantly changed around birth and are involved in an adequate adaptation of calves to extra-uterine life are those related to stress at birth (cortisol and cathecholamines), glucoregulatory processes (insulin and glucagon), thermogenesis (thyroid hormones) and growth (IGF axis).

Differential effects of thyroid hormones on growth and thyrotropic hormones in rat fetuses near term.

Endocrinology ◽  
1993 ◽  
Vol 132 (5) ◽  
pp. 2056-2064 ◽  
Author(s):  
G Morreale de Escobar ◽  
R Calvo ◽  
F Escobar del Rey ◽  
M J Obregon
Keyword(s):  
Thyroid Hormones ◽  
Rat Fetuses ◽  
Differential Effects ◽  
Near Term

Differential effects of thyroid status on regional H2O2 production in slow- and fast-twitch muscle of ducklings

2012 ◽  
Vol 183 (1) ◽  
pp. 135-143 ◽  
Author(s):  
Benjamin Rey ◽  
Damien Roussel ◽  
Jean-Louis Rouanet ◽  
Claude Duchamp
Keyword(s):  
H2o2 Production ◽  
Thyroid Status ◽  
Differential Effects ◽  
Fast Twitch Muscle ◽  
Fast Twitch

Differential effects of growth hormone and prednisolone on energy metabolism and leptin levels in humans

Metabolism ◽  
1998 ◽  
Vol 47 (1) ◽  
pp. 83-88 ◽  
Author(s):  
Troels Wolthers ◽  
Thorbjørn Grøfte ◽  
Helen Nørrelund ◽  
Per L. Poulsen ◽  
Frederick Andreasen ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Energy Metabolism ◽  
Differential Effects

scholarly journals Cold exposure distinctively modulates parathyroid and thyroid hormones in cold-acclimatized and non-acclimatized humans

2020 ◽  
Author(s):  
Zuzana Kovaničová ◽  
Tímea Kurdiová ◽  
Miroslav Baláž ◽  
Patrik Štefanička ◽  
Lukáš Varga ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Thyroid Hormones ◽  
Cold Exposure ◽  
Neck Surgery ◽  
Cross Sectional Study ◽  
Whole Body ◽  
Cross Sectional ◽  
Brown Adipose ◽  
Ice Water

AbstractContextCold-induced activation of thermogenesis modulates energy metabolism, but the role of humoral mediators is not completely understood.ObjectiveTo investigate the role of parathyroid and thyroid hormones in acute and adaptive response to cold in humans.DesignCross-sectional study examining acute response to ice-water swimming and to experimental non-shivering thermogenesis (NST) induction in individuals acclimatized and non-acclimatized to cold. Seasonal variation in energy metabolism of ice-water swimmers and associations between circulating PTH and molecular components of thermogenic program in brown adipose tissue (BAT) of neck-surgery patients were evaluated.SettingClinical Research Center.Patients, ParticipantsIce-water swimmers (winter swim n=15, NST-induction n=6), non-acclimatized volunteers (NST-induction, n=11, elective neck surgery n = 36).Main Outcomes and ResultsIn ice-water swimmers, PTH and TSH increased in response to 15min winter swim, while activation of NST failed to regulate PTH and lowered TSH. In non-acclimatized men, NST-induction decreased PTH and TSH. Positive correlation between systemic levels of PTH and whole-body metabolic preference for lipids as well as BAT 18F-FDG uptake was found across the two populations. Moreover, NST-cooling protocol-induced changes in metabolic preference for lipids correlated positively with changes in PTH. Finally, variability in circulating PTH correlated positively with UCP1/UCP1, PPARGC1A and DIO2 in BAT from neck surgery patients.ConclusionsRegulation of PTH and thyroid hormones during cold exposure in humans depends on the cold acclimatization level and/or cold stimulus intensity. Role of PTH in NST is substantiated by its positive relationships with whole-body metabolic preference for lipids, BAT volume and UCP1 content.

scholarly journals Effects of physical activity on prolactin and thyroid hormones

2021 ◽  
Vol 2 (3) ◽  
pp. 25-29
Author(s):  
T. Yu. Demidova ◽  
D. V. Skuridina ◽  
A. S. Kochina
Keyword(s):  
Physical Activity ◽  
Energy Metabolism ◽  
Thyroid Hormones ◽  
Pituitary Gland ◽  
Human Body ◽  
Anterior Pituitary ◽  
High Stress ◽  
Anterior Pituitary Gland ◽  
Physiological Processes ◽  
Adaptive Reactions

Thyroid hormones thyroxine and triiodothyronine, as well as the hormone of anterior pituitary gland prolactin, play an important role in various physiological processes in the human body. In high-stress situations, these hormones act to maintain homeostasis. One of the severe stressors is physical activity. Prolactin and thyroid hormones control the energy metabolism during physical activity, and are also an important link in adaptive reactions in response to physical activity.

Thyroid Hormones and Mitochondria

2002 ◽  
Vol 22 (1) ◽  
pp. 17-32 ◽  
Author(s):  
Fernando Goglia ◽  
Elena Silvestri ◽  
Antonia Lanni
Keyword(s):  
Energy Metabolism ◽  
Thyroid Hormones ◽  
Uncoupling Protein ◽  
Atp Synthesis ◽  
Energy Transduction ◽  
Clear Cut ◽  
Expression Of Genes ◽  
Molecular Determinant ◽  
Mitochondrial Functions ◽  
Oxidative Processes

Because of their central role in the regulation of energy-transduction, mitochondria, the major site of oxidative processes within the cell, are considered a likely subcellular target for the action that thyroid hormones exert on energy metabolism. However, the mechanism underlying the regulation of basal metabolic rate (BMR) by thyroid hormones still remains unclear. It has been suggested that these hormones might uncouple substrate oxidation from ATP synthesis, but there are no clear-cut data to support this idea. Two iodothyronines have been identified as effectors of the actions of thyroid hormones on energy metabolism: 3',3,5-triiodo-L-thyronine (T3) and 3,5-diiodo-L-thyronine (T2). Both have significant effects on BMR, but their mechanisms of action are not identical. T3 acts on the nucleus to influence the expression of genes involved in the regulation of cellular metabolism and mitochondria function; 3,5-T2, on the other hand, acts by directly influencing the mitochondrial energy-transduction apparatus. A molecular determinant of the effects of T3 could be uncoupling protein-3 (UCP-3), while the cytochrome-c oxidase complex is a possible target for 3,5-T2. In conclusion, it is likely that iodothyronines regulate energy metabolism by both short-term and long-term mechanisms, and that they act in more than one way in affecting mitochondrial functions.

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