Group exposure and response prevention for college students with social anxiety: A randomized clinical trial

2019 ◽  
Vol 75 (9) ◽  
pp. 1489-1507 ◽  
Author(s):  
Brian A. Zaboski ◽  
Diana Joyce‐Beaulieu ◽  
John H. Kranzler ◽  
Joseph P. McNamara ◽  
Cindi Gayle ◽  
...  
Keyword(s):  
College Students ◽  
Clinical Trial ◽  
Social Anxiety ◽  
Randomized Clinical Trial ◽  
Response Prevention ◽  
Exposure And Response Prevention

scholarly journals A Randomized Clinical Trial Evaluating a Combined Alcohol Intervention for High-Risk College Students

2009 ◽  
Vol 70 (4) ◽  
pp. 555-567 ◽  
Author(s):  
Rob Turrisi ◽  
Mary E. Larimer ◽  
Kimberly A. Mallett ◽  
Jason R. Kilmer ◽  
Anne E. Ray ◽  
...  
Keyword(s):  
College Students ◽  
Clinical Trial ◽  
High Risk ◽  
Randomized Clinical Trial ◽  
Alcohol Intervention

scholarly journals Mandated college students’ response to sequentially administered alcohol interventions in a randomized clinical trial using stepped care.

2016 ◽  
Vol 84 (2) ◽  
pp. 103-112 ◽  
Author(s):  
Brian Borsari ◽  
Molly Magill ◽  
Nadine R. Mastroleo ◽  
John T. P. Hustad ◽  
Tracy O'Leary Tevyaw ◽  
...  
Keyword(s):  
College Students ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Stepped Care ◽  
Alcohol Interventions

scholarly journals Randomized clinical trial of A brief, scalable intervention for mental health Sequelae in college students during the COVID-19 pandemic

2021 ◽  
pp. 104015
Author(s):  
Shireen L. Rizvi ◽  
Jesse Finkelstein ◽  
Annmarie Wacha-Montes ◽  
April L. Yeager ◽  
Allison K. Ruork ◽  
...  
Keyword(s):  
Mental Health ◽  
College Students ◽  
Clinical Trial ◽  
Randomized Clinical Trial

A Randomized Clinical Trial: The Use of Hypnosis to Improve Academic Self-Concept and Self-Concept in College Students

2011 ◽  
Author(s):  
Steffanie J. Scholze ◽  
Marty Sapp ◽  
Jane Lui ◽  
Daun R. Kihslinger ◽  
Ling-Lun Chien ◽  
...  
Keyword(s):  
College Students ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Self Concept

scholarly journals Expectancy effects on serotonin and dopamine transporters during SSRI treatment of social anxiety disorder: a randomized clinical trial

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Olof R. Hjorth ◽  
Andreas Frick ◽  
Malin Gingnell ◽  
Johanna M. Hoppe ◽  
Vanda Faria ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Anxiety Disorder ◽  
Social Anxiety ◽  
Randomized Clinical Trial ◽  
Social Anxiety Disorder ◽  
Serotonin Transporter ◽  
Psychological Factors ◽  
Anxiety Reduction ◽  
Symptom Improvement ◽  
Ssri Treatment

AbstractIt has been extensively debated whether selective serotonin reuptake inhibitors (SSRIs) are more efficacious than placebo in affective disorders, and it is not fully understood how SSRIs exert their beneficial effects. Along with serotonin transporter blockade, altered dopamine signaling and psychological factors may contribute. In this randomized clinical trial of participants with social anxiety disorder (SAD) we investigated how manipulation of verbally-induced expectancies, vital for placebo response, affect brain monoamine transporters and symptom improvement during SSRI treatment. Twenty-seven participants with SAD (17 men, 10 women), were randomized, to 9 weeks of overt or covert treatment with escitalopram 20 mg. The overt group received correct treatment information whereas the covert group was treated deceptively with escitalopram, described as an active placebo in a cover story. Before and after treatment, patients underwent positron emission tomography (PET) assessments with the [11C]DASB and [11C]PE2I radiotracers, probing brain serotonin (SERT) and dopamine (DAT) transporters. SAD symptoms were measured by the Liebowitz Social Anxiety Scale. Overt was superior to covert SSRI treatment, resulting in almost a fourfold higher rate of responders. PET results showed that SERT occupancy after treatment was unrelated to anxiety reduction and equally high in both groups. In contrast, DAT binding decreased in the right putamen, pallidum, and the left thalamus with overt SSRI treatment, and increased with covert treatment, resulting in significant group differences. DAT binding potential changes in these regions correlated negatively with symptom improvement. Findings support that the anxiolytic effects of SSRIs involve psychological factors contingent on dopaminergic neurotransmission while serotonin transporter blockade alone is insufficient for clinical response.

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