scholarly journals First report of the spectrum of δ‐globin gene mutations among women of reproductive age in Fujian area—Discrimination of δ‐thalassemia, α‐thalassemia, and Iron Deficiency Anemia

2020 ◽  
Vol 34 (11) ◽  
Author(s):  
Meihuan Chen ◽  
Hailong Huang ◽  
Lingji Chen ◽  
Na Lin ◽  
Min Zhang ◽  
...  
2018 ◽  
Vol 08 (11) ◽  
pp. 993-1005 ◽  
Author(s):  
Parag Biniwale ◽  
Bhaskar Pal ◽  
Tripura Sundari ◽  
Gorakh Mandrupkar ◽  
Nikhil Datar ◽  
...  

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 699-699
Author(s):  
Lorraine Yeung ◽  
Mona Duggal ◽  
Reena Das ◽  
Jorge Rosenthal ◽  
Swati Bhardwaj ◽  
...  

Abstract Objectives Anemia is a public health problem in women of reproductive age in many low- and medium-income countries including India. Maternal anemia can cause low birth weight, impaired fetal growth, and preterm birth. We assessed the baseline prevalence of anemia, iron deficiency (ID), iron deficiency anemia (IDA), and inflammation using c-reactive protein (CRP) among non-pregnant, non-lactating women of reproductive age living in the Ambala District, Haryana, India prior to the start of a wheat flour fortification program. Methods We conducted a multistage cluster probability household and biomarker survey and analyzed venous blood samples from non-pregnant, non-lactating women aged 18–49 years residing in rural areas of two subdistricts in the Ambala District. Factors of interest were: anemia, hemoglobin < 12.0 g/dL; ID, serum ferritin < 15μg/L;  IDA,  presence of both anemia and iron deficiency; inflammation, CRP > 5 mg/L. We used the BRINDA regression adjustment for ferritin to account for inflammation. Prevalence and 95% confidence intervals (CI) for anemia, ID, IDA, and CRP were estimated. Results Among 775 non-pregnant, non-lactating women of reproductive age, 54.3% (95% CI; 50.7, 58.0) had anemia, 86.9% (95% CI; 84.3, 89.2) were iron deficient, and 15.1% (95% CI; 12.5, 18.1) had inflammation. Among those with anemia, 58.2% (95 CI; 54.3, 62.0) had iron deficiency anemia. Conclusions Anemia, iron deficiency, and iron deficiency anemia among non-pregnant, non-lactating women of reproductive age in Haryana are significant public health concerns. The findings from the survey helped quantify the burden of inadequate iron intake and informed the Haryana government's prevention strategy aimed at reducing micronutrient deficiencies through a wheat flour fortification program. Funding Sources Centers for Disease Control and Prevention.


2019 ◽  
Vol 16 (32) ◽  
pp. 471-477
Author(s):  
Leila I. ARYSTAN ◽  
Gulmira M. MULDAEVA ◽  
Leila S. HAYDARGALIEVA ◽  
Damira K. PAKHOMOVA ◽  
Yernar B. ISKAKOV

The problem of iron deficiency is urgent in many countries, regardless of the socio-economic standards of living. Among biomedical problems, the study of biochemical blood parameters is of paramount importance. A great interest in various aspects of this issue is not accidental, since the transport function of the blood largely depends on it and, consequently, the efficient delivery of oxygen, glucose, amino acids, fats, vitamins, mineral salts, hormones, mediators, antibodies and metabolites to the micro-zones in the tissues. The purpose of this article is to study the hematological status and the state of the red blood cell membrane in women of reproductive age suffering from iron deficiency anemia (IDA). Iron deficiency anemia (IDA) is a combination of clinical and hematological symptoms characterized by impaired hemoglobin formation due to iron deficiency in serum and bone marrow, as well as the development of trophic disorders in the organs and tissues. During the study, a complete blood count was performed using an enzyme-linked immunosorbent assay, using the kits produced by JSC Vector-Best, and the Kamyshnikov method. Based on the results of the study of the erythrocyte sorption capacity (ESC) in women of reproductive age with IDA, it was established that this parameter is 1.2 times higher than that in the control group. The development of anemia is associated with significant changes in the osmotic stability of the erythrocytes, which results in an increase in the proportion of both unstable and high-resistance erythrocytes. The scientific novelty of the article is that the authors established the key parameters for iron deficiency anemia detection.


Doctor Ru ◽  
2020 ◽  
Vol 19 (8) ◽  
pp. 20-24
Author(s):  
V.E. Radzinsky ◽  
◽  
A.V. Solovyeva ◽  
N.G. Fedotov ◽  
◽  
...  

Objective of the Review: To set forth the frequency and prevalence of the anemia syndrome in non-pregnant and pregnant women and approaches to treating this disorder. Key Points: Anemia syndrome is the most common health problem in contemporary women. The leading cause of iron deficiency in women of reproductive age is abnormal uterine bleeding (AUB). Anemia in women significantly reduces their ability to work and quality of life, and increases the rates and severity of complications in pregnant women and parturients. It is also a significant contributor to maternal mortality and fetal and neonatal morbidity. Treating anemia in pregnant women presents certain challenges. In the period between the first trimester and delivery, there is an 8-fold increase in the requirement for iron; therefore, hemoglobin levels return to normal slowly. The active ingredient of Ferrum Lek is a ferric hydroxide polymaltose complex, which is as effective as medications containing ferrous sulfate, but is significantly better tolerated by patients and easier to use. The active transport of iron allows its controlled absorption from the polymaltose complex, minimizing the risk of an increase in serum levels of iron not bound to transferrin. This ensures that this medication is very safe and eliminates the risk of overdose or poisoning. Conclusion: Anemia syndrome is the most common type of homeostatic imbalance in women of reproductive age. It most often results from frequent and abundant uterine bleeding (AUB). Therefore, an obstetrician-gynecologist plays the leading role in identifying menstrual disorders and choosing therapies to reduce blood loss. A gynecologist will also work with an internist (hematologist) in treating iron deficiency anemia. Keywords: anemia syndrome, iron deficiency anemia, abnormal uterine bleeding, ferric hydroxide polymaltose complex.


2019 ◽  
Vol 15 ◽  
pp. 100425
Author(s):  
Thangavel Mahalingam Vijayakumar ◽  
Ananthathandavan Priyadharshini ◽  
Sivaguru Paramesh Ahalya ◽  
Karunanidhi Santhana Lakshmi ◽  
Logaraj Muthunarayanan ◽  
...  

2018 ◽  
Vol 4 (3) ◽  
pp. 123-131
Author(s):  
CS Nagesh ◽  
◽  
Wajeeha Begum ◽  
Kouser Fathima Firdose ◽  
◽  
...  

Back ground and objective: Anemia is the most widespread nutrient deficiency in the world, most often associated with iron deficiency. The functional consequences of anemia include an increased risk of maternal and perinatal mortality; poor pregnancy outcomes viz. low birth weight and preterm birth. Anemia is a major public health concern globally, especially among women and children. Anemia affects 24.8% of the population, the highest prevalence is among preschool-aged children (47.4%), followed by pregnant women (41.8%) and women of reproductive age. Methods: This randomized, single blind, standard controlled study compared efficacy of qurs kushtae Faulad and jawarishe Amla against cap Fefol on diagnosed subjects of iron deficiency anemia. Test group (n=20) received jawarishe Amla 7g with water and qurs kushtae Faulad (Hamdard) 2 twice a day for 2 months after meals. Whereas control group received cap Fefol 1 bid after meals for 2 months. The primary outcome measure was improvement in Hb% and PCV. Results: Iron deficiency anemia is significantly improved (P <0.001**) after intervention in two groups. There is significant improvement in Hb% with the mean±SD before treatment is 9.68±1.16 and after treatment 11.24±1.51 with p value is <0.001**. The mean±SD of PCV before treatment is 30.36±2.75 and after treatment is 33.92±4.76 with p value of 0.002**, which is more significant clinically and statistically. Interpretation & Conclusion: Test drug provide statistically significant improvement in iron deficiency anemia. It can serve an alternative treatment for Iron deficiency anemia. Further research is certified on large sample size.


2010 ◽  
Vol 1 (1) ◽  
pp. 12-13 ◽  
Author(s):  
Tabish Hussain ◽  
Li Yu Shu

Objective: To assess the level of awareness about causes, prevention and treatment of iron deficiency anemia among women of reproductive age in Hubei province, a south eastern province of China.Method: Cross sectional study was conducted by using a self designed standardized pretested questionnaire in peripheral areas of Wuhan city, the capital of Hubei province from January 2009 to December 2009.Women aged 18-45 years without any previous history of medical or gynecological problems were    recruited.Results: A total 385 women were surveyed for Iron Deficiency Anemia (IDA).77.9% women (n=300) were aware of the term IDA, with the highest proportion of 88.1% falling in age group 25-35 years. Most of the women were aware of the fact that their diet contains iron and its importance in health.  Women who had children and of working class had greater knowledge about the iron deficiency anemia.Conclusion: Awareness regarding IDA is directly linked with the educational and social status of a community and is found to be increasing with the passage of time with exploration and accessibility to media and health care facilities. Women of younger ages are more concern about their own health and much careful about their expected babies in terms of nutritional facts as compared to the elder ladies.Keywords: Iron deficiency anemia; Reproductive ageDOI: 10.3126/ajms.v1i1.2607Asian Journal of Medical Sciences Vol.1(1) 2010 p.12-13 


2020 ◽  
Vol 3 (4) ◽  
pp. 276-281
Author(s):  
М.S. Selikhova ◽  
◽  
P.A. Soltys ◽  
L.S. Kalacheva ◽  
◽  
...  

The prevalence of iron-deficiency anemia (IDA) is steadily increasing. IDA is more common in women of reproductive age, pregnant women, and adolescent girls thus accounting for the importance of this issue in obstetrics and gynecology. Abnormal uterine bleeding (AUB) is one of the most common causes of IDA both in the puberty and reproductive period which requires hemostasis as well as addressing iron deficiency. A high rate of IDA was also reported in women with pelvic inflammatory diseases; this should considered when managing this large group of gynecological patients. The treatment for anemia or latent iron deficiency is performed for a long time, therefore, the selection of a medication is particularly important. Peroral Tardyferon® containing 80 mg of iron meets all modern-day requirements for anti-anemic drugs and is recommended for anemia resulting from AUB both in women of reproductive age and adolescent girls. Case studies illustrate high efficacy and good tolerability of this medication. KEYWORDS: iron-deficiency anemia, pregnancy, abnormal uterine bleeding in puberty, heavy menstrual bleeding, genital inflammation, high efficacy, compliance. FOR CITATION: Selikhova М.S., Soltys P.A., Kalacheva L.S. Prevention and treatment for iron-deficiency anemia in obstetrical gynecological practice. Russian Journal of Woman and Child Health. 2020;3(4):276–281. DOI: 10.32364/2618-8430-2020-3-4-276-281.


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