scholarly journals The association of serum vitamin D–binding protein and 25‐hydroxyvitamin D in pre‐operative and post‐operative colorectal cancer

2019 ◽  
Vol 34 (5) ◽  
Author(s):  
Yuanzi Liang ◽  
Liejun Jiang ◽  
Xiaowei Chi ◽  
Steven Hochwald ◽  
Feng Qiu ◽  
...  
2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Hou-Qun Ying ◽  
Hui-Ling Sun ◽  
Bang-Shun He ◽  
Yu-Qin Pan ◽  
Feng Wang ◽  
...  

PLoS ONE ◽  
2014 ◽  
Vol 9 (7) ◽  
pp. e102966 ◽  
Author(s):  
Gabriella M. Anic ◽  
Stephanie J. Weinstein ◽  
Alison M. Mondul ◽  
Satu Männistö ◽  
Demetrius Albanes

2014 ◽  
Vol 146 (5) ◽  
pp. S-176
Author(s):  
Gauree G. Konijeti ◽  
Mingyang Song ◽  
Chen Yuan ◽  
Ashwin N. Ananthakrishnan ◽  
Shuji Ogino ◽  
...  

2016 ◽  
Vol 9 (8) ◽  
pp. 664-672 ◽  
Author(s):  
Mingyang Song ◽  
Gauree Gupta Konijeti ◽  
Chen Yuan ◽  
Ashwin N. Ananthakrishnan ◽  
Shuji Ogino ◽  
...  

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Bankole Peter Kuti ◽  
Alex Ifeoluwa Akinwumi ◽  
Demilade Kehinde Kuti ◽  
Kazeem Olanrewaju Amoo

Abstract Background The pathologic basis of childhood community-acquired pneumonia (CAP) involves the generation of reactive oxygen species by immune cells leading to cellular damage and lung congestion. Serum antioxidants and vitamin D with immunomodulatory properties therefore hold prospects in the prevention and management of pneumonia in children. This case–control study set out to compare the serum 25-hydroxyvitamin D (25-OHD) and total antioxidant capacity (TAC) in Nigerian children with CAP and age- and sex-matched controls and to relate these parameters with pneumonia severity and outcome—length of hospital stay (LOH). Results A total of 160 children (80 each for CAP and controls) were recruited. The median (IQR) age was 1.8 (0.6–4.0) years, male:female 1.7:1, 63 (78.8%) and 11 (13.8%) of CAP group had severe pneumonia and parapneumonic effusions, respectively. Serum 25-OHD (33.8 (18.3) ng/ml vs. 41.9 (12.3) ng/ml; p = 0.010) and TAC (6.1 (4.4–8.1) ng/dl vs. 7.2 (4.7–17.5) ng/dl; p = 0.023) were lower in children with CAP than controls. Lower serum 25-OHD was observed in severe than non-severe pneumonia (30.5(17.1) ng/ml vs. 46.3 (17.6) ng/ml; p = 0.001) but LOH did not correlate with serum 25-OHD and TAC. Conclusion Children with CAP had lower serum vitamin D and antioxidants than controls, and severe pneumonia was significantly associated with suboptimal serum vitamin D. They however were not related to pneumonia outcome. Optimal serum vitamin D and antioxidants may play a role in reducing the incidence of childhood CAP in Nigerian children.


2018 ◽  
Vol 144 (10) ◽  
pp. 2401-2407 ◽  
Author(s):  
Chen Yuan ◽  
Irene M. Shui ◽  
Kathryn M. Wilson ◽  
Meir J. Stampfer ◽  
Lorelei A. Mucci ◽  
...  

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