scholarly journals Comparison of droplet digital PCR and direct Sanger sequencing for the detection of the BRAF V600E mutation in papillary thyroid carcinoma

2019 ◽  
Vol 33 (6) ◽  
Author(s):  
Zhuo Wang ◽  
Kejing Sun ◽  
Changwen Jing ◽  
Haixia Cao ◽  
Rong Ma ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Sanger Sequencing ◽  
Digital Pcr ◽  
Droplet Digital Pcr ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Papillary Thyroid

Mixed histiocytosis with BRAF (V600E) mutation and papillary thyroid carcinoma

2019 ◽  
Author(s):  
Francoise Archambeaud ◽  
Pauline Vital ◽  
Gilles Russ ◽  
Isabelle Pommepuy ◽  
Julien Haroche ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Papillary Thyroid

Imbalance in DNA repair machinery is associated with BRAF V600E mutation and tumor aggressiveness in papillary thyroid carcinoma

2018 ◽  
Vol 472 ◽  
pp. 140-148 ◽  
Author(s):  
Bruna S. Lutz ◽  
Natalia M. Leguisamo ◽  
Nicole K. Cabral ◽  
Helena C. Gloria ◽  
Keli C. Reiter ◽  
...  
Keyword(s):  
Dna Repair ◽  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Papillary Thyroid ◽  
Tumor Aggressiveness

scholarly journals Clinical utility of immunohistochemistry for the detection of the BRAF v600e mutation in papillary thyroid carcinoma

Surgery ◽  
2013 ◽  
Vol 154 (6) ◽  
pp. 1199-1205 ◽  
Author(s):  
Jonathan Zagzag ◽  
Aron Pollack ◽  
Linda Dultz ◽  
Shumon Dhar ◽  
Jennifer B. Ogilvie ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Clinical Utility ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Papillary Thyroid

Correlation between BRAF V600E mutation and clinicopathological features in pediatric papillary thyroid carcinoma

2017 ◽  
Vol 60 (7) ◽  
pp. 729-738 ◽  
Author(s):  
Jiangqiao Geng ◽  
Huanmin Wang ◽  
Yuanhu Liu ◽  
Jun Tai ◽  
Yaqiong Jin ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Braf V600e Mutation ◽  
Clinicopathological Features ◽  
Braf V600e ◽  
Papillary Thyroid

scholarly journals BRAF V600E Immunoexpression in Papillary Thyroid Carcinoma and Its Association with Prognostic Factors and Histopathologic Variant

Medicinus ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. 12
Author(s):  
Erna Kristiani ◽  
Endang SR Hardjolukito ◽  
Agnes S Harahap ◽  
Benyamin Makes
Keyword(s):  
Prognostic Factors ◽  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Clinicopathological Characteristics ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Papillary Thyroid ◽  
Tall Cell Variant ◽  
Tall Cell ◽  
Cell Variant

<p><strong>Aim: </strong>to provide additional information regarding the clinicopathological characteristics of Papillary Thyroid Carcinoma (PTC). Methods: Fifty patient with PTC were reviewed to determine prognostic factors such as age, gender, size of tumor and histologic variant. BRAF V600E mutation was detected by immunohistochemical staining and assessed with H score. Result: BRAF V600E mutations were detected in 17 (34%) cases. There were seven cases with extrathyroidal extension (ETE) p 0,04, 11 cases with lymph node metastasis (LNM) p &lt; 0,001, and 8 cases with tall cell variant p 0,047.The cases with positive BRAF V600E mutation had mean age of 44.71 years, and the size of the tumor between 0.1-4cm. Six cases of them are male and 11 female.</p><p><strong>Conclusion:</strong> There were significant relationships between BRAF V600E mutation with ETE, LNM, and tall cell variant. There was no significant relationship between BRAF V600E mutation, either with age, gender, or size of the tumor. BRAF V600E immunohistochemical examination can be performed as additional investigation for PTC patients.</p>

Sign in / Sign up

Export Citation Format

Share Document