scholarly journals Analysis of estrogen and progesterone receptor gene polymorphisms in leiomyoma

2018 ◽  
Vol 33 (3) ◽  
pp. e22704
Author(s):  
Muhammed Toprak ◽  
Omer Ates ◽  
Asker Zeki Ozsoy ◽  
Nihan Bozkurt ◽  
Saime Sezer Sondas ◽  
...  
Keyword(s):  
Progesterone Receptor ◽  
Gene Polymorphisms ◽  
Receptor Gene ◽  
Progesterone Receptor Gene ◽  
Receptor Gene Polymorphisms ◽  
Estrogen And Progesterone Receptor

scholarly journals Involvement of estrogen and progesterone receptor gene polymorphisms in the development of uterine fibroids

2020 ◽  
Vol 3_2020 ◽  
pp. 127-132
Author(s):  
Altukhova O.B. Altukhova ◽  
Radzinsky V.E. Radzinsky ◽  
Polyakova I.S. Polyakova ◽  
Churnosov M.I. Churnosov ◽  
◽  
...  
Keyword(s):  
Progesterone Receptor ◽  
Gene Polymorphisms ◽  
Receptor Gene ◽  
Uterine Fibroids ◽  
Progesterone Receptor Gene ◽  
Receptor Gene Polymorphisms ◽  
Estrogen And Progesterone Receptor

scholarly journals Frequencies of interleukin-6, GST and progesterone receptor gene polymorphisms in postmenopausal women with low bone mineral density

2014 ◽  
Vol 132 (1) ◽  
pp. 36-40 ◽  
Author(s):  
Katia Franco Moura ◽  
Mauro Haidar ◽  
Claudio Bonduki ◽  
Paulo Cezar Feldner Junior ◽  
Ismael Silva ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Progesterone Receptor ◽  
Postmenopausal Women ◽  
Interleukin 6 ◽  
Gene Polymorphisms ◽  
Receptor Gene ◽  
Mineral Density ◽  
T Score ◽  
Progesterone Receptor Gene ◽  
Receptor Gene Polymorphisms

CONTEXT AND OBJECTIVE: Osteoporosis is a skeletal disorder characterized by low bone mineral density (BMD). Studies have shown that some of the genetic components relating to lower BMD may be detected by polymorphisms. Our aim was to evaluate the frequencies of interleukin-6, GST and progesterone receptor gene polymorphisms in postmenopausal women with low BMD. DESIGN AND SETTING: Cross-sectional study, conducted in a public university in São Paulo, Brazil. METHODS : We evaluated interleukin-6 (IL-6), progesterone receptor gene (PROGINS) and glutathione S-transferase (GST) polymorphisms in 110 postmenopausal women with no previous use of hormone therapy. Tests were performed using DNA-PCR, from oral scrapings. We used Student's t-test and a logistic regression model for statistical analysis. RESULTS : Regarding IL-6 polymorphism, 58.2% of the patients were homozygotes (GG) and 41.8% had allele C (heterozygote or mutant homozygote + GC or CC). PROGINS genotype polymorphism was absent in 79% (wild homozygote or P1/P1) and present in 20.9% (heterozygote or P1/P2). Regarding GSTM1 polymorphism, the allele (1/1) was present in 72.7% of the patients and was absent in 27.3%. We found that IL-6 polymorphism had statistically significant correlations with the L2-L4 T-score (P = 0.032) and with BMD (P = 0.005). Women with IL-6 polymorphism were 2.3 times more likely to have a L2-L4 T-score of less than -1, compared with those not presenting this polymorphism. CONCLUSION: IL-6 gene polymorphism was correlated with low BMD, whereas the PROGINS and GSTM1 polymorphisms did not show any correlation.

Progesterone receptor gene polymorphisms are not associated with preterm birth in a Hispanic population

2008 ◽  
Vol 103 (2) ◽  
pp. 153-157 ◽  
Author(s):  
Laura Diaz-Cueto ◽  
Pablo Dominguez-Lopez ◽  
Julio Cantillo-Cabarcas ◽  
Gloria Perez-Figueroa ◽  
Miguel Arechavaleta-Velasco ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Progesterone Receptor ◽  
Gene Polymorphisms ◽  
Receptor Gene ◽  
Hispanic Population ◽  
Progesterone Receptor Gene ◽  
Receptor Gene Polymorphisms

Progesterone Receptor Gene Polymorphisms of rs1042838 and New Mutation in Ovarian Endometriosis in Indonesian Women

2017 ◽  
Vol 23 (7) ◽  
pp. 6906-6908
Author(s):  
Asmarinah ◽  
Ririn Rahmala Febri ◽  
Aisyah Rifani ◽  
Adita Hadining Putri ◽  
Raden Muharam
Keyword(s):  
Progesterone Receptor ◽  
Gene Polymorphisms ◽  
Receptor Gene ◽  
New Mutation ◽  
Ovarian Endometriosis ◽  
Progesterone Receptor Gene ◽  
Receptor Gene Polymorphisms
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