scholarly journals Shortened mean erythrocyte age in female patients with type 2 diabetes mellitus

2018 ◽  
Vol 33 (2) ◽  
pp. e22681
Author(s):  
Masafumi Koga ◽  
Shinya Inada ◽  
Hiroko Ijima ◽  
Hideaki Jinnouchi ◽  
Yasuhiro Ono ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Female Patients ◽  
Erythrocyte Age

scholarly journals Hypomethylation of IL1RN and NFKB1 genes is linked to the dysbalance in IL1β/IL-1Ra axis in female patients with type 2 diabetes mellitus

PLoS ONE ◽  
2020 ◽  
Vol 15 (5) ◽  
pp. e0233737
Author(s):  
Sona Margaryan ◽  
Eva Kriegova ◽  
Regina Fillerova ◽  
Veronika Smotkova Kraiczova ◽  
Gayane Manukyan
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Female Patients

scholarly journals Study of Drug Prescription Pattern of Obese and Non-Obese Patients with Type-II Diabetes with or without Hypertension

2020 ◽  
Vol 6 (1) ◽  
pp. 81-93
Author(s):  
Mijala Bajracharya ◽  
S Nakarmi
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Obese Patients ◽  
Age Group ◽  
Waist To Hip Ratio ◽  
Female Patients ◽  
Male Patients ◽  
Oral Hypoglycemic Drugs

Correction: The page numbers were changed from 98-100 to 81-93 on 31/08/2020. Background: Obesity is regarded as worldwide health problems which may put a person at a higher risk of serious health conditions leading to morbidity and mortality. Obesity is a risk factor for many diseases of which hypertension and type-2 diabetes mellitus are the most important. Hypertension, diabetes mellitus and obesity together form 24% of the global risk for mortality. Cardiovascular diseases related to these life-style disorders has major effect on life expectancy and impaired quality of life. Objectives: The study was done to evaluate the drug prescribing pattern of type - 2 diabetes and hypertension in both obese and non-obese patients. Along with it, this study also attempt to find the contributing factors associated with it and different types of drugs selected in those conditions respectively. Method: A descriptive cross-sectional study was conducted in 2074 at Manmohan memorial teaching hospital. A total of 101 out-patient were interviewed, measurements were done to calculate BMI and waist to hip ratio and their prescriptions were reviewed. For Treatment Guideline of HTN, JNC 8[20] was followed and Updated Treatment Guidelines for Type 2 Diabetes by the American Diabetes Association (ADA) [21] was followed in case of diabetes. Result: Among 101 patients studied, 58 were males and 43 were females. Regarding physical activity, only 26.7% of total patients were involved in morning walk and 3% in yoga, remaining 71% of study patients did not involve in any kind of physical exercise. Regarding food habits, 22.8% were smokers, 49.5% were alcoholics and 96% were non-vegetarians. Waist to hip ratio was also observed higher in both males (35.6%) and females (39.6%). Among the101 total participants, the age group of 41-55 years were found to be more obese than other age group (34 in numbers) followed by age group 56-70 which were 16 in numbers. Male patients were more obese (41) than female patients (31). Highest number (31) of the obese patients were diagnosed with type 2 diabetes mellitus, followed by second highest number (26) of patients diagnosed with hypertension and 15 patients with both the conditions. The commonly prescribed oral hypoglycemic drugs were metformin (35.60%) followed by glimepiride (24.80%). Among anti-hypertensive drugs, amlodipine (22.80%) was most common in prescriptions followed by losartan (18.80%) and Telmisartan (17.80%). Conclusion: The results of the present study show that higher number of male patients (41) were obese than female patients (31). About 30% of patients were found obese-diabetic, 26% were obese-hypertensive and 15% were with both obese diabetic and hypertensive condition. Among oral hypoglycemic drugs, metformin (35.60%) was mostly prescribed followed by glimepiride (24.80%). Among antihypertensives, amlodipine (22.8%) was mostly prescribed followed by losartan (18.80%). Atorvastatin (11.9%) was mostly prescribed oral hypolipidemic agent.

Effects of pravastatin on serum adiponectin levels in female patients with type 2 diabetes mellitus

2013 ◽  
Vol 227 (2) ◽  
pp. 355-359 ◽  
Author(s):  
Ji-Hyun Kim ◽  
Ma-Rie Lee ◽  
Jung-Ah Shin ◽  
Sung-Soo Lee ◽  
Jung-Min Lee ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Serum Adiponectin ◽  
Female Patients

scholarly journals GENDER-RELATED ALTERATIONS IN FREE FATTY ACIDS AND OXIDATIVE STRESS IN HYPERTENSION CO-MORBIDLY OCCURRING WITH TYPE 2 DIABETES MELLITUS

2019 ◽  
Vol 16 (2) ◽  
pp. 26-38
Author(s):  
A. J. AKAMO ◽  
R. N. UGBAJA ◽  
O. ADEMUYIWA ◽  
D. I. AKINLOYE ◽  
O. T. SOMADE ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Fatty Acids ◽  
Type 2 Diabetes Mellitus ◽  
Free Fatty Acids ◽  
Female Patients ◽  
And Oxidative Stress ◽  
Plasma Ffas

Increase in plasma free fatty acids (FFAs) concentrations may cause cellular damage via the induction of oxidative stress. The aim of this present study was to investigate FFAs and oxidative stress in hypertension co-morbidly occurring with Type 2 Diabetes Mellitus (T2DM). Age and sex matched control subjects (n=150) and patients (n=470) [hypertensive nondiabetics (HND, n=179), normotensive diabetics (ND, n=132), hypertensive diabetics (HD, n=159)] presenting at the Medical Out-Patient Clinic of the State Hospital, Abeokuta, Nigeria were recruited. Fasting plasma glucose, creatinine, urea, FFAs, thiobarbituric acid reactive substances (TBARS) were determined spectrophotometrically. The presence of either or both diseases resulted in significant increase (p<0.05) in the plasma FFAs and oxidative stress marker-TBARS in different compartments (plasma, erythrocytes andlipoproteins) for both male and female patients when compared with their control counterparts. The increase in FFAs was more marked in comorbidity female when compared with other female patients. There was significant (p<0.05) difference in gender FFAs concentrations. In both controls and patients, FFAs in plasma are significantly (p<0.05) higher in male when compared with their female counterparts. This research revealed biochemical variations in hypertension co-morbidly occurring with T2DMcharacterised by gender-related elevation in FFAs and enhanced oxidative stress. Plasma FFAs might be a good biomarker predicting the occurrence and development of hypertension and/or T2DM.  

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