scholarly journals Are visceral adiposity index and lipid accumulation product reliable indices for metabolic disturbances in patients with type 2 diabetes mellitus?

2017 ◽  
Vol 32 (3) ◽  
pp. e22283 ◽  
Author(s):  
Nebojsa Kavaric ◽  
Aleksandra Klisic ◽  
Ana Ninic
2021 ◽  
Vol 8 (6) ◽  
pp. A152-157
Author(s):  
Asha Augusthy ◽  
Suchanda Sahu ◽  
Ashok Kumar Jeppu

Background: Diabetes mellitus is a metabolic disease known by chronic hyperglycemia which results from defective insulin action and secretion. Metabolic Syndrome consists of a constellation of metabolic abnormalities that confer increased risk of diabetes mellitus. The aim of our study is to find out whether non-invasive, clinically measurable surrogates could be useful in identifying body fat distribution and help predict metabolic syndrome and diabetes risk and to compare the performance of anthropometric indices with lipid indices in identifying metabolic syndrome and diabetes. Methods: 50 individuals with metabolic syndrome ,50 individuals with type 2 diabetes mellitus and 50 controls were selected by purposive sampling technique. For cases and controls history was taken, physical examination was done .Fasting blood sugar, Serum High density lipoprotein and Serum Triglyceride levels were estimated. Body mass index, a body shape index, visceral adiposity index, lipid accumulation factor was calculated. Results: The mean values visceral adiposity index, lipid accumulation factor were significantly increased (p<0.001) in cases compared to controls. Conclusion: Our study concluded that lipid indices visceral adiposity index, lipid accumulation factor is better than anthropometric indices like body mass index, a body shape index in predicting metabolic syndrome and type 2 diabetes mellitus. Anthropometric indices when used should be correlated with metabolic variables and clinical symptoms.


2021 ◽  
pp. 109980042110505
Author(s):  
Arash Mohammadi ◽  
Nahid Bijeh ◽  
Mahtab Moazzami ◽  
Kazem khodaei ◽  
Najmeh Rahimi

Objective To compare the effects of resistance and aerobic training (RT and AT) on spexin (SPX), appetite, lipid accumulation product (LAP), visceral adiposity index (VAI), and body composition in type 2 diabetes mellitus (T2DM) patients. Materials and Methods: Thirty-six T2DM men were randomized to receive RT ( n = 12), AT ( n = 12), or to act as a non-exercise control (CON, n = 12) 3 days a week for 12 weeks. Results: SPX was increased after both RT and AT (66.2% and 46.5%, respectively). VAI, LAP, and homeostasis model assessment-insulin resistance (HOMA-IR) were reduced in both groups, while quantitative insulin sensitivity check index (Quicki) and McAuley’s indexes were increased following both interventions. However, the increases of both hunger and PFC in the RT group were greater than those of the AT. Moreover, the improvement of upper-body strength (41% vs. 10.3%) and lower-body strength (42.2% vs. 20.5%) in the RT group was greater than those of the AT. Conclusion: Our investigation shows that regardless of the modes of the regimen, a 12-week exercise intervention with RT and AT can effectively induce a significant improvement in SPX levels, appetite, LAP, VAI, and body composition in adults with T2DM.


Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 464-P
Author(s):  
BERNHARD ZIERFUSS ◽  
CLEMENS HOEBAUS ◽  
CARSTEN T. HERZ ◽  
RENATE KOPPENSTEINER ◽  
GERIT-HOLGER SCHERNTHANER

Herz ◽  
2014 ◽  
Vol 40 (S3) ◽  
pp. 277-281 ◽  
Author(s):  
Y. Wang ◽  
S. He ◽  
J. He ◽  
S. Wang ◽  
K. Liu ◽  
...  

2021 ◽  
Vol 46 ◽  
pp. S584
Author(s):  
R.H.V. Machado ◽  
A.C. Bersch-Ferreira ◽  
L.R. Silva ◽  
E.R.R. Sady ◽  
D.H.K. Miyada ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Minrui Xu ◽  
Mingtao Huang ◽  
Deren Qiang ◽  
Jianxin Gu ◽  
Yong Li ◽  
...  

Purpose. To determine whether hypertriglyceridemic waist (HTGW) and high lipid accumulation product (LAP) preceded the incidence of type 2 diabetes mellitus (T2DM), and to investigate the interactions of HTGW and LAP with other components of metabolic syndrome on the risk of T2DM. Methods. A total of 15,717 eligible participants without baseline T2DM and aged 35 and over were included from a Chinese rural cohort. Cox proportional hazards regression models were used to estimate the association of HTGW and LAP with the incidence of T2DM, and the restricted cubic spline model was used to evaluate the dose-response association. Results. Overall, 867 new T2DM cases were diagnosed after 7.77 years of follow-up. Participants with HTGW had a higher hazard ratio for T2DM (hazard ratio (HR): 6.249, 95% confidence interval (CI): 5.199-7.511) after adjustment for potential confounders. The risk of incident T2DM was increased with quartiles 3 and 4 versus quartile 1 of LAP, and the adjusted HRs (95% CIs) were 2.903 (2.226-3.784) and 6.298 (4.911-8.077), respectively. There were additive interactions of HTGW (synergy index (SI): 1.678, 95% CI: 1.358-2.072) and high LAP (SI: 1.701, 95% CI: 1.406-2.059) with increased fasting plasma glucose (FPG) on the risk of T2DM. Additionally, a nonlinear ( P nonlinear < 0.001) dose-response association was found between LAP and T2DM. Conclusion. The subjects with HTGW and high LAP were at high risk of developing T2DM, and the association between LAP and the risk of T2DM may be nonlinear. Our study further demonstrates additive interactions of HTGW and high LAP with increased FPG on the risk of T2DM.


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