scholarly journals Evaluation of a novel point-of-care test kit, ABSOGEN™ PCT, in semi-quantitative measurement of procalcitonin in whole blood

2016 ◽  
Vol 31 (6) ◽  
pp. e22111 ◽  
Author(s):  
Hi Jeong Kwon ◽  
Jehoon Lee ◽  
Hae-il Park ◽  
Kyungja Han
Keyword(s):  
Whole Blood ◽  
Quantitative Measurement ◽  
Point Of Care ◽  
Point Of Care Test ◽  
Test Kit

scholarly journals Comparison between B·R·A·H·M·S PCT direct, a new sensitive point-of-care testing device for rapid quantification of procalcitonin in emergency department patients and established reference methods – a prospective multinational trial

2016 ◽  
Vol 54 (4) ◽  
Author(s):  
Alexander Kutz ◽  
Pierre Hausfater ◽  
Michael Oppert ◽  
Murat Alan ◽  
Eva Grolimund ◽  
...  
Keyword(s):  
Emergency Department ◽  
Diagnostic Accuracy ◽  
Whole Blood ◽  
Point Of Care ◽  
Venous Blood ◽  
Reference Method ◽  
Point Of Care Test ◽  
Emergency Department Patients ◽  
Work Up

AbstractProcalcitonin (PCT) is increasingly being used for the diagnostic and prognostic work up of patients with suspected infections in the emergency department (ED). Recently, B·R·A·H·M·S PCT direct, the first high sensitive point-of-care test (POCT), has been developed for fast PCT measurement on capillary or venous blood samples.This is a prospective, international comparison study conducted in three European EDs. Consecutive patients with suspicion of bacterial infection were included. Duplicate determination of PCT was performed in capillary (fingertip) and venous whole blood (EDTA), and compared to the reference method. The diagnostic accuracy was evaluated by correlation and concordance analyses.Three hundred and three patients were included over a 6-month period (60.4% male, median age 65.2 years). The correlation between capillary or venous whole blood and the reference method was excellent: rThis study found a high diagnostic accuracy and a faster time to result of B·R·A·H·M·S PCT direct in the ED setting, allowing shortening time to therapy and a more wide-spread use of PCT.

Multicentre evaluation of a new point-of-care test for the determination of CK-MB in whole blood

2008 ◽  
Vol 46 (5) ◽  
Author(s):  
Evangelos Giannitsis ◽  
Hannsjörg Baum ◽  
Thomas Bertsch ◽  
Martin Juchum ◽  
Margit Müller-Bardorff ◽  
...  
Keyword(s):  
Whole Blood ◽  
Point Of Care ◽  
Point Of Care Test

scholarly journals Rapid, inexpensive, fingerstick, whole-blood, sensitive, specific, point-of-care test for anti-Toxoplasma antibodies

2018 ◽  
Vol 12 (8) ◽  
pp. e0006536 ◽  
Author(s):  
Joseph Lykins ◽  
Xuan Li ◽  
Pauline Levigne ◽  
Ying Zhou ◽  
Kamal El Bissati ◽  
...  
Keyword(s):  
Whole Blood ◽  
Point Of Care ◽  
Specific Point ◽  
Point Of Care Test

scholarly journals Evaluation of a Rapid Whole Blood ELISA for Quantification of Troponin I in Patients with Acute Chest Pain

1999 ◽  
Vol 45 (10) ◽  
pp. 1789-1796 ◽  
Author(s):  
Christopher Heeschen ◽  
Britta U Goldmann ◽  
Lukas Langenbrink ◽  
Guido Matschuck ◽  
Christian W Hamm
Keyword(s):  
Chest Pain ◽  
Whole Blood ◽  
Troponin I ◽  
Point Of Care ◽  
Acute Chest Pain ◽  
Test System ◽  
Healthy Population ◽  
Roc Curve Analysis ◽  
Prognostic Information ◽  
Point Of Care Test

Abstract Background: Troponin I (cTnI) provides important prognostic information in patients with chest pain. We wished to evaluate a rapid, whole-blood analyzer for quantitative point-of-care testing. Methods: A quantitative point-of-care test system (Stratus CS®; Dade-Behring) for cTnI with an incorporated centrifuge was evaluated in 412 patients with chest pain less than 12 h. Results: Results were available within 15 min. CVs were 4.5% at 0.1 μg/L, 4.2% at 0.25 μg/L, and 6.5% at 0.82 μg/L. The detection limit was 0.01 μg/L. The 97.5% percentile in a healthy population was 0.08 μg/L. Based on ROC curve analysis, a threshold of 0.15 μg/L was calculated for the detection of acute myocardial infarction (AMI). With it, sensitivity for the detection of patients with AMI (n = 62) was 63% at arrival and 98% after 4 h (Stratus II®, 48% and 85%, respectively; P <0.01). In 42% of patients with unstable angina (n = 121), cTnI was ≥0.08 μg/L (Stratus II, 28%; P <0.01). During 30 days, death or AMI occurred in 25.5% of these cTnI-positive vs 2.9% of cTnI-negative patients (Stratus II, 29.4% vs 5.8%). Conclusion: The Stratus CS provided better analytical performance and comparable or better prognostic information than the Stratus II.

scholarly journals Development of Immunochromatographic Test Kit for Rapid Detection of Specific IgG4 Antibody in Whole-Blood Samples for Diagnosis of Human Gnathostomiasis

Diagnostics ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 862
Author(s):  
Penchom Janwan ◽  
Pewpan M. Intapan ◽  
Lakkhana Sadaow ◽  
Rutchanee Rodpai ◽  
Hiroshi Yamasaki ◽  
...  
Keyword(s):  
Whole Blood ◽  
Point Of Care ◽  
Venous Blood ◽  
Immunochromatographic Test ◽  
Predictive Values ◽  
Blood Samples ◽  
Test Kit ◽  
Specific Igg4 ◽  
Whole Blood Samples ◽  
Igg4 Antibody

Human gnathostomiasis is a harmful food-borne zoonosis caused by roundworms of the genus Gnathostoma. The parasite can occasionally migrate to the central nervous system, causing life-threatening disease and death. Here, we report a new point-of-care (POC) test kit, the gnathostomiasis blood immunochromatographic test (GB-ICT) kit. The kit is based on recombinant Gnathostoma spinigerum antigen and detects specific IgG4 antibody in whole-blood samples (WBSs). The GB-ICT kit showed potentially high diagnostic values with simulated WBSs (n = 248), which were obtained by spiking patients’ sera with red blood cells. The accuracy, sensitivity, specificity, and positive and negative predictive values were 95.2%, 100%, 93.8%, 81.5%, and 100%, respectively. Ten WBSs from clinically suspected gnathostomiasis patients were all positive according to the GB-ICT kit, while 10 WBSs from healthy volunteers were negative. The GB-ICT kit is a simple and convenient POC testing tool using finger-prick blood samples: venous blood sampling and serum separation processes are not required. The GB-ICT kit can support clinical diagnosis in remote areas and field settings without sophisticated equipment facilities.

Whole Blood Multiple Electrode Aggregometry Is a Reliable Point-of-Care Test of Aspirin-Induced Platelet Dysfunction

2009 ◽  
Vol 109 (1) ◽  
pp. 25-31 ◽  
Author(s):  
Csilla Jámbor ◽  
Christian F. Weber ◽  
Konstanze Gerhardt ◽  
Wulf Dietrich ◽  
Michael Spannagl ◽  
...  
Keyword(s):  
Whole Blood ◽  
Point Of Care ◽  
Platelet Dysfunction ◽  
Multiple Electrode Aggregometry ◽  
Point Of Care Test ◽  
Multiple Electrode
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