scholarly journals The Glycated Albumin (GA) to HbA1c Ratio Reflects Shorter-Term Glycemic Control than GA: Analysis of Patients with Fulminant Type 1 Diabetes

2016 ◽  
Vol 31 (1) ◽  
pp. e22023 ◽  
Author(s):  
Masafumi Koga ◽  
Shinya Inada ◽  
Taisei Nakao ◽  
Ryuzo Kawamori ◽  
Soji Kasayama
Keyword(s):  
Type 1 Diabetes ◽  
Glycemic Control ◽  
Glycated Albumin ◽  
Fulminant Type 1 Diabetes ◽  
Fulminant Type

scholarly journals The glycated albumin to HbA1c ratio is elevated in patients with fulminant type 1 diabetes mellitus with onset during pregnancy

2013 ◽  
Vol 60 (1.2) ◽  
pp. 41-45 ◽  
Author(s):  
Masafumi Koga ◽  
Ikki Shimizu ◽  
Jun Murai ◽  
Hiroshi Saito ◽  
Soji Kasayama ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Glycated Albumin ◽  
Fulminant Type 1 Diabetes ◽  
Fulminant Type

Glycated Albumin to Glycated Hemoglobin Ratio is a Sensitive Indicator of Blood Glucose Variability in Patients with Fulminant Type 1 Diabetes

2012 ◽  
Vol 51 (11) ◽  
pp. 1315-1321 ◽  
Author(s):  
Hiroaki Matsumoto ◽  
Yuko Murase-Mishiba ◽  
Naomune Yamamoto ◽  
Saya Sugitatsu-Nakatsukasa ◽  
Saeko Shibasaki ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Blood Glucose ◽  
Glycated Hemoglobin ◽  
Glycated Albumin ◽  
Glucose Variability ◽  
Sensitive Indicator ◽  
Fulminant Type 1 Diabetes ◽  
Blood Glucose Variability ◽  
Fulminant Type

scholarly journals Serum 1,5-Anhydroglucitol to Glycated Albumin Ratio Can Help Early Distinguish Fulminant Type 1 Diabetes Mellitus from Newly Onset Type 1A Diabetes Mellitus

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Lingwen Ying ◽  
Xiaojing Ma ◽  
Yun Shen ◽  
Jingyi Lu ◽  
Wei Lu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Differential Diagnosis ◽  
Type 1 Diabetes Mellitus ◽  
Autoimmune Diabetes ◽  
Glycated Albumin ◽  
Fulminant Type 1 Diabetes ◽  
Type 1A Diabetes ◽  
Fulminant Type

Background. Fulminant type 1 diabetes mellitus (FT1DM) onsets abruptly and usually occurs within 1 week after the onset of hyperglycemic symptoms. Glycated albumin (GA) and 1,5-anhydroglucitol (1,5-AG) are indicators that reflect short-term glucose levels. This study was aimed at investigating whether the 1,5-AG/GA index (AGI) is a suitable indicator for early FT1DM identification. Methods. A total of 226 subjects were enrolled, all with glycated hemoglobin A1c HbA1c<8.7%. FT1DM was diagnosed based on the 2012 Japan Diabetes Society criteria. Results. The AGI level was 0.54 (0.17–1.36) in the whole group. It was lower in FT1DM patients (0.16 [0.10–0.25]). Among the participants whose HbA1c did not exceed 7.0%, the AGI of FT1DM decreased significantly compared to type 1A diabetes (T1ADM) and latent autoimmune diabetes in adults (LADA) patients (0.16 [0.12–0.26] vs. 0.46 [0.24–0.72] vs. 0.31 [0.19–0.43], both P<0.05). The receiver operating characteristic (ROC) curve showed that AGI can be used to distinguish FT1DM and T1ADM patients with HbA1c<8.7%. Diagnosing FT1DM based on AGI≤0.3 only can help narrow down suspected FT1DM by up to 26.87%. If we diagnosed FT1DM when AGI was ≤0.3 and HbA1c was ≤7.0%, the success rate further increased to 86.57%, among which 85.00% of FT1DM and 87.23% of T1ADM patients were successfully identified. Therefore, using the combination criteria of AGI and HbA1c would improve the differential diagnosis efficacy by 61.11% compared with the AGI criterion only. Conclusion. AGI can help facilitate the early differential diagnosis of FT1DM and T1ADM when HbA1c<8.7%, with an optimal cut-off point of 0.3.

scholarly journals Estimation of Duration of Symptoms in Fulminant Type 1 Diabetes Mellitus Using HbA1c or Glycated Albumin

2012 ◽  
Vol 3 ◽  
pp. JCM.S9509
Author(s):  
Akitsu Kawabe ◽  
Takashi Seta ◽  
Sumie Fujii ◽  
Masayo Yamada ◽  
Shogo Oki ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Glycated Albumin ◽  
Fulminant Type 1 Diabetes ◽  
Duration Of Symptoms ◽  
Actual Duration ◽  
Fulminant Type

Fulminant type 1 diabetes mellitus (FT1DM) develops as a result of very rapid and almost complete destruction of pancreatic β cells. Because of an abrupt increase in plasma glucose, HbA1c and glycated albumin (GA) might increase along with duration of symptoms in FT1DM patients. We attempted to devise a formula to estimate duration of symptoms based on the increased levels in HbA1c or GA. Four patients who developed FT1DM during the course of type 2 diabetes mellitus and in whom HbA1c was measured before onset were investigated in this study. The percents of the estimated duration of symptoms calculated from HbA1c (four patients) and GA (two patients) to the actual duration were 137 ± 88% and 122%, respectively. In FT1DM patients in whom HbA1c and/or GA before onset and at the time of ketoacidosis are measured, duration of symptoms might be estimated with using the increased levels in HbA1c or GA.

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