scholarly journals Evaluation of the HerpeSelect Express Rapid Test in the Detection of Herpes Simplex Virus Type 2 Antibodies in Patients With Genital Ulcer Disease

2014 ◽  
Vol 29 (1) ◽  
pp. 43-46 ◽  
Author(s):  
Hani Al-Shobaili ◽  
Khaled M. Hassanein ◽  
Marwa Salah Mostafa ◽  
Ali Saleh Al Duways
AIDS ◽  
2012 ◽  
Vol 26 (9) ◽  
pp. 1141-1149 ◽  
Author(s):  
Supriya D. Mehta ◽  
Stephen Moses ◽  
Corette B. Parker ◽  
Kawango Agot ◽  
Ian Maclean ◽  
...  

AIDS ◽  
2007 ◽  
Vol 21 (12) ◽  
pp. 1569-1578 ◽  
Author(s):  
J??r??me LeGoff ◽  
Helen A Weiss ◽  
G??rard Gresenguet ◽  
Khonde Nzambi ◽  
Eric Frost ◽  
...  

PLoS Medicine ◽  
2009 ◽  
Vol 6 (11) ◽  
pp. e1000187 ◽  
Author(s):  
Ronald H. Gray ◽  
David Serwadda ◽  
Aaron A. R. Tobian ◽  
Michael Z. Chen ◽  
Frederick Makumbi ◽  
...  

2010 ◽  
Vol 4 (09) ◽  
pp. 572-575 ◽  
Author(s):  
Yusuf A. Agabi ◽  
Edmund B. Banwat ◽  
John D Mawak ◽  
Patricia M Lar ◽  
Nanma Dashe ◽  
...  

Background: Infection with Herpes Simplex Virus Type-2 (HSV-2) is the primary cause of genital herpes and the most common cause of genital ulcer disease (GUD) worldwide.  There is little information on the prevalence of HSV-2 in Nigeria.        Methodology: Specimens were collected from 162 volunteers attending Jos University Teaching Hospital and tested for HSV-2 antibodies using HSV-2 Type specific IgG EIA test kit (Globalemed LLC Alexandria VA, USA). Data were analyzed using SPSS version 13.0. P values ≤ 0.05 were considered significant. numbr Results: Out of the 162 individuals tested, 141 (87.0%) were HSV-2 positive. Infected individuals were more likely to be male than female (92.8% versus 86.4%; P > 0.05). There were high rates of infection in all age groups, and the prevalence increased with age. However, multivariate logistic regression analysis showed that HSV-2 prevalence was not significantly associated with increasing age, sex, marital status, occupation, educational status, and number of sex partners (P > 0.05).   Conclusions: The results highlight the potential public health impact of HSV-2 in Nigeria where anti-HSV-2 testing is not generally performed in all populations, especially considering the risk of neonatal transmission and the attendant complications at birth.


Sexual Health ◽  
2010 ◽  
Vol 7 (1) ◽  
pp. 87 ◽  
Author(s):  
Marshall W. Munjoma ◽  
Munyaradzi P. Mapingure ◽  
Babill Stray-Pedersen

Herpes simplex virus type 2 (HSV-2) causes a chronic infection that is recognised as the leading cause of genital ulcer disease worldwide and is known to increase the risk of HIV infection. In a cross-sectional study we examined risk factors for HSV-2 among 176 pregnant teenagers recruited from three primary health care clinics in Zimbabwe. The prevalence of HSV-2 and HIV were 41.6% and 29.2% respectively. HIV-infected teenagers were more likely to be HSV-2 seropositive compared with the HIV uninfected teenagers, odds ratio (OR) 7.9 (95% confidence interval (CI) 3.7–16.9). In multivariate analysis having an older partner remained independently associated with HSV-2 seropositivity, OR 2.9 (95% CI 1.2–6.9) suggesting that risk factors for HSV-2 seropositivity among pregnant teenagers depend primarily on the behaviour of the male partners.


2008 ◽  
Vol 15 (5) ◽  
pp. 888-890 ◽  
Author(s):  
Jordyn L. Gamiel ◽  
Aaron A. R. Tobian ◽  
Oliver B. Laeyendecker ◽  
Steven J. Reynolds ◽  
Rhoda Ashley Morrow ◽  
...  

ABSTRACT Ugandan subjects (820) were tested by Focus HerpeSelect enzyme-linked immunosorbent assay (ELISA), Kalon herpes simplex virus type 2 ELISA, and BioKit rapid test, and the results were compared to those of Western blotting. Higher-than-standard-index cutoff values gave optimal sensitivity and specificity. Kalon ELISA was the optimal assay when an index value of 1.5 was used (sensitivity, 91.7%; specificity, 92.4%).


2001 ◽  
Vol 120 (5) ◽  
pp. A136-A137
Author(s):  
K TSAMAKIDES ◽  
E PANOTOPOULOU ◽  
D DIMITROULOPOULOS ◽  
M CHRISTOPOULO ◽  
D XINOPOULOS ◽  
...  

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