scholarly journals Determination of Total Oxidative Stress and Total Antioxidant Capacity before and after the Treatment of Iron-Deficiency Anemia

2013 ◽  
Vol 27 (3) ◽  
pp. 227-230 ◽  
Author(s):  
Halise Akça ◽  
Aziz Polat ◽  
Cemile Koca
Keyword(s):  
Oxidative Stress ◽  
Iron Deficiency ◽  
Antioxidant Capacity ◽  
Iron Deficiency Anemia ◽  
Total Antioxidant Capacity ◽  
Deficiency Anemia ◽  
Before And After ◽  
Total Antioxidant ◽  
Total Oxidative Stress

scholarly journals N-Acetylcysteine Supplementation Controls Total Antioxidant Capacity, Creatine Kinase, Lactate, and Tumor Necrotic Factor-Alpha against Oxidative Stress Induced by Graded Exercise in Sedentary Men

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Donrawee Leelarungrayub ◽  
Raphiphat Khansuwan ◽  
Prapas Pothongsunun ◽  
Jakkrit Klaphajone
Keyword(s):  
Oxidative Stress ◽  
Creatine Kinase ◽  
Antioxidant Capacity ◽  
Muscle Fatigue ◽  
Total Antioxidant Capacity ◽  
Supplement Group ◽  
Graded Exercise ◽  
Before And After ◽  
Total Antioxidant ◽  
Factor Alpha

Aim of this study was to evaluate the effects of short-term (7 days) N-acetylcysteine (NAC) at 1,200 mg daily supplementation on muscle fatigue, maximal oxygen uptake (), total antioxidant capacity (TAC), lactate, creatine kinase (CK), and tumor necrotic factor-alpha (TNF-α). Twenty-nine sedentary men (13 controls; 16 in the supplement group) from a randomized control were included. At before and after supplementation, fatigue index (FI) was evaluated in the quadriceps muscle, and performed a graded exercise treadmill test to induce oxidative stress, and as a measure of . Blood samples were taken before exercise and 20 minutes after it at before and after supplementation, to determine TAC, CK, lactate, and TNF-αlevels. Results showed that FI and increased significantly in the supplement group. After exercise decreased the levels of TAC and increased lactate, CK, and TNF-αof both groups at before supplementation. After supplementation, lactate, CK, and TNF-αlevels significantly increased and TAC decreased after exercise in the control group. Whereas the TAC and lactate levels did not change significantly, but CK and TNF-αincreased significantly in the supplement group. Therefore, this results showed that NAC improved the muscle fatigue, , maintained TAC, controlled lactate production, but had no influence on CK and TNF-α.

Clinical Utility of Total Oxidative Stress and Total Antioxidant Capacity in Childhood Febrile Neutropenia

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Buket Kara ◽  
Fikret Akyurek ◽  
Hilal Akbas ◽  
Kubra Ertan ◽  
Husamettin Vatansev ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Febrile Neutropenia ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Clinical Utility ◽  
Total Antioxidant ◽  
Total Oxidative Stress

scholarly journals The Association between Diabetic Retinopathy and Levels of Ischemia-Modified Albumin, Total Thiol, Total Antioxidant Capacity, and Total Oxidative Stress in Serum and Aqueous Humor

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Kadir Kirboga ◽  
Ayse V. Ozec ◽  
Mustafa Kosker ◽  
Ayhan Dursun ◽  
Mustafa I. Toker ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetic Retinopathy ◽  
Antioxidant Capacity ◽  
Aqueous Humor ◽  
Total Antioxidant Capacity ◽  
Control Group ◽  
Total Thiol ◽  
Median Serum ◽  
Total Antioxidant ◽  
Total Oxidative Stress

Purpose. To investigate the oxidant and antioxidant status of patients with type 2 diabetes mellitus and nonproliferative diabetic retinopathy (DRP).Methods. Forty-four patients who had cataract surgery were enrolled in the study. We included 22 patients with DRP in one group and 22 patients in the control group. Samples of aqueous humor and serum were taken from all patients. Serum and aqueous ischemia-modified albumin (IMA), total thiol, total antioxidant capacity (TAC), and total oxidative stress (TOS) levels were compared in two groups.Results. Median serum IMA levels were 44.80 absorbance units in the DRP group and 40.15 absorbance units in the control group (P=0.031). Median serum total thiol levels in the DRP group were significantly less than those in the control group (3051.13 and 3910.12, resp.,P=0.004). Mean TOS levels in the serum were 2.93 ± 0.19 in the DRP group and 2.61 ± 0.26 in the control group (P=0.039). The differences in mean total thiol, TAC, and TOS levels in the aqueous humor and mean TAC levels in the serum were not statistically significant.Conclusion. IMA, total thiol, and TOS levels in the serum might be useful markers in monitoring the risk of DRP development.

scholarly journals Oxidative stress/antioxidant balance implication in reducing of intra-ocular pressure in patients with stroke, nicergoline therapy and open-angle glaucoma

2019 ◽  
Vol 10 (Vol.10, No.3) ◽  
pp. 259-264 ◽  
Author(s):  
Adriana Elena BULBOACA ◽  
Cristina NICULA 3, ◽  
Angelo BULBOACA ◽  
Mihai BLIDARU ◽  
Paul Mihai BOARESCU ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ischemic Stroke ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Oxidative Stress Parameter ◽  
Positive Effects ◽  
Total Antioxidant ◽  
Total Oxidative Stress

Background: The continue efforts for long term reducing of intraocular pressure (IOP) in patients with open angle glaucoma, focused the attention on those patients who received different therapies, other that topical drugs for IOP reduction, that can influence this parameter.. The aim of this study was to evaluate the IOP, total oxidative stress and anti-oxidant capacity of plasma before and after nicergoline therapy in patients with ischemic stroke and associated open angle glaucoma. Material and method: a group of 35 patients with ischemic stroke and chronic open angle glaucoma (under topical beta-blockers therapy) was studied regarding the values of IOP, total oxidative stress (TOS) and total antioxidant capacity (TAC) before (T1) and after 6 month (T2) of nicergoline therapy. Results: IOP values for both eyes were significantly reduced when the values of T1 examination were compared with those of T2 assessment. The total oxidative stress parameter was also significantly reduced after nicergoline therapy together with increasing of total antioxidant capacity of plasma. Conclusions: besides its positive effects on neuronal metabolism for ischemic stroke patients, nicergoline is able to influence the IOP in patients with open angle glaucoma and to improve the plasmatic oxidative stress/antioxidant balance. By this mechanism nicergoiline can contribute to a neuroprotection and better visual function preservation for these patients, improving their chances to neuro-motor rehabilitation and their quality of life.

scholarly journals Ascorbic Acid Prevents Vascular Endothelial Dysfunction Induced by Electronic Hookah (Waterpipe) Vaping

2021 ◽  
Vol 10 (5) ◽  
Author(s):  
Mary Rezk‐Hanna ◽  
Douglas R. Seals ◽  
Matthew J. Rossman ◽  
Rajat Gupta ◽  
Charlie O. Nettle ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Carbon Monoxide ◽  
Ascorbic Acid ◽  
Endothelial Function ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Plasma Nicotine ◽  
Before And After ◽  
Total Antioxidant ◽  
Exhaled Carbon Monoxide

Background Electronic hookah (e‐hookah) vaping has increased in popularity among youth, who endorse unsubstantiated claims that flavored aerosol is detoxified as it passes through water. However, e‐hookahs deliver nicotine by creating an aerosol of fine and ultrafine particles and other oxidants that may reduce the bioavailability of nitric oxide and impair endothelial function secondary to formation of oxygen‐derived free radicals. Methods and Results We examined the acute effects of e‐hookah vaping on endothelial function, and the extent to which increased oxidative stress contributes to the vaping‐induced vascular impairment. Twenty‐six healthy young adult habitual hookah smokers were invited to vape a 30‐minute e‐hookah session to evaluate the impact on endothelial function measured by brachial artery flow‐mediated dilation (FMD). To test for oxidative stress mediation, plasma total antioxidant capacity levels were measured and the effect of e‐hookah vaping on FMD was examined before and after intravenous infusion of the antioxidant ascorbic acid (n=11). Plasma nicotine and exhaled carbon monoxide levels were measured before and after the vaping session. Measurements were performed before and after sham‐vaping control experiments (n=10). E‐hookah vaping, which increased plasma nicotine (+4.93±0.92 ng/mL, P <0.001; mean±SE) with no changes in exhaled carbon monoxide (−0.15±0.17 ppm; P =0.479), increased mean arterial pressure (11±1 mm Hg, P <0.001) and acutely decreased FMD from 5.79±0.58% to 4.39±0.46% ( P <0.001). Ascorbic acid infusion, which increased plasma total antioxidant capacity 5‐fold, increased FMD at baseline (5.98±0.66% versus 9.46±0.87%, P <0.001), and prevented the acute FMD impairment by e‐hookah vaping (9.46±0.87% versus 8.74±0.84%, P =0.002). All parameters were unchanged during sham studies. Conclusions E‐hookah vaping has adverse effects on vascular function, likely mediated by oxidative stress, which overtime could accelerate development and progression of cardiovascular disease. Registration URL: https://ClinicalTrials.gov . Unique identifier: NCT03690427.

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