The emerging role of selenium metabolic pathways in cancer: New therapeutic targets for cancer

2021 ◽  
Author(s):  
Kalishwaralal Kalimuthu ◽  
Chenicheri K. Keerthana ◽  
Manikandan Mohan ◽  
Jaison Arivalagan ◽  
Johnson Retnaraj Samuel Selvan Christyraj ◽  
...  
Keyword(s):  
Metabolic Pathways ◽  
Therapeutic Targets ◽  
New Therapeutic Targets

scholarly journals The Role of Apoptosis in Detrusor Contractility

2020 ◽  
Vol 24 (Suppl 2) ◽  
pp. 67-71
Author(s):  
Su Jin Kim
Keyword(s):  
Detrusor Overactivity ◽  
Animal Studies ◽  
Voiding Dysfunction ◽  
Therapeutic Targets ◽  
Underlying Mechanism ◽  
Detrusor Contractility ◽  
New Therapeutic Targets ◽  
Human Detrusor

Apoptosis has been found in bladder affected by various types of voiding dysfunction. In animal studies, higher levels of apoptosis were observed in conditions of both detrusor overactivity and underactivity than in normal bladders. However, it has been difficult to establish the exact underlying mechanism of apoptosis in these conditions and to find new therapeutic targets because the causes of voiding dysfunction are diverse and the coexistence of various types of voiding problems is common. Furthermore, the lack of studies of the human detrusor contributes to our incomplete understanding of these issues. Therefore, this revies discuss the role of apoptosis in detrusor contractility based on previous studies.

scholarly journals The Role of Histamine and Histamine Receptors in Mast Cell-Mediated Allergy and Inflammation: The Hunt for New Therapeutic Targets

2018 ◽  
Vol 9 ◽  
Author(s):  
Elden Berla Thangam ◽  
Ebenezer Angel Jemima ◽  
Himadri Singh ◽  
Mirza Saqib Baig ◽  
Mahejibin Khan ◽  
...  
Keyword(s):  
Mast Cell ◽  
Therapeutic Targets ◽  
Histamine Receptors ◽  
New Therapeutic Targets

scholarly journals The role of macrophage polarization on bipolar disorder: Identifying new therapeutic targets

2016 ◽  
Vol 50 (7) ◽  
pp. 618-630 ◽  
Author(s):  
Bruna M Ascoli ◽  
Luiza P Géa ◽  
Rafael Colombo ◽  
Florência M Barbé-Tuana ◽  
Flávio Kapczinski ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Macrophage Polarization ◽  
Therapeutic Targets ◽  
New Therapeutic Targets

New therapeutic targets for antiphospholipid syndrome

Blood ◽  
2007 ◽  
Vol 110 (13) ◽  
pp. 4141-4141
Author(s):  
Tatsuya Atsumi
Keyword(s):  
T Cells ◽  
Antiphospholipid Syndrome ◽  
Cd4 T Cells ◽  
Essential Role ◽  
Therapeutic Targets ◽  
Specific Targeting ◽  
Glycoprotein I ◽  
New Therapeutic Targets ◽  
Anti Phospholipid Syndrome

In this issue of Blood, Yamaguchi and colleagues demonstrated the essential role of the β2-glycoprotein I (β2GPI)/phosphatidylserine complex opsonized by IgG anti-β2GPI antibodies in the proliferation of CD4+ T cells in patients with anti-phospholipid syndrome. Their findings provide novel clues for specific targeting therapies in the affected patients.

Role of progesterone in the prevention of murine miscarriage induced by α-galactosylceramide - New therapeutic targets of progesterone

Placenta ◽  
2021 ◽  
Vol 103 ◽  
pp. 247
Author(s):  
Yasuyuki Negishi ◽  
Yoshimitsu Kuwabara ◽  
Toshiyuki Takeshita ◽  
Rimpei Morita
Keyword(s):  
Therapeutic Targets ◽  
New Therapeutic Targets
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