The prognostic value of long noncoding RNA MEG3 expression in the survival of patients with cancer: A meta‐analysis—response

2019 ◽  
Vol 120 (11) ◽  
pp. 18599-18599 ◽  
Author(s):  
Maryam Moradi Binabaj ◽  
Amirhossein Bahreyni ◽  
Majid Khazaei ◽  
Amir Avan ◽  
Seyed Mahdi Hassanian
Keyword(s):  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Patients With Cancer

The prognostic value of long noncoding RNA MEG3 expression in the survival of patients with cancer: A meta‐analysis

2018 ◽  
Vol 119 (11) ◽  
pp. 9583-9590 ◽  
Author(s):  
Maryam Moradi Binabaj ◽  
Afsane Bahrami ◽  
Amirhossein Bahreyni ◽  
Mojtaba Shafiee ◽  
Farzad Rahmani ◽  
...  
Keyword(s):  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Patients With Cancer

scholarly journals Prognostic Value of Long Noncoding RNA CRNDE as a Novel Biomarker in Solid Cancers: An Updated Systematic Review and Meta-Analysis

2019 ◽  
Vol 10 (11) ◽  
pp. 2386-2396 ◽  
Author(s):  
Yu Zhou ◽  
Rui Wang ◽  
Tian Xu ◽  
Ping Xie ◽  
Yun Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Prognostic Value ◽  
Meta Analysis

scholarly journals Prognostic value of long noncoding RNA ZFAS1 in various carcinomas: a meta-analysis

Oncotarget ◽  
2017 ◽  
Vol 8 (48) ◽  
pp. 84497-84505 ◽  
Author(s):  
Dan Dong ◽  
Zhongyi Mu ◽  
Wei Wang ◽  
Na Xin ◽  
Xiaowen Song ◽  
...  
Keyword(s):  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Prognostic Value ◽  
Meta Analysis

scholarly journals Clinicopathological and prognostic value of long noncoding RNA SNHG7 in cancers: a meta-analysis and bioinformatics

Aging ◽  
2021 ◽  
Author(s):  
June Wang ◽  
Shenlin Du ◽  
Chen Wang ◽  
Zinian Zhu ◽  
Baocheng Xie ◽  
...  
Keyword(s):  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Prognostic Value ◽  
Meta Analysis

scholarly journals Prognostic value and clinical significance of long noncoding RNA CASC2 in human malignancies: a meta-analysis

2018 ◽  
Vol Volume 10 ◽  
pp. 1403-1412 ◽  
Author(s):  
Juan Cai ◽  
Xueliang Zuo ◽  
Zhiqiang Chen ◽  
Wenying Zhao ◽  
Yiping Zhu ◽  
...  
Keyword(s):  
Clinical Significance ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Prognostic Value ◽  
Meta Analysis

scholarly journals Prognostic Value of Long Noncoding RNA SNHG12 in Various Carcinomas: A Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Zhi-Ran Li ◽  
Qin Yang ◽  
Tao Zhou ◽  
Yan-Hua Huang ◽  
Hua-Zhu Zhang ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Prognostic Value ◽  
Bioinformatics Analysis ◽  
Meta Analysis ◽  
Clinical Stage ◽  
Disease Free Survival ◽  
Cochrane Library ◽  
Multiple Cancers

Background. Numerous recent studies suggested that overexpression of the long noncoding RNA small nucleolar RNA host gene 12 (SNHG12) exhibited prooncogenic activity in multiple cancers. However, results regarding the prognostic value of SNHG12 in cancers still remained controversial. Therefore, we conducted a meta-analysis complemented with bioinformatics analysis to elucidate the clinical significance of SNHG12 in cancer patients. Methods. PubMed, Embase, Cochrane Library, Chinese National Knowledge Infrastructure, Wanfang, and Weipu databases were searched for eligible studies until July 2020. Additionally, bioinformatics analysis was applied to verify the results of meta-analysis. Results. Twenty-three related studies consisting of 1389 cancer patients were enrolled in the current meta-analysis. Elevated SNHG12 expression was found to be significantly associated with poor overall survival (OS) ( HR = 1.81 ; 95% CI: 1.53-2.13; P < 0.001 ) and disease-free survival (DFS) ( HR = 1.40 ; 95% CI: 1.12-1.76; P = 0.004 ) in multiple cancers, which were also verified by the results of bioinformatics analysis. Moreover, overexpression of SNHG12 was also related to clinicopathological characteristics including LNM, distant metastasis, high clinical stage, large tumor size, and poor tumor differentiation in diverse types of cancers. Conclusion. The present findings indicated that SNHG12 might act as a novel biomarker for diagnosis or prognosis in human cancers.

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