Daphnetin protects hippocampal neurons from oxygen‐glucose deprivation–induced injury

2018 ◽  
Vol 120 (3) ◽  
pp. 4132-4139 ◽  
Author(s):  
Jin Zhi ◽  
Bin Duan ◽  
Jiwen Pei ◽  
Songdi Wu ◽  
Junli Wei
Keyword(s):  
Hippocampal Neurons ◽  
Glucose Deprivation ◽  
Oxygen Glucose Deprivation

scholarly journals Selenocysteine antagonizes oxygen glucose deprivation-induced damage to hippocampal neurons

2018 ◽  
Vol 13 (8) ◽  
pp. 1433 ◽  
Author(s):  
Xiao-Yan Fu ◽  
Xian-Jun Wang ◽  
Mei-Hong Wang ◽  
Xiao-Ting Fu ◽  
Ya-Jun Hou ◽  
...  
Keyword(s):  
Hippocampal Neurons ◽  
Glucose Deprivation ◽  
Oxygen Glucose Deprivation

scholarly journals hnRNP Q and hnRNP A1 Regulate the Translation of Cofilin in Response to Transient Oxygen–Glucose Deprivation in Hippocampal Neurons

Cells ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 3567
Author(s):  
Sung Wook Kim ◽  
In Kyung Hong ◽  
Mingee Kim ◽  
Yun Seon Song ◽  
Kyong-Tai Kim
Keyword(s):  
Hippocampal Neurons ◽  
Regulatory Mechanism ◽  
Glucose Deprivation ◽  
Protein Aggregates ◽  
Oxygen Glucose Deprivation ◽  
Hnrnp A1 ◽  
Heterogeneous Nuclear Ribonucleoproteins

Protein aggregates of cofilin and actin have been found in neurons under oxygen–glucose deprivation. However, the regulatory mechanism behind the expression of Cfl1 during oxygen–glucose deprivation remains unclear. Here, we found that heterogeneous nuclear ribonucleoproteins (hnRNP) Q and hnRNP A1 regulate the translation of Cfl1 mRNA, and formation of cofilin–actin aggregates. The interaction between hnRNP A1 and Cfl1 mRNA was interrupted by hnRNP Q under normal conditions, while the changes in the expression and localization of hnRNP Q and hnRNP A1 increased such interaction, as did the translation of Cfl1 mRNA under oxygen–glucose deprived conditions. These findings reveal a new translational regulatory mechanism of Cfl1 mRNA in hippocampal neurons under oxygen–glucose deprivation.

Knockdown of TRIM32 Protects Hippocampal Neurons from Oxygen–Glucose Deprivation-Induced Injury

2019 ◽  
Vol 44 (9) ◽  
pp. 2182-2189 ◽  
Author(s):  
Liang Wei ◽  
Jian-shui Zhang ◽  
Sheng-feng Ji ◽  
Hao Xu ◽  
Zhao-hua Zhao ◽  
...  
Keyword(s):  
Hippocampal Neurons ◽  
Glucose Deprivation ◽  
Oxygen Glucose Deprivation

scholarly journals Neuregulin 1/ErbB4 signaling attenuates neuronal cell damage under oxygen-glucose deprivation in primary hippocampal neurons

2019 ◽  
Vol 52 (4) ◽  
pp. 462 ◽  
Author(s):  
Ji-Young Yoo ◽  
Han-Byeol Kim ◽  
Seung-Yeon Yoo ◽  
Hong-Il Yoo ◽  
Dae-Yong Song ◽  
...  
Keyword(s):  
Hippocampal Neurons ◽  
Cell Damage ◽  
Neuronal Cell ◽  
Glucose Deprivation ◽  
Oxygen Glucose Deprivation ◽  
Neuregulin 1 ◽  
Primary Hippocampal Neurons
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