Therapeutic potency of oncolytic virotherapy–induced cancer stem cells targeting in brain tumors, current status, and perspectives

2018 ◽  
Vol 120 (3) ◽  
pp. 2766-2773 ◽  
Author(s):  
Amirhossein Bahreyni ◽  
Elnaz Ghorbani ◽  
Hamid Fuji ◽  
Mikhail Ryzhikov ◽  
Majid Khazaei ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Brain Tumors ◽  
Current Status ◽  
Oncolytic Virotherapy

Abstract 832: Evaluation of relevance of genes expressed in cancer stem cells and under hypoxia in astrocytic brain tumors

2010 ◽  
Author(s):  
Philipp Lehmann ◽  
Muna N. Awad-Masalmeh ◽  
Sandra Sampl ◽  
Johannes Hainfellner ◽  
Matthias Preusser ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Brain Tumors

Drug repurposing towards targeting cancer stem cells in pediatric brain tumors

2020 ◽  
Vol 39 (1) ◽  
pp. 127-148 ◽  
Author(s):  
Hisham F. Bahmad ◽  
Mohamad K. Elajami ◽  
Talal El Zarif ◽  
Jolie Bou-Gharios ◽  
Tamara Abou-Antoun ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Brain Tumors ◽  
Drug Repurposing ◽  
Pediatric Brain Tumors ◽  
Pediatric Brain

scholarly journals Targeting pediatric cancer stem cells with oncolytic virotherapy

2012 ◽  
Vol 71 (2-4) ◽  
pp. 500-510 ◽  
Author(s):  
Gregory K. Friedman ◽  
Kevin A. Cassady ◽  
Elizabeth A. Beierle ◽  
James M. Markert ◽  
G. Yancey Gillespie
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Pediatric Cancer ◽  
Oncolytic Virotherapy

scholarly journals The Role of MicroRNAs in the Regulation of Gastric Cancer Stem Cells: A Meta-Analysis of the Current Status

2019 ◽  
Vol 8 (5) ◽  
pp. 639 ◽  
Author(s):  
Vitalba Ruggieri ◽  
Sabino Russi ◽  
Pietro Zoppoli ◽  
Francesco La Rocca ◽  
Tiziana Angrisano ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Stem Cells ◽  
Cancer Stem Cells ◽  
Meta Analysis ◽  
Current Status ◽  
Cancer Drug ◽  
Cellular Processes ◽  
Cancer Drug Resistance ◽  
Gastric Cancer Stem Cells

Gastric cancer (GC) remains one of the major causes of cancer-related mortality worldwide. As for other types of cancers, several limitations to the success of current therapeutic GC treatments may be due to cancer drug resistance that leads to tumor recurrence and metastasis. Increasing evidence suggests that cancer stem cells (CSCs) are among the major causative factors of cancer treatment failure. The research of molecular CSC mechanisms and the regulation of their properties have been intensively studied. To date, molecular gastric cancer stem cell (GCSC) characterization remains largely incomplete. Among the GCSC-targeting approaches to overcome tumor progression, recent studies have focused their attention on microRNA (miRNA). The miRNAs are short non-coding RNAs which play an important role in the regulation of numerous cellular processes through the modulation of their target gene expression. In this review, we summarize and discuss recent findings on the role of miRNAs in GCSC regulation. In addition, we perform a meta-analysis aimed to identify novel miRNAs involved in GCSC homeostasis.

scholarly journals Cancer stem cells and brain tumors

2008 ◽  
Vol 10 (5) ◽  
pp. 262-267 ◽  
Author(s):  
Ana Pérez-Castillo ◽  
Diana Aguilar-Morante ◽  
José A. Morales-García ◽  
Jorge Dorado
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Brain Tumors

Role of cancer stem cells in brain tumors

BioMedicine ◽  
2012 ◽  
Vol 2 (3) ◽  
pp. 84-91 ◽  
Author(s):  
Ya-Huey Chen ◽  
Mien-Chie Hung ◽  
Woei-Cherng Shyu
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Brain Tumors
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