PlGF knockdown induced apoptosis through Wnt signaling pathway in gastric cancer stem cells

2018 ◽  
Vol 120 (3) ◽  
pp. 3268-3276 ◽  
Author(s):  
Hassan Akrami ◽  
Kiumars Mehdizadeh ◽  
Behrouz Moradi ◽  
Diba Borzabadi Farahani ◽  
Kamran Mansouri ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Stem Cells ◽  
Cancer Stem Cells ◽  
Wnt Signaling ◽  
Signaling Pathway ◽  
Wnt Signaling Pathway ◽  
Gastric Cancer Stem Cells ◽  
Induced Apoptosis

scholarly journals Wnt-signaling pathway in pathogenesis of glioblastoma multiforme

2019 ◽  
Vol 5 (4) ◽  
pp. 94-103
Author(s):  
Yu. D. Vasilets ◽  
N. E. Arnotskaya ◽  
I. A. Kudryavtsev ◽  
V. E. Shevchenko
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Wnt Signaling ◽  
Signaling Pathway ◽  
Wnt Signaling Pathway ◽  
Biological Processes ◽  
Current Standard ◽  
Immune Resistance ◽  
Oncogenic Driver ◽  
And Migration

The Wnt-signaling pathway regulates various biological processes, such as embryonic development, self-renewal, proliferation, differentiation and migration of stem cells. The Wnt-signaling is involved in tumor progression by aberrant activation in stem-like cells, called cancer stem cells, in different kinds of tumor, including multiform glioblastoma. The Wnt-signaling promotes stemness, invasion, metastasis, therapeutic and immune resistance of cancer stem cells in multiform glioblastoma. To summarize, targeting the Wnt-signaling pathway as an oncogenic driver is the future hope for effective therapy of glioblastoma for which current standard therapy is not effective.In this review, we focused on functions of the Wnt-signaling in cancer stem cells and involvement of the Wnt-signaling pathway in gliomagenesis.

Ibuprofen reduces cell proliferation through inhibiting Wnt/β catenin signaling pathway in gastric cancer stem cells

2018 ◽  
Vol 42 (8) ◽  
pp. 949-958 ◽  
Author(s):  
Hassan Akrami ◽  
Behrouz Moradi ◽  
Diba Borzabadi Farahani ◽  
Kiumars Mehdizadeh
Keyword(s):  
Gastric Cancer ◽  
Stem Cells ◽  
Cell Proliferation ◽  
Cancer Stem Cells ◽  
Signaling Pathway ◽  
Gastric Cancer Stem Cells

scholarly journals Proteins of the Wnt signaling pathway as targets for the regulation of CD133+ cancer stem cells in glioblastoma

2019 ◽  
Author(s):  
Valery Shevchenko ◽  
Nataliya Arnotskaya ◽  
Maria Korneyko ◽  
Sergry Zaytsev ◽  
Yuriy Khotimchenko ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Wnt Signaling ◽  
Signaling Pathway ◽  
Wnt Signaling Pathway

scholarly journals Wnt-signaling pathway in the cancer stem cells of glioblastoma

2018 ◽  
Vol 29 ◽  
pp. vi26-vi27
Author(s):  
I.S. Bryukhovetskiy ◽  
V. Shevchenko ◽  
Y. Khotimchenko
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Wnt Signaling ◽  
Signaling Pathway ◽  
Wnt Signaling Pathway
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