The effect of combined pulsed wave low‐level laser therapy and mesenchymal stem cell‐conditioned medium on the healing of an infected wound with methicillin‐resistant Staphylococcal aureus in diabetic rats

2018 ◽  
Vol 119 (7) ◽  
pp. 5788-5797 ◽  
Author(s):  
Reza Kouhkheil ◽  
Mohammadjavad Fridoni ◽  
Abbas Piryaei ◽  
Soudabeh Taheri ◽  
Alireza S. Chirani ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Conditioned Medium ◽  
Laser Therapy ◽  
Diabetic Rats ◽  
Low Level Laser Therapy ◽  
Infected Wound ◽  
Level Laser ◽  
Staphylococcal Aureus ◽  
Cell Conditioned Medium

Mesenchymal stem cell-conditioned medium facilitates angiogenesis and fracture healing in diabetic rats

2011 ◽  
Vol 6 (7) ◽  
pp. 559-569 ◽  
Author(s):  
Chien-Yuan Wang ◽  
Hsiao-Bai Yang ◽  
Han-Shui Hsu ◽  
Ling-Lan Chen ◽  
Chih-Chien Tsai ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Fracture Healing ◽  
Conditioned Medium ◽  
Diabetic Rats ◽  
Cell Conditioned Medium

Effect of low-level laser therapy on mesenchymal stem cell proliferation: a systematic review

2015 ◽  
Vol 30 (8) ◽  
pp. 2189-2194 ◽  
Author(s):  
Fernanda Ginani ◽  
Diego Moura Soares ◽  
Mardem Portela e Vasconcelos Barreto ◽  
Carlos Augusto Galvão Barboza
Keyword(s):  
Systematic Review ◽  
Cell Proliferation ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Laser Therapy ◽  
Low Level Laser Therapy ◽  
Stem Cell Proliferation ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Wound-healing effects of low-level laser therapy in diabetic rats involve the modulation of MMP-2 and MMP-9 and the redistribution of collagen types I and III

2013 ◽  
Vol 15 (4) ◽  
pp. 210-216 ◽  
Author(s):  
Andreia Aparecida Da Silva ◽  
Ernesto Cesar Pinto Leal-Junior ◽  
Ana Carolina Araruna Alves ◽  
Caroline Sobral Rambo ◽  
Solange Almeida Dos Santos ◽  
...  
Keyword(s):  
Wound Healing ◽  
Laser Therapy ◽  
Diabetic Rats ◽  
Low Level Laser Therapy ◽  
Collagen Types ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Mesenchymal Stem Cell Conditioned Medium as Good as Methyl Prednisolone in Decreasing Levels of Interleukin 10 and The Degree of Pulmonary Vasculitis in Lupus Mice

2021 ◽  
Vol 20 (2) ◽  
pp. 426-430
Author(s):  
Nurhasan Agung Prabowo ◽  
Zainal Arifin Adnan ◽  
Arief Nurudhin ◽  
Yulyani Werdiningsih ◽  
Kukuh Prasetyo
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Conditioned Medium ◽  
Interleukin 10 ◽  
Control Group ◽  
Standard Drug ◽  
Methyl Prednisolone ◽  
Pulmonary Vasculitis ◽  
Anti Inflammatory ◽  
Cell Conditioned Medium

Background: Systemic lupus erythematosus is a chronic autoimmune disease that affects target organs. mesenchymal stem cell conditioned medium has immunosuppressive, anti-inflammatory, and immunoregulatory properties in lupus. Methyl prednisolone is a standard drug for lupus with immunosuppressive and anti-inflammatory properties. This study aims to compare the therapeutic effect of mesenchymal stem cell conditioned medium administration compared to methyl prednisolone on interleukin 10 levels and the degree of pulmonary vasculitis of lupus mice. Methods: The subjects were 24 female mice of Mus musculus Balb/C strain, which were categorized into 4 groups of 8 mice, i.e. the control group receiving 0.5 cc of 0.9% NaCl injection and placebo, the lupus group receiving 0.5 cc of pristane injection and placebo, and the treatment mesenchymal stem cell conditioned medium group receiving 0.5 cc pristane injection and mesenchymal stem cell conditioned medium 0,5 cc, and methylprednisolone group receiving 0,5 cc pristiane injection and methylprednisolone p.o 1,5 mg/kgbodyweight. After 24 days the mice were terminated and kidney and blood samples were taken. Statistical analysis was performed using ANOVA test followed by independent T-test. The p value was considered significant when the p < 0.05. Results: The study showed that there was no difference on the levels of interleukin level10 among mesenchymal stem cell conditioned medium goup and methyl prednisolone group (CM = 5,94 ± 2,49 pg/mL, mp = 5,86+1,73 pg/mL; p = 1) and the degree of pulmonary vasculitis (CM= 1,94 ± 0,25, MP=1,89+ 0,11 pg/ml; p = 0.667). Mesenchymal stem cell conditioned medium as good as methyl prednisolone in decreasing levels of interleukin 10 and the degree of pulmonary vasculitis in lupus mice. Conclusion: Mesenchymal stem cell conditioned medium as good as methyl prednisolone in decreasing levels of interleukin 10 and the degree of pulmonary vasculitis in lupus mice Bangladesh Journal of Medical Science Vol.20(2) 2021 p.426-430

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