Efficacy comparison of traditional Chinese medicine LQ versus gemcitabine in a mouse model of pancreatic cancer

2013 ◽  
Vol 114 (9) ◽  
pp. 2131-2137 ◽  
Author(s):  
Lei Zhang ◽  
Chengyu Wu ◽  
Yong Zhang ◽  
Fang Liu ◽  
Ming Zhao ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Mouse Model

scholarly journals Effect of Rhizoma Paridis saponin on the pain behavior in a mouse model of cancer pain

RSC Advances ◽  
2018 ◽  
Vol 8 (31) ◽  
pp. 17060-17072 ◽  
Author(s):  
Genbei Wang ◽  
Yuanxue Liu ◽  
Yu Wang ◽  
Wenyuan Gao
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Mouse Model ◽  
Cancer Pain ◽  
Pain Behavior ◽  
Cancer Drug ◽  
Anti Cancer

Rhizoma Paridis saponins (RPS) as active parts ofP. polyphyllaSmith var.yunnanensishas been used as an anti-cancer drug in traditional Chinese medicine.

scholarly journals Survival Benefits of Western and Traditional Chinese Medicine Treatment for Patients With Pancreatic Cancer

Medicine ◽  
2015 ◽  
Vol 94 (26) ◽  
pp. e1008 ◽  
Author(s):  
Xue Yang ◽  
Jian Hao ◽  
Cui-Hong Zhu ◽  
Yang-Yang Niu ◽  
Xiu-Li Ding ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Traditional Chinese Medicine Treatment ◽  
Chinese Medicine Treatment

Traditional Chinese medicine may be further explored as candidate drugs for pancreatic cancer: A review

2020 ◽  
Author(s):  
Yue Gao ◽  
Shiyu Chen ◽  
Jiayi Sun ◽  
Siyu Su ◽  
Dong Yang ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine

scholarly journals Traditional Chinese Medicine QPYF as Preventive Treatment forClostridium difficileAssociated Diarrhea in a Mouse Model

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Guo Ya-Nan ◽  
Wang Jun ◽  
Zhang Hao-Jun ◽  
Jia Hong-Bing ◽  
Li Ping ◽  
...  
Keyword(s):  
Weight Loss ◽  
Chinese Medicine ◽  
Clostridium Difficile ◽  
Traditional Chinese Medicine ◽  
Mouse Model ◽  
Disease Activity ◽  
Activity Index ◽  
Disease Activity Index ◽  
Good Effect ◽  
Model Control

Traditional Chinese medicine QPYF has a good effect for treating antibiotic-associated diarrhea in clinical practice. The aim of this study is to test its efficacy to preventClostridium difficileassociated diarrhea (CDAD) in a mouse model. C57BL/6 mice were infected withClostridium difficileVPI 10463 after exposure to antimicrobial mixture. QPYF was administered from 7 days prior toClostridium difficileinfection to 20 days after infection, and its effect was compared with no treatment and receiving placebo. The mice were monitored for 20 days and the percent survival, disease activity index, weight loss, colon histopathology, and the levels of toxins in the feces were measured. The expressions of TNFα, MCP-1, NF-κB p65, and phospho-NF-κB p65 in the colon were presented by immunohistochemistry. The survival rate of QPYF group (93.75%) was higher than that of model control group (65%). The mice treated with QPYF had a lower weight loss and disease activity index, compared to the mice with placebo. A significantly lower level of histopathology scores, toxins in the feces, and TNFα, MCP-1, NF-κB p65, and phospho-NF-κB p65 were detected for QPYF-treated mice. Traditional Chinese medicine QPYF showed a good preventive effect for CDAD in a mouse model.

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