Enhanced phosphoinositide metabolism in colorectal carcinoma cells derived from familial adenomatous polyposis patients

1994 ◽  
Vol 55 (4) ◽  
pp. 477-485 ◽  
Author(s):  
Miwako K. Homma ◽  
Yoshimi Homma ◽  
Masayoshi Namba ◽  
Yasuhito Yuasa
2017 ◽  
Vol 5 (1-2) ◽  
pp. 21-25
Author(s):  
B.R. Joshi

An unusual case of multiple round filling defects in colon in a patient with family history of rectal malignancy and its pathogenesis has been described. Family history may not be present in 25%. Usually there is family history of polyp or colorectal carcinoma at 40 years or younger. The young patient may suffer from unexplained rectal bleeding, diarrhea, abdominal pain. Some may be asymptomatic until they develop carcinoma.Nepal Journal of Radiology Vol.5(1-2) 2015: 21-25


2008 ◽  
Vol 22 (7) ◽  
pp. 634-636 ◽  
Author(s):  
Melanie D Beaton ◽  
Brian Taylor ◽  
David Driman ◽  
Peter Ainsworth ◽  
Paul C Adams

Attenuated familial adenomatous polyposis (AFAP) is a rare but well-established cause of colorectal carcinoma and multiple polyps. The present paper describes a case of a woman diagnosed with colorectal cancer at 34 years of age and subsequently found to have AFAP by genetic testing. During infancy, the patient underwent surgical correction of esophageal atresia with colonic interposition. While she had developed adenomatous polyps in her native cecum, there was no evidence of polyps or cancer in the segment of large intestine interposed between her upper esophagus and stomach. Therefore, various environmental differences between the upper and lower gastrointestinal tract may play a role in the expression of AFAP phenotype.


PEDIATRICS ◽  
2016 ◽  
Vol 137 (Supplement 3) ◽  
pp. 418A-418A
Author(s):  
Mariecel Pilapil ◽  
Toni Webster ◽  
Steven ◽  
Alexandra Cohen ◽  
Ravi Sharaf

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