Anti-Proliferative Effects of Evodiamine on Human Thyroid Cancer Cell Line ARO

2010 ◽  
Vol 110 (6) ◽  
pp. 1495-1503 ◽  
Author(s):  
Meng-Ching Chen ◽  
Ching-Han Yu ◽  
Shyi-Wu Wang ◽  
Hsiao-Fung Pu ◽  
Shu-Fen Kan ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Human Thyroid ◽  
Thyroid Cancer Cell ◽  
Thyroid Cancer Cell Line

scholarly journals Regulation of Uptake of 18F-FDG by a Follicular Human Thyroid Cancer Cell Line with Mutation-Activated K-Ras

2009 ◽  
Vol 50 (8) ◽  
pp. 1364-1370 ◽  
Author(s):  
O. Prante ◽  
S. Maschauer ◽  
V. Fremont ◽  
J. Reinfelder ◽  
R. Stoehr ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Human Thyroid ◽  
Thyroid Cancer Cell ◽  
Thyroid Cancer Cell Line ◽  
18F Fdg

scholarly journals Characterization of a thyroid hormone-mediated short-loop feedback control of TSH receptor gene in an anaplastic human thyroid cancer cell line

2002 ◽  
Vol 175 (2) ◽  
pp. 459-465 ◽  
Author(s):  
ST Chen ◽  
JD Lin ◽  
KH Lin
Keyword(s):  
Gene Expression ◽  
Thyroid Cancer ◽  
Thyroid Hormone ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Human Thyroid ◽  
Thyroid Cancer Cell ◽  
Thyroid Cancer Cell Line ◽  
Tshr Gene

The expression of TSH receptor (TSHR) gene is frequently lost in thyroid cancers during the process of dedifferentiation that involves perturbation of several nuclear transcription factors. We have established that thyroid hormone receptor beta1 (TRbeta1) is associated with the loss of TSHR gene expression in an anaplastic human thyroid cancer cell line, ARO. To demonstrate that TRbeta1 regulates TSHR gene expression, we performed electrophoresis mobility shift and 3,5,3'-triiodothyronine (T3) transactivation assays. As expected, TRbeta1 bound the synthesized oligomer containing TSHR promoter sequence by heterodimerizing with retinoid X receptor. When a chimeric reporter pTRCAT5'-146 enclosing the minimal TSHR promoter was applied for T3 transactivation assay, two TRbeta1-overexpressing transfectants of ARO cells (ARO1 and ARO2) demonstrated higher basal activity than their parental cells. Consequentially, T3 suppressed the reporter gene activity only in ARO1 and ARO2, but not in ARO cells. A point mutation creating a cAMP response element (CRE) in the reporter pTRCAT5'-146 CRE led to T3-induced suppression of the reporter gene in ARO cells without changing the basal or T3-induced activities in ARO1 and ARO2 cells. We conclude that the regulatory effect of T3 on TSHR gene expression is TR- and promoter DNA sequence-determined.

Autocrine role of insulin-like growth factor (IGF)-I in a human thyroid cancer cell line

1992 ◽  
Vol 28 (11) ◽  
pp. 1904-1909 ◽  
Author(s):  
Noritaka Onoda ◽  
Eiji Ohmura ◽  
Toshio Tsushima ◽  
Yoshito Ohba ◽  
Naoya Emoto ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Growth Factor ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Human Thyroid ◽  
Thyroid Cancer Cell ◽  
Thyroid Cancer Cell Line ◽  
Igf I

The flavonoid quercetin reduces cell migration and increases NIS and E-cadherin mRNA in the human thyroid cancer cell line BCPAP

2021 ◽  
pp. 111266
Author(s):  
Carlos Frederico Lima Gonçalves ◽  
Fabio Hecht ◽  
Juliana Cazarin ◽  
Rodrigo Soares Fortunato ◽  
Mario Vaisman ◽  
...  
Keyword(s):  
Cell Migration ◽  
Thyroid Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Human Thyroid ◽  
Thyroid Cancer Cell ◽  
Thyroid Cancer Cell Line ◽  
Flavonoid Quercetin ◽  
E Cadherin

Effects of melatonin on the toxicity and proliferation of human anaplastic thyroid cancer cell line

2021 ◽  
Vol 123 (3) ◽  
pp. 151700
Author(s):  
Marjan Ghorbani-Anarkooli ◽  
Sara Dabirian ◽  
Adib Zendedel ◽  
Hasan Moladoust ◽  
Mohammad hadi Bahadori
Keyword(s):  
Thyroid Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Anaplastic Thyroid Cancer ◽  
Thyroid Cancer Cell ◽  
Thyroid Cancer Cell Line
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