Hourglass ballooning of the apheresis kit blood filter

2020 ◽  
Vol 35 (4) ◽  
pp. 376-377
Author(s):  
John Gnanaraj ◽  
Charumathy Arjunan ◽  
Abhishekh Basavarajegowda
Keyword(s):  
Blood Filter

scholarly journals The acoustic filter: An ultrasonic blood filter for the heart-lung machine

1992 ◽  
Vol 104 (6) ◽  
pp. 1647-1653 ◽  
Author(s):  
Karl Q. Schwarz ◽  
Charles C. Church ◽  
Peter Serrino ◽  
Richard S. Meltzer
Keyword(s):  
Blood Filter ◽  
Heart Lung Machine ◽  
Lung Machine

Magnetic resonance imaging velocimetry of fluid flow in a clinical blood filter

AIChE Journal ◽  
2005 ◽  
Vol 51 (9) ◽  
pp. 2396-2401 ◽  
Author(s):  
Frank Heese ◽  
Philip Robson ◽  
Laurie Hall
Keyword(s):  
Magnetic Resonance Imaging ◽  
Fluid Flow ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Blood Filter

Evaluation of a new whole-blood filter that allows preparation of platelet concentrates by platelet-rich plasma methods

Transfusion ◽  
2003 ◽  
Vol 43 (12) ◽  
pp. 1723-1728 ◽  
Author(s):  
Maria L. Lozano ◽  
Elena Pérez-Ceballos ◽  
Jose Rivera ◽  
Dragica Paunovic ◽  
Maria J. Candela ◽  
...  
Keyword(s):  
Whole Blood ◽  
Platelet Rich Plasma ◽  
Platelet Concentrates ◽  
Blood Filter ◽  
Plasma Methods

scholarly journals In vitro elimination of anti-infective drugs by the Seraph® 100 Microbind® affinity blood filter

2020 ◽  
Author(s):  
Julius J Schmidt ◽  
Gabriele Eden ◽  
Malin-Theres Seffer ◽  
Manuela Winkler ◽  
Jan T Kielstein
Keyword(s):  
In Vitro Study ◽  
The European Union ◽  
Human Donor ◽  
Blood Filter ◽  
Pathogen Load ◽  
Drug Concentrations ◽  
First Pass ◽  
Ultra High Molecular Weight ◽  
Donor Plasma

Abstract Background In August 2019, the European Union licensed the first ever haemoperfusion device aimed to reduce pathogens in the blood. The core of the adsorber consists of ultra-high molecular weight polyethylene beads with endpoint-attached heparin. These beads utilize pathogen inherent adhesion mechanisms to reduce pathogen load. So far, it is unknown whether the device has an effect on anti-infective drug concentrations. The aim of this study was to investigate the in vitro adsorption of multiple anti-infective drugs from human plasma. Methods In this in vitro study, 18 anti-infective drugs were administered to human donor plasma and pumped through the heparin-coated pathogen adsorber (Seraph® 100 Microbind®Affinity Blood Filter; ExThera Medical Corp., Martinez, CA, USA) at a plasma flow rate of 250 mL/min for 60 min. Pre- and post-adsorber plasma samples were quantified after 5, 15, 30 and 60 min. Results We found a reduction ratio (RR) in anti-infective plasma levels between −1% and 62%. This decrease occurred mainly in the first 5 min of the experiment (RR0–5 −4 to 62%). Mean plasma clearance rates ranged between –11.93 mL/min (fluconazole) and 4.86 mL/min (clindamycin). The highest RRs were measured for aminoglycosides (tobramycin 62% and gentamycin 59%). Conclusions The elimination of anti-infective drugs by the Seraph is neglectable in all but 2 of 18 of the investigated substances. Aminoglycosides may be adsorbed by the device during their first pass.

Elimination of Staphylococcus aureus from the bloodstream using a novel biomimetic sorbent haemoperfusion device

2020 ◽  
Vol 13 (8) ◽  
pp. e235262
Author(s):  
Malin-Theres Seffer ◽  
Gabriele Eden ◽  
Susanne Engelmann ◽  
Jan T Kielstein
Keyword(s):  
Staphylococcus Aureus ◽  
Haemodialysis Patient ◽  
Bacterial Load ◽  
Ultrahigh Molecular Weight Polyethylene ◽  
Blood Stream ◽  
Chronic Haemodialysis ◽  
The European Union ◽  
Blood Filter ◽  
First Case ◽  
Ultrahigh Molecular Weight

Removal of bacteria from the blood by means of extracorporeal techniques has been attempted for decades. In late 2019, the European Union licensed the first ever haemoperfusion device for removal of bacteria from the blood. The active ingredient of Seraph 100 Microbind Affinity Blood Filter is ultrahigh molecular weight polyethylene beads with endpoint-attached heparin. Bacteria have been shown to bind to heparin as they would usually do to the heparan sulfate on the cell surface, thereby being removed from the blood stream. We describe the first case of a female chronic haemodialysis patient in which this device was clinically used for a Staphylococcus aureus infection that persisted for 4 days despite antibiotic therapy. After a single treatment, the bacterial load decreased and the blood cultures at the end of a 4 hour haemoperfusion exhibited no bacterial growth.

scholarly journals Treatment for Severe Coronavirus Disease 2019 With the Seraph-100 Microbind Affinity Blood Filter

2020 ◽  
Vol 2 (8) ◽  
pp. e0180
Author(s):  
Stephen W. Olson ◽  
James D. Oliver ◽  
Jacob Collen ◽  
Jessica Bunin ◽  
Todd D. Gleeson ◽  
...  
Keyword(s):  
Blood Filter

Monocyte enrichment of mononuclear apheresis preparations with a multistep back-flush procedure on a cord blood filter

Transfusion ◽  
2005 ◽  
Vol 45 (3) ◽  
pp. 433-439 ◽  
Author(s):  
Stephen J. Wagner ◽  
Andrew Myrup ◽  
Yanwen Xu ◽  
M. Susan Walker ◽  
Craig Welbon ◽  
...  
Keyword(s):  
Cord Blood ◽  
Blood Filter

scholarly journals Nested PCR detection of malaria directly using blood filter paper samples from epidemiological surveys

2014 ◽  
Vol 13 (1) ◽  
pp. 175 ◽  
Author(s):  
Peipei Li ◽  
Zhenjun Zhao ◽  
Ying Wang ◽  
Hua Xing ◽  
Daniel M Parker ◽  
...  
Keyword(s):  
Filter Paper ◽  
Nested Pcr ◽  
Pcr Detection ◽  
Blood Filter ◽  
Epidemiological Surveys

Twelve different enzyme assays on dried-blood filter paper samples for detection of patients with selected inherited lysosomal storage diseases

2006 ◽  
Vol 372 (1-2) ◽  
pp. 98-102 ◽  
Author(s):  
Gabriel Civallero ◽  
Kristiane Michelin ◽  
Jurema de Mari ◽  
Marli Viapiana ◽  
Maira Burin ◽  
...  
Keyword(s):  
Filter Paper ◽  
Lysosomal Storage Diseases ◽  
Enzyme Assays ◽  
Lysosomal Storage ◽  
Storage Diseases ◽  
Blood Filter
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