High-volume plasma exchange in a patient with acute liver failure due to non-exertional heat stroke in a sauna

2014 ◽  
Vol 29 (5) ◽  
pp. 281-283 ◽  
Author(s):  
Kuan-Jung Chen ◽  
Tso-Hsiao Chen ◽  
Yuh-Mou Sue ◽  
Tzay-Jinn Chen ◽  
Chung-Yi Cheng
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Plasma Exchange ◽  
Heat Stroke ◽  
High Volume ◽  
Exertional Heat Stroke

scholarly journals A Case of Exertional Heat Stroke Complicated by Hypoxic Hepatitis

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Bertram K. Woitok ◽  
Shawki Bahmad ◽  
Gregor Lindner
Keyword(s):  
Supportive Care ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Multiorgan Failure ◽  
Heat Stroke ◽  
Exertional Heat Stroke ◽  
Hypoxic Hepatitis ◽  
Threatening Condition ◽  
Life Threatening ◽  
Delayed Referral

Background.Exertional heat stroke is a life-threatening condition often complicated by multiorgan failure. We hereby present a case of a 25-year-old male presenting with syncope after a 10  km run in 28°C outside temperature who developed acute liver failure. Case Presentation. Initial temperature was found to be 41.1°C, and cooling measures were rapidly applied. He suffered from acute renal failure and rhabdomyolysis and proceeded to acute liver failure (ASAT 6100 U/l and ALAT 6561 U/l) due to hypoxic hepatitis on day 3. He did not meet criteria for emergency liver transplantation and recovered on supportive care. Conclusions. Acute liver failure due to heat stroke is a life-threatening condition with often delayed onset, which nevertheless resolves on supportive care in the majority of cases; thus, a delayed referral to transplant seems to be reasonable.

scholarly journals Exertional heat stroke associated with acute liver failure in a young refugee. Implications in the era of social-economic crisis

2019 ◽  
Vol 28 (3) ◽  
pp. 364-364
Author(s):  
Dimitrios S. Politis ◽  
Gerasimos Baltagiannis ◽  
Nikolaos Tzampouras ◽  
George N Kalambokis ◽  
Vasileios Koulouras ◽  
...  
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Economic Crisis ◽  
Social Economic ◽  
Heat Stroke ◽  
Exertional Heat Stroke

.

scholarly journals Therapeutic plasma exchange in children with acute liver failure (ALF): is it time for incorporation into the ALF armamentarium?

2021 ◽  
Author(s):  
Emma C. Alexander ◽  
Akash Deep
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Plasma Exchange ◽  
Controlled Trial ◽  
High Volume ◽  
Systemic Circulation ◽  
Liver Support ◽  
Extracorporeal Liver Support ◽  
Randomised Controlled ◽  
Liver Assist Devices

AbstractPaediatric acute liver failure (PALF) is a rare but devastating condition with high mortality. An exaggerated inflammatory response is now recognised as pivotal in the pathogenesis and prognosis of ALF, with cytokine spill from the liver to systemic circulation implicated in development of multi-organ failure associated with ALF. With advances in medical management, especially critical care, there is an increasing trend towards spontaneous liver regeneration, averting the need for emergency liver transplantation or providing stability to the patient awaiting a graft. Hence, research is ongoing for therapies, including extracorporeal liver support devices, that can bridge patients to transplant or spontaneous liver recovery. Considering the immune-related pathogenesis and inflammatory phenotype of ALF, plasma exchange serves as an ideal liver assist device as it performs both the excretory and synthetic functions of the liver and, in addition, works as an immunomodulatory therapy by suppressing the early innate immune response in ALF. After a recent randomised controlled trial in adults demonstrated a beneficial effect of high-volume plasma exchange on clinical outcomes, this therapy was incorporated in European Association for the Study of Liver (EASL) recommendations for managing adult patients with ALF, but no guidelines exist for PALF. In this review, we discuss rationale, timing, practicalities, and existing evidence regarding the use of plasma exchange as an immunomodulatory treatment in PALF. We discuss controversies in delivery of this therapy as an extracorporeal device, and practicalities of use of plasma exchange as a ‘hybrid’ therapy alongside other extracorporeal liver assist devices, before finally reviewing outstanding research questions for the future.

Acute Liver Failure: A Rare Primary Sequela of Exertional Heat Stroke

2018 ◽  
Vol 113 (Supplement) ◽  
pp. S1277
Author(s):  
Lindsay Clarke ◽  
Daniel Szvarca ◽  
Danielle Davison ◽  
Bedoor Alabbas ◽  
Marie Borum
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Heat Stroke ◽  
Exertional Heat Stroke

Exertional Heat Stroke in a Young Athlete Resulting in Acute Liver Failure

2016 ◽  
Vol 63 (4) ◽  
pp. e75-e76 ◽  
Author(s):  
Jacob A. Kurowski ◽  
Henry C. Lin ◽  
Saeed Mohammad ◽  
Steven Krug ◽  
Estella M. Alonso
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Heat Stroke ◽  
Young Athlete ◽  
Exertional Heat Stroke

scholarly journals High Volume Plasma Exchange in Acute Liver Failure

2021 ◽  
Author(s):  
A. Tharwani ◽  
A. Bhardwaj ◽  
M. Aggarwal ◽  
H. Einchenlaub ◽  
K. Kommaraju ◽  
...  
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Plasma Exchange ◽  
High Volume

Acute Liver Failure Complicating Exertional Heat Stroke

2015 ◽  
Vol 14 (1) ◽  
pp. 49-50 ◽  
Author(s):  
Cécile Salathé ◽  
Cyril Pellaton ◽  
Pierre-Nicolas Carron ◽  
Marcos Coronado ◽  
Lucas Liaudet
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Heat Stroke ◽  
Exertional Heat Stroke
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