Comparative toxicity studies on bromochloroacetate, dibromoacetate, and bromodichloroacetate in J774A.1 macrophages: Roles of superoxide anion and protein carbonyl compounds

2018 ◽  
Vol 32 (4) ◽  
pp. e22045
Author(s):  
Ezdihar A. Hassoun ◽  
Xiaoqun Zeng
Keyword(s):  
Carbonyl Compounds ◽  
Superoxide Anion ◽  
Protein Carbonyl ◽  
Toxicity Studies ◽  
Comparative Toxicity ◽  
Protein Carbonyl Compounds

Comparative toxicity of hydrogen peroxide, hydroxyl radicals, and superoxide anion to Escherichia coli

2003 ◽  
Vol 7 (4) ◽  
pp. 961-968 ◽  
Author(s):  
Richard J. Watts ◽  
Diana Washington ◽  
Jimmy Howsawkeng ◽  
Frank J. Loge ◽  
Amy L. Teel
Keyword(s):  
Escherichia Coli ◽  
Hydrogen Peroxide ◽  
Hydroxyl Radicals ◽  
Superoxide Anion ◽  
Comparative Toxicity

Acupuncture promotes expression of Hsp84/86 and delays brain ageing in SAMP8 mice

2019 ◽  
Vol 37 (6) ◽  
pp. 340-347 ◽  
Author(s):  
Shichen Chang ◽  
Xuanyang Guo ◽  
Guomin Li ◽  
Xuezhu Zhang ◽  
Jing Li ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Protein Expression ◽  
Success Rate ◽  
Superoxide Anion ◽  
Acupuncture Treatment ◽  
Protein Carbonyl ◽  
Morris Water Maze Test ◽  
Brain Ageing ◽  
Mrna And Protein Expression ◽  
Samp8 Mice

Objective: To study the effects of acupuncture on expression of heat shock protein (Hsp) 84 and 86, and brain ageing, in the senescence accelerated mouse prone 8 (SAMP8) model of Alzheimer’s disease. Methods: 7-month-old male senescence resistant mouse strain 1 (SAMR1) and SAMP8 mice were assigned to the following groups, with 15 animals in each group: SAMR1 control (Rc), SAMP8 control (Pc), SAMP8 acupuncture (Pa), SAMP8 sham-acupuncture (Psa). The Pa group was given acupuncture treatment once daily for 15 days. Neuromuscular coordination and cognitive function of the mice were evaluated by the tightrope test and Morris water maze test, respectively. The number of neurons in the CA1, CA3 and dentate gyrus (DG) regions of the hippocampus were measured. The levels of oxidative stress and protein carbonyl, mRNA and protein expression levels of Hsp84 and Hsp86 in the hippocampus were detected. Results: Compared with the Rc group, in the Pc mice there was a lower success rate for the tightrope test, impaired cognitive abilities, a decline in neuron numbers, reduced levels of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), increased levels of superoxide anion and protein carbonyl, and decreased mRNA and protein levels of Hsp84 and Hsp86 (all P<0.05). After acupuncture treatment, the success rate for the tightrope test was elevated, cognitive function was improved, neuron numbers were enhanced, levels of SOD and GSH-Px were increased, levels of superoxide anion and protein carbonyl were decreased, and Hsp84 and Hsp86 mRNA and protein expression were increased in the Pa mice when compared with the Pc and Psa groups (all P<0.05). Conclusion: Acupuncture may delay brain ageing in SAMP8 mice by reducing oxidative protein damage and promoting Hsp84 and Hsp86 expression.

Comparative Toxicity Studies at Reduced and Ambient Pressures I. Acute Response

AIHAJ ◽  
1965 ◽  
Vol 26 (6) ◽  
pp. 568-573 ◽  
Author(s):  
James M. McNerney ◽  
James D. MacEwen
Keyword(s):  
Toxicity Studies ◽  
Acute Response ◽  
Comparative Toxicity

Comparative toxicity studies in birds using nimesulide and diclofenac sodium

2006 ◽  
Vol 22 (2) ◽  
pp. 142-147 ◽  
Author(s):  
N.C. Prakash Reddy ◽  
Y. Anjaneyulu ◽  
B. Sivasankari ◽  
K. Ananda Rao
Keyword(s):  
Diclofenac Sodium ◽  
Toxicity Studies ◽  
Comparative Toxicity

Comparative Toxicity Studies on Ten Antibiotics in Current Use

1959 ◽  
Vol 11 (1) ◽  
pp. 737-741 ◽  
Author(s):  
A. L. Bacharach ◽  
Barbara. J. Clark ◽  
Marian. Mcculloch ◽  
E. G. Tomich
Keyword(s):  
Toxicity Studies ◽  
Comparative Toxicity

Comparative toxicity studies of NSAIDs in birds: A criticism of Reddy et al.

2007 ◽  
Vol 23 (2) ◽  
pp. 254-255 ◽  
Author(s):  
Richard Cuthbert ◽  
Deborah J. Pain ◽  
Rhys E. Green ◽  
Gerry Swan ◽  
Devendra Swarup
Keyword(s):  
Toxicity Studies ◽  
Comparative Toxicity
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