Synthesis and Crystal Structure of Binuclear Copper(II) Complex Bridged byN-(2-Hydroxyphenyl)-N′-[3-(diethylamino)propyl]oxamide: In Vitro Anticancer Activity and Reactivity Toward DNA and Protein

2013 ◽  
Vol 27 (8) ◽  
pp. 412-424 ◽  
Author(s):  
Yang Gao ◽  
Yan-Tuan Li ◽  
Zhi-Yong Wu ◽  
Cui-Wei Yan
Keyword(s):  
Crystal Structure ◽  
Anticancer Activity ◽  
Binuclear Copper ◽  
Synthesis And Crystal Structure

scholarly journals Synthesis and crystal structure of new monometallic Ni(ii) and Co(ii) complexes with an asymmetrical aroylhydrazone: effects of the complexes on DNA/protein binding property, molecular docking, and in vitro anticancer activity

RSC Advances ◽  
2017 ◽  
Vol 7 (78) ◽  
pp. 49404-49422 ◽  
Author(s):  
Yueqin Li ◽  
Zhiwei Yang ◽  
Minya Zhou ◽  
Yun Li
Keyword(s):  
Crystal Structure ◽  
Molecular Docking ◽  
Protein Binding ◽  
Anticancer Activity ◽  
Cobalt Complexes ◽  
Docking Studies ◽  
Binding Property ◽  
Synthesis And Crystal Structure ◽  
Molecular Docking Studies

Cytotoxic nickel and cobalt complexes containing asymmetrical aroylhydrazone were synthesized and their interactions with HS–DNA and BSA protein were investigated, which was supported by molecular docking studies.

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