Evaluation of the antimicrobial activity of ebselen: Role of the yeast plasma membrane H+-ATPase

2007 ◽  
Vol 21 (5) ◽  
pp. 252-264 ◽  
Author(s):  
Grace Chan ◽  
Diane Hardej ◽  
Michelle Santoro ◽  
Cesar Lau-Cam ◽  
Blase Billack
Keyword(s):  
Antimicrobial Activity ◽  
Plasma Membrane ◽  
Yeast Plasma Membrane

Conformational Changes of Yeast Plasma Membrane H+-ATPase during Activation by Glucose:  Role of Threonine-912 in the Carboxy-Terminal Tail†

Biochemistry ◽  
2005 ◽  
Vol 44 (50) ◽  
pp. 16624-16632 ◽  
Author(s):  
Silvia Lecchi ◽  
Kenneth E. Allen ◽  
Juan Pablo Pardo ◽  
A. Brett Mason ◽  
Carolyn W. Slayman
Keyword(s):  
Plasma Membrane ◽  
Conformational Changes ◽  
Yeast Plasma Membrane ◽  
Carboxy Terminal

scholarly journals Functional Role of Charged Residues in the Transmembrane Segments of the Yeast Plasma Membrane H+-ATPase

2000 ◽  
Vol 275 (21) ◽  
pp. 15709-15716 ◽  
Author(s):  
Valery V. Petrov ◽  
Kristine P. Padmanabha ◽  
Robert K. Nakamoto ◽  
Kenneth E. Allen ◽  
Carolyn W. Slayman
Keyword(s):  
Plasma Membrane ◽  
Functional Role ◽  
Yeast Plasma Membrane ◽  
Transmembrane Segments ◽  
Charged Residues

The role of two small proteolipids associated to the H+-ATPase from yeast plasma membrane

1994 ◽  
pp. 199-204
Author(s):  
Catherine Navarre ◽  
Serge Leterme ◽  
Michel Ghislain ◽  
André Goffeau
Keyword(s):  
Plasma Membrane ◽  
Yeast Plasma Membrane

Yeast plasma-membrane H+-ATPase: Role of cys-409 in interaction of the enzyme with NEM and FITC

1997 ◽  
Vol 42 (3) ◽  
pp. 249-250 ◽  
Author(s):  
V. V. Petrov ◽  
J. P. Pardo ◽  
C. W. Slayman
Keyword(s):  
Plasma Membrane ◽  
Yeast Plasma Membrane

Yeast plasma-membrane H+-ATPase: The role of cysteine residues

1996 ◽  
Vol 41 (1) ◽  
pp. 119-121 ◽  
Author(s):  
V. V. Petrov ◽  
J. P. Pardo ◽  
C. W. Slayman
Keyword(s):  
Plasma Membrane ◽  
Cysteine Residues ◽  
Yeast Plasma Membrane

scholarly journals The role of the yeast plasma membrane SPS nutrient sensor in the metabolic response to extracellular amino acids

2008 ◽  
Vol 42 (1) ◽  
pp. 215-228 ◽  
Author(s):  
Hanna Forsberg ◽  
C. Fredrik Gilstring ◽  
Arezou Zargari ◽  
Paula Martínez ◽  
Per O. Ljungdahl
Keyword(s):  
Amino Acids ◽  
Plasma Membrane ◽  
Metabolic Response ◽  
Yeast Plasma Membrane

scholarly journals Periprotein membrane lipidomics and the role of lipids in transporter function in yeast

2020 ◽  
Author(s):  
Joury S van ‘t Klooster ◽  
Tan-Yun Cheng ◽  
Hendrik R Sikkema ◽  
Aike Jeucken ◽  
D. Branch Moody ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Fatty Acids ◽  
Plasma Membrane ◽  
Unsaturated Fatty Acids ◽  
Protein Composition ◽  
Yeast Plasma Membrane ◽  
High Lipid ◽  
Lipid Particles ◽  
Solute Transporters

AbstractThe yeast plasma membrane is segregated into domains: the Micro-Compartment-of-Can1 (MCC) and Pma1 (MCP) have a different protein composition, but their lipid composition is largely unknown. We extracted proteins residing in these microdomains via stoichiometric capture of lipids and proteins in styrene-maleic-acid-lipid-particles (SMALPs). We purified SMALPs by affinity chromatography and quantitatively analyzed the lipids by mass spectrometry and their role in transporter function. We found that phospholipid and sterol concentrations are similar for MCC and MCP, but sphingolipids are enriched in MCP. Ergosterol is depleted from the periprotein lipidome, whereas phosphatidylserine is enriched relative to the bulk of the plasma membrane. Phosphatidylserine, non-bilayer lipids and ergosterol are essential for activity of Lyp1; the transporter also requires a balance of saturated/unsaturated fatty acids. We propose that proteins can function in the yeast plasma membrane by the disordered state of surrounded lipids and diffuse slowly in domains of high lipid order.Impact statementMembrane protein-specific lipidomics provides information on the organization of the yeast plasma membrane and the functioning of solute transporters

scholarly journals Role of transmembrane segment M8 in the biogenesis and function of yeast plasma-membrane H+-ATPase

2007 ◽  
Vol 1768 (10) ◽  
pp. 2383-2392 ◽  
Author(s):  
Guadalupe Guerra ◽  
Valery V. Petrov ◽  
Kenneth E. Allen ◽  
Manuel Miranda ◽  
Juan Pablo Pardo ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Transmembrane Segment ◽  
Yeast Plasma Membrane ◽  
And Function
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