Ronacaleret, a calcium-sensing receptor antagonist, increases trabecular but not cortical bone in postmenopausal women

2012 ◽  
Vol 27 (2) ◽  
pp. 255-262 ◽  
Author(s):  
Lorraine A Fitzpatrick ◽  
Christine E Dabrowski ◽  
Gregory Cicconetti ◽  
David N Gordon ◽  
Thomas Fuerst ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Cortical Bone ◽  
Postmenopausal Women ◽  
Calcium Sensing Receptor ◽  
Calcium Sensing

scholarly journals A Novel Calcium-Sensing Receptor Antagonist Transiently Stimulates Parathyroid Hormone Secretion in Vivo

Endocrinology ◽  
2005 ◽  
Vol 146 (4) ◽  
pp. 2015-2022 ◽  
Author(s):  
Brian J. Arey ◽  
Ramakrishna Seethala ◽  
Zhengping Ma ◽  
Aberra Fura ◽  
Jennifer Morin ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Receptor Antagonist ◽  
Hormone Secretion ◽  
Calcium Sensing Receptor ◽  
Calcium Sensing

An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation

Bone ◽  
2010 ◽  
Vol 46 (2) ◽  
pp. 534-542 ◽  
Author(s):  
Sanjay Kumar ◽  
Christopher J. Matheny ◽  
Sandra J. Hoffman ◽  
Robert W. Marquis ◽  
Maggie Schultz ◽  
...  
Keyword(s):  
Bone Formation ◽  
Receptor Antagonist ◽  
Plasma Concentrations ◽  
Calcium Sensing Receptor ◽  
Calcium Sensing ◽  
Active Calcium ◽  
Orally Active
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