scholarly journals Associations Between Lean Mass, Muscle Strength and Power, and Skeletal Size, Density and Strength in Older Men

2018 ◽  
Vol 33 (9) ◽  
pp. 1612-1621 ◽  
Author(s):  
Didier Chalhoub ◽  
Robert Boudreau ◽  
Susan Greenspan ◽  
Anne B Newman ◽  
Joseph Zmuda ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Lean Mass ◽  
Older Men ◽  
Skeletal Size

Associations of Impaired Renal Function With Declines in Muscle Strength and Muscle Function in Older Men: Findings From the CHAMP Study

2019 ◽  
Vol 74 (11) ◽  
pp. 1812-1820 ◽  
Author(s):  
Tadashi Toyama ◽  
Oliver van den Broek-Best ◽  
Toshiaki Ohkuma ◽  
David Handelsman ◽  
Louise M Waite ◽  
...  
Keyword(s):  
Renal Function ◽  
Muscle Strength ◽  
Renal Impairment ◽  
Grip Strength ◽  
Lean Mass ◽  
Gait Speed ◽  
Muscle Function ◽  
Older Men ◽  
Community Dwelling ◽  
Physical Parameters

Abstract Background Advanced kidney disease is associated with reduced muscle strength and physical performance. However, associations between early stages of renal impairment and physical outcomes are unclear. Methods The Concord Health and Ageing in Men Project is a prospective study of 1,705 community-dwelling men aged 70 years and older. Participants with estimated glomerular filtration rate (eGFR) more than 30 mL/min/1.73 m2 were included and further divided into four eGFR categories. Physical parameters including grip strength, gait speed, appendicular lean mass (ALM, a sum of skeletal mass of arms and legs), ALM adjusted for body mass index (ALMBMI), and muscle function (measured using grip strength divided by arm lean mass) were assessed at both baseline and 5-year follow-up. Associations between kidney function and changes in physical parameters were analyzed using linear and logistic regression models. Results Our study included 789 men with a median age of 75 years and median eGFR of 72 mL/min/1.73 m2 at baseline. Over 5 years, grip strength, gait speed, ALMBMI, and muscle function all declined in the whole cohort, compared with baseline. The multivariable analyses showed that poorer renal function was associated with more rapid declines in grip strength, gait speed, and muscle function in participants with mild-to-moderate renal impairment (GFR category stage G3, eGFR < 60 mL/min/1.73 m2) (p = .01, p < .01, p = .02, respectively) but less so in those with eGFR more than 60 mL/min/1.73 m2, whereas eGFR category did not have a significant impact on declines in ALMBMI. These results remained unchanged with or without adjustment for age. Conclusions In community-dwelling older men, mild-to-moderate renal impairment at baseline was associated with declines in grip strength, gait speed, and muscle function over time despite preservation of muscle mass.

scholarly journals Muscle strength and gait speed rather than lean mass are better indicators for poor cognitive function in older men

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Sophia X. Sui ◽  
Kara L. Holloway-Kew ◽  
Natalie K. Hyde ◽  
Lana J. Williams ◽  
Sarah Leach ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Muscle Strength ◽  
Lean Mass ◽  
Gait Speed ◽  
Older Men ◽  
Poor Cognitive Function

scholarly journals Lean Mass, Muscle Strength and Gene Expression in Community Dwelling Older Men: Findings from the Hertfordshire Sarcopenia Study (HSS)

2014 ◽  
Vol 95 (4) ◽  
pp. 308-316 ◽  
Author(s):  
Harnish P. Patel ◽  
Nasser Al-Shanti ◽  
Lucy C. Davies ◽  
Sheila J. Barton ◽  
Miranda D. Grounds ◽  
...  
Keyword(s):  
Gene Expression ◽  
Muscle Strength ◽  
Lean Mass ◽  
Older Men ◽  
Community Dwelling

scholarly journals 103 * LEAN MASS, MUSCLE STRENGTH AND GENE EXPRESSION IN COMMUNITY DWELLING OLDER MEN

2014 ◽  
Vol 43 (suppl 1) ◽  
pp. i28-i28
Author(s):  
H. P. Patel ◽  
N. Al-Shanti ◽  
L. C. Davies ◽  
S. J. Barton ◽  
M. D. Grounds ◽  
...  
Keyword(s):  
Gene Expression ◽  
Muscle Strength ◽  
Lean Mass ◽  
Older Men ◽  
Community Dwelling

scholarly journals COVID-19 era in long-term cardiac rehabilitation programs: how was muscle strenght and lean mass affected in cardiovascular patients?

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
M Borges ◽  
M Lemos Pires ◽  
R Pinto ◽  
G De Sa ◽  
I Ricardo ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Cardiac Rehabilitation ◽  
Lean Mass ◽  
Lower Limb ◽  
Lower Limbs ◽  
Phase Iii ◽  
Face To Face ◽  
Home Based ◽  
Lower Limb Strength

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Exercise prescription is one of the main components of phase III Cardiac Rehabilitation (CR) programs due to its documented prognostic benefits. It has been well established that, when added to aerobic training, resistance training (RT) leads to greater improvements in peripheral muscle strength and muscle mass in patients with cardiovascular disease (CVD). With COVID-19, most centre-based CR programs had to be suspended and CR patients had to readjust their RT program to a home-based model where weight training was more difficult to perform. How COVID-19 Era impacted lean mass and muscle strength in trained CVD patients who were attending long-term CR programs has yet to be discussed. Purpose To assess upper and lower limb muscle strength and lean mass in CVD patients who had their centre-based CR program suspended due to COVID-19 and compare it with previous assessments. Methods 87 CVD patients (mean age 62.9 ± 9.1, 82.8% male), before COVID-19, were attending a phase III centre-based CR program 3x/week and were evaluated annually. After 7 months of suspension, 57.5% (n = 50) patients returned to the face-to-face CR program. Despite all constraints caused by COVID-19, body composition and muscle strength of 35 participants (mean age 64.7 ± 7.9, 88.6% male) were assessed. We compared this assessment with previous years and established three assessment time points: M1) one year before COVID-19 (2018); M2) last assessment before COVID-19 (2019); M3) the assessment 7 months after CR program suspension (last trimester of 2020). Upper limbs strength was measured using a JAMAR dynamometer, 30 second chair stand test (number of repetitions – reps) was used to measure lower limbs strength and dual energy x-ray absorptiometry was used to measure upper and lower limbs lean mass. Repeated measures ANOVA were used. Results Intention to treat analysis showed that upper and lower limbs lean mass did not change from M1 to M2 but decreased significantly from M2 to M3 (arms lean mass in M2: 5.68 ± 1.00kg vs M3: 5.52 ± 1.06kg, p = 0.004; legs lean mass in M2: 17.40 ± 2.46kg vs M3: 16.77 ± 2.61kg, p = 0.040). Lower limb strength also decreased significantly from M2 to M3 (M2: 23.31 ± 5.76 reps vs M3: 21.11 ± 5.31 reps, p = 0.014) after remaining stable in the year prior to COVID-19. Upper limb strength improved significantly from M1 to M2 (M1: 39.00 ± 8.64kg vs M2: 40.53 ± 8.77kg, p = 0.034) but did not change significantly from M2 to M3 (M2 vs M3: 41.29 ± 9.13kg, p = 0.517). Conclusion After CR centre-based suspension due to COVID-19, we observed a decrease in upper and lower limbs lean mass and lower limb strength in previously trained CVD patients. These results should emphasize the need to promote all efforts to maintain physical activity and RT through alternative effective home-based CR programs when face-to-face models are not available or possible to be implemented.

scholarly journals Type 2 Diabetes Reduces the Muscle Anabolic Effect of Resistance Exercise Training in Older Adults

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 529-529
Author(s):  
Amanda Randolph ◽  
Tatiana Moro ◽  
Adetutu Odejimi ◽  
Blake Rasmussen ◽  
Elena Volpi
Keyword(s):  
Type 2 Diabetes ◽  
Older Adults ◽  
Muscle Strength ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Lean Mass ◽  
Synthesis Rate ◽  
Resistance Exercise Training ◽  
Appendicular Lean Mass

Abstract Type 2 Diabetes Mellitus (T2DM) accelerates the incidence and increases the prevalence of sarcopenia in older adults. This suggests an urgent need for identifying effective sarcopenia treatments for older adults with T2DM. It is unknown whether traditional approaches, such as progressive resistance exercise training (PRET), can effectively counteract sarcopenia in older patients with T2DM. To test the efficacy of PRET for the treatment of sarcopenia in older adults with T2DM, 30 subjects (15 T2DM and 15 age- and sex- matched controls) underwent metabolic testing with muscle biopsies before and after a 13-week full-body PRET program. Primary outcome measures included changes in appendicular lean mass, muscle strength, and mixed muscle fractional synthesis rate (FSR). Before PRET, BMI-adjusted appendicular lean mass was significantly lower in the T2DM group (0.7095±0.0381 versus 0.8151±0.0439, p&lt;0.0001). As a result of PRET, appendicular lean mass adjusted for BMI and muscle strength increased significantly in both groups, but to a lesser extent for the T2DM group (p=0.0009) . Preliminary results for FSR (n=25) indicate that subjects with T2DM had lower basal FSR prior to PRET (p=0.0197) . Basal FSR increased significantly in the control group after PRET (p=0.0196), while it did not change in the T2DM group (p=0.3537). These results suggest that in older adults the positive effect of PRET on muscle anabolism and strength is reduced by T2DM . Thus, older adults with T2DM may require more intensive, multimodal and targeted sarcopenia treatment. Funded by NIH R01AG049611 and P30AG024832.

scholarly journals Insulin Sensitizers May Attenuate Lean Mass Loss in Older Men With Diabetes

Diabetes Care ◽  
2011 ◽  
Vol 34 (11) ◽  
pp. 2381-2386 ◽  
Author(s):  
Christine G. Lee ◽  
Edward J. Boyko ◽  
Elizabeth Barrett-Connor ◽  
Iva Miljkovic ◽  
Andrew R. Hoffman ◽  
...  
Keyword(s):  
Mass Loss ◽  
Lean Mass ◽  
Older Men ◽  
Insulin Sensitizers

scholarly journals Individual and joint trajectories of change in bone, lean mass and physical performance in older men

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Peggy M. Cawthon ◽  
Neeta Parimi ◽  
Lisa Langsetmo ◽  
Jane A. Cauley ◽  
Kristine E. Ensrud ◽  
...  
Keyword(s):  
Physical Performance ◽  
Lean Mass ◽  
Older Men ◽  
Trajectories Of Change

scholarly journals The effect of resistance training, detraining and retraining on muscle strength and power, myofibre size, satellite cells and myonuclei in older men

2020 ◽  
Vol 133 ◽  
pp. 110860 ◽  
Author(s):  
Sara Blocquiaux ◽  
Tatiane Gorski ◽  
Evelien Van Roie ◽  
Monique Ramaekers ◽  
Ruud Van Thienen ◽  
...  
Keyword(s):  
Resistance Training ◽  
Muscle Strength ◽  
Satellite Cells ◽  
Older Men
Sign in / Sign up

Export Citation Format

Share Document