scholarly journals Evaluation of the Treatment Strategies for Medication-Related Osteonecrosis of the Jaws (MRONJ) and the Factors Affecting Treatment Outcome: A Multicenter Retrospective Study with Propensity Score Matching Analysis

2017 ◽  
Vol 32 (10) ◽  
pp. 2022-2029 ◽  
Author(s):  
Saki Hayashida ◽  
Sakiko Soutome ◽  
Souichi Yanamoto ◽  
Shigeyuki Fujita ◽  
Takumi Hasegawa ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Retrospective Study ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Treatment Strategies ◽  
Factors Affecting ◽  
Propensity Score Matching Analysis ◽  
Osteonecrosis Of The Jaws

scholarly journals Comparison of the Treatment Outcome Between Primary Intratympanic Steroid and Salvage Intratympanic Steroid Protocol in Sudden Sensorineural Hearing Loss: Propensity Score Matching Analysis

2020 ◽  
Vol 63 (6) ◽  
pp. 252-258 ◽  
Author(s):  
Hee Won Seo ◽  
Ha Na Lee ◽  
Hyun Woong Jun ◽  
Hayoung Byun ◽  
Jae Ho Chung ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Treatment Outcome ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Sudden Sensorineural Hearing Loss ◽  
Control Group ◽  
Systemic Steroid ◽  
Hearing Level ◽  
Propensity Score Matching Analysis ◽  
And Control

Background and Objectives We aimed to compare the treatment outcomes of primary intratympanic steroid (ITS) and the salvage ITS protocol.Subjects and Method We assessed 440 patients with unilateral idiopathic sudden sensorineural hearing loss (ISSNHL) from January 2016 to December 2019. Of the 440 patients, 37 patients received ITS only as a primary treatment while other patients received systemic steroid; of those remaining patients, 276 received systemic steroid as well as ITS as a salvage treatment. We performed a 1:2 propensity score matching analysis for both groups using parameters such as the initial hearing level, presence of vertigo, onset of treatment, age, sex, hypertension and diabetes. The rate of hearing recovery was determinied by comparing the matching propensity score between the primary ITS and the control group according to the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) guideline and Siegel’s criteria.Results Of the 440 ISSNHL patients, 28.9% received systemic steroid only and 62.6% of patients were managed with systemic steroid plus salvage ITS. Thirty-seven patients (8.4%) were managed with ITS only. While 36.8% of patients completely recovered, 35.0% did not recover their hearing according to AAO-HNS guideline. The propensity score matching showed that the initial hearing level, age and onset of treatment were not significantly different between the primary ITS and control group. Regarding the treatment outcome, complete recovery rate for the primary ITS group and control group were 29.7% and 33.8%, respectively. Although the recovery rate of the salvage ITS protocol group was higher than that of the primary ITS group, statistical significance was not identified.Conclusion Treatment strategies of primary ITS and salvage ITS protocol did not significantly affect the clinical outcomes of ISSNHL differently.

The effect of scissor-type versus non-scissor-type knives on the technical outcomes in endoscopic submucosal dissection for superficial esophageal cancer: a multi-center retrospective study

2019 ◽  
Vol 33 (4) ◽  
Author(s):  
Mitsuru Esaki ◽  
Yasuyo Hayashi ◽  
Hisatomo Ikehara ◽  
Eikichi Ihara ◽  
Toshiki Horii ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Retrospective Study ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Complete Resection ◽  
Procedure Time ◽  
Superficial Esophageal Cancer ◽  
En Bloc ◽  
Delayed Bleeding ◽  
Propensity Score Matching Analysis

SUMMARY The Clutch Cutter was invented as a scissor-type knife for endoscopic submucosal dissection (ESD) of gastrointestinal neoplasms. ESD with the scissor-type knife (ESD-S) may be considered a technically easier procedure than ESD with non-scissor-type knives (ESD-NS). Therefore, this study aimed to compare the technical outcomes of ESD-S with those of ESD-NS for superficial esophageal cancer. This was a multicenter retrospective study. Patients with superficial esophageal cancer treated with ESD between October 2015 and March 2018 at three hospitals were retrospectively reviewed. The ESD-S group had 48 patients and the ESD-NS group had 114 patients. A propensity score matching analysis was performed to compensate for the confounding bias between both groups. Multivariate analyses and propensity score matching were used to adjust for age, sex, the tumor size, tumor location, tumor depth, degree of tumor circumference, operator level, usage of the traction method, and the sedation method. The primary outcome was the procedure time of the ESD. Secondary outcomes were the rate of en-bloc/complete resection and the rate of complications including perforation, delayed bleeding, and stricture. Propensity score matching analysis provided 36 matched pairs. Median procedure time in the ESD-S group was significantly shorter than that in the ESD-NS group (44.0 min vs. 66.5 min, P = 0.020). In addition, the treatment outcomes were similar in both groups (en-bloc resection: 100% vs. 97.2%, P = 1; complete resection: 88.9% vs. 86.1%, P = 1; curative resection: 80.6% vs. 77.8%, P = 1; perforation: 0% vs. 5.6%, P = 0.49; delayed bleeding: 0% in both groups; stricture: 2.8% vs. 8.3%, P = 0.61). ESD-S was associated with a shorter procedure time than ESD-NS, without an increase in the incidence of complications. Therefore, the scissor-type knife should be considered as an endo-knife for ESD of superficial esophageal cancers.

scholarly journals Previous Stenting Doesn’t Affect Outcome of Extensive Endarterectomy for Diffuse Coronary Artery Total Occlusions: A Propensity Score Matching Analysis

2021 ◽  
Vol 24 (2) ◽  
pp. E243-E248
Author(s):  
Hamdy Singab ◽  
Gamal Sami
Keyword(s):  
Retrospective Study ◽  
Coronary Artery ◽  
Postoperative Complications ◽  
Propensity Score ◽  
Survival Time ◽  
Propensity Score Matching ◽  
Graft Patency ◽  
Primary Study ◽  
Outcome Parameters ◽  
Propensity Score Matching Analysis

Background and aim: Extensive diffuse coronary artery total occlusions (CTOs) constitute a challenging surgical problem. Extensive coronary endarterectomy (CE) combined with CABG was suggested as a revascularization technique. It was claimed that previous stenting may affect outcome. The present study aimed to report the outcome of LAD endarterectomy for CTO and to determine the effect of previous stenting on this outcome. Patients and methods: The present retrospective study was conducted on 194 patients with CTO indicated for left anterior descending artery (LAD) endarterectomy. To reduce the bias related to unbalanced patients selection, propensity score matching analysis was used. According to the propensity score, 194 patients were included in the analysis. They comprised 66 patients with previous stent and 128 patients without previous stent. Patients were followed for a median (range) of 74.0 (6.0-149.0) months. The primary study outcome was LAD graft patency. Other outcome parameters included postoperative complications, hospital and ICU stay, and mortality. Results: Comparison between the studied groups regarding outcome parameters revealed no significant differences regarding graft patency (93.9% versus 89.1%; P = .27), graft survival (median [95% CI]: 134.3 months [127.0-141.5] versus 135.2 months [128.4-142.0]; P = .35), patients’ survival (93.9% versus 91.4%) and patients’ survival time (median [95% CI]: 132.3 months [125.0-139.5] versus 138.0 months [132.0-144.1]; P = .75]. Conclusion: The present study supports using CE as an adjuvant technique with CABG in patients with TCOs.   Patients and methods: The present retrospective study was conducted on 194 patients with CTO indicated for left anterior descending artery (LAD) endarterectomy. To reduce the bias related to unbalanced patients selection, propensity score matching analysis was used. According to the propensity score, 194 patients were included in the analysis. They comprised 66 patients with previous stent and 128 patients without previous stent. Patients were followed for a median (range) of 74.0 (6.0-149.0) months. The primary study outcome was LAD graft patency. Other outcome parameters included postoperative complications, hospital and ICU stay and mortality.   Results: Comparison between the studied groups regarding outcome parameters revealed no significant differences regarding graft patency (93.9 % versus 89.1; p=0.27), graft survival [median (95% CI): 134.3 months (127.0-141.5) versus 135.2 months (128.4-142.0); p=0.35], patients’ survival (93.9 % versus 91.4 %) and patients’ survival time [median (95% CI): (132.3 months (125.0-139.5) versus 138.0 months (132.0-144.1); p= 0.75].   Conclusions: The present study supports use CE as an adjuvant technique with CABG in patients with TCOs.

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