scholarly journals Microindentation for in vivo measurement of bone tissue material properties in atypical femoral fracture patients and controls

2012 ◽  
Vol 28 (1) ◽  
pp. 162-168 ◽  
Author(s):  
Roberto C Güerri-Fernández ◽  
Xavier Nogués ◽  
José M Quesada Gómez ◽  
Elisa Torres del Pliego ◽  
Lluís Puig ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Material Properties ◽  
Femoral Fracture ◽  
Atypical Femoral Fracture ◽  
In Vivo Measurement ◽  
Tissue Material

scholarly journals Retrospective Evaluation and Framework Development of Bone Anisotropic Material Behavior Compared with Elastic, Elastic-Plastic, and Hyper-Elastic Properties

2021 ◽  
Vol 9 (1) ◽  
pp. 9
Author(s):  
Farah Hamandi ◽  
James T. Tsatalis ◽  
Tarun Goswami
Keyword(s):  
Bone Tissue ◽  
Material Properties ◽  
Anisotropic Material ◽  
Material Behavior ◽  
Imaging Data ◽  
Premature Failure ◽  
Elastic Plastic ◽  
Significant Difference ◽  
Hyper Elastic

The main motivation for studying damage in bone tissue is to better understand how damage develops in the bone tissue and how it progresses. Such knowledge may help in the surgical aspects of joint replacement, fracture fixation or establishing the fracture tolerance of bones to prevent injury. Currently, there are no standards that create a realistic bone model with anisotropic material properties, although several protocols have been suggested. This study seeks to retrospectively evaluate the damage of bone tissue with respect to patient demography including age, gender, race, body mass index (BMI), height, and weight, and their role in causing fracture. Investigators believe that properties derived from CT imaging data to estimate the material properties of bone tissue provides more realistic models. Quantifying and associating damage with in vivo conditions will provide the required information to develop mathematical equations and procedures to predict the premature failure and potentially mitigate problems before they begin. Creating a realistic model for bone tissue can predict the premature failure(s), provide preliminary results before getting the surgery, and optimize the design of orthopaedic implants. A comparison was performed between the proposed model and previous efforts, where they used elastic, hyper- elastic, or elastic-plastic properties. Results showed that there was a significant difference between the anisotropic material properties of bone when compared with unrealistic previous methods. The results showed that the density is 50% higher in male subjects than female subjects. Additionally, the results showed that the density is 47.91% higher in Black subjects than Mixed subjects, 53.27% higher than Caucasian subjects and 57.41% higher than Asian. In general, race should be considered during modeling implants or suggesting therapeutic techniques.

Long-term exposure to hypobaric hypoxia in rat affects femur cross-sectional geometry and bone tissue material properties

2009 ◽  
Vol 191 (2) ◽  
pp. 212-217 ◽  
Author(s):  
Clarisa Bozzini ◽  
María I. Olivera ◽  
Patricia Huygens ◽  
Rosa M. Alippi ◽  
Carlos E. Bozzini
Keyword(s):  
Bone Tissue ◽  
Material Properties ◽  
Hypobaric Hypoxia ◽  
Cross Sectional ◽  
Tissue Material

In Vivo Measurement of the Mechanical Properties of Bone Tissue. Preliminary Results

1983 ◽  
Vol 12 (1) ◽  
pp. 43-45 ◽  
Author(s):  
F Burny ◽  
O Saric ◽  
R Bourgois ◽  
M Donkerwolcke ◽  
Y Andrianne
Keyword(s):  
Mechanical Properties ◽  
Bone Tissue ◽  
Preliminary Report ◽  
Mechanical Characteristics ◽  
Maximum Torque ◽  
Preliminary Results ◽  
In Vivo Measurement

The paper is a preliminary report on the possibility of measuring the mechanical characteristics of the bone at the time of the anchorage of the osteosynthesis. The measurement of the maximum torque of a screw could be representative for the strength of the material.

scholarly journals Probing tissue-scale deformation by in vivo force application reveals a fast tissue softening during early embryogenesis

2017 ◽  
Author(s):  
Arturo D’Angelo ◽  
Kai Dierkes ◽  
Carlo Carolis ◽  
Guillaume Salbreux ◽  
Jérôme Solon
Keyword(s):  
Material Properties ◽  
Rapid Change ◽  
Early Embryogenesis ◽  
Tissue Response ◽  
Mechanical Parameters ◽  
Major Contributor ◽  
Pharmacological Treatments ◽  
Tissue Material ◽  
Over Time

AbstractDuring development, cell-generated forces induce tissue-scale deformations to shape the organism. Here, we present a method that allows to quantitatively relate such tissue-scale deformations to spatially localized forces and measure mechanical properties of epithelia in vivo. Our approach is based on the application of controlled forces on microparticles embedded in individual cells of an embryo. Combining measurements of the bead displacement with the analysis of induced deformation fields in a continuum mechanics framework, we can quantify tissue material properties and follow their change over time. In particular, we uncover a rapid change in tissue response occurring during Drosophila cellularization, resulting from a softening of the blastoderm and an increase of external friction. Pharmacological treatments reveal that in addition to actomyosin, the microtubule cytoskeleton is a major contributor to epithelial mechanics at that stage. Overall, our method allows for measuring essential mechanical parameters governing tissue-scale deformations and flows occurring during morphogenesis.

Structural Properties of Immature Canine Bone

1981 ◽  
Vol 103 (4) ◽  
pp. 232-238 ◽  
Author(s):  
P. A. Torzilli ◽  
K. Takebe ◽  
A. H. Burstein ◽  
K. G. Heiple
Keyword(s):  
Bone Tissue ◽  
Structural Properties ◽  
Material Properties ◽  
Growth Process ◽  
Bending Strength ◽  
Developmental Process ◽  
Long Bones ◽  
Bending Tests ◽  
Four Point Bending ◽  
Tissue Material

Structural properties of growing canine long bones were determined from three and four-point bending tests. Mechanical and geometric properties were found to follow a biphasic growth process, with a rapid increase in bending strength and moment of inertia from 1 to 24 wk of age and a substantially decreased rate thereafter to maturity. Predicted bone tissue material properties were also found to follow this biphasic developmental process.

MICRO-FINITE ELEMENT ANALYSIS OF TRABECULAR BONE YIELD BEHAVIOR — EFFECTS OF TISSUE NONLINEAR MATERIAL PROPERTIES

2011 ◽  
Vol 11 (03) ◽  
pp. 563-580 ◽  
Author(s):  
HE GONG ◽  
MING ZHANG ◽  
YUBO FAN
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Trabecular Bone ◽  
Bone Tissue ◽  
Material Properties ◽  
Material Nonlinearity ◽  
Nonlinear Material ◽  
Yield Strain ◽  
Element Analysis ◽  
Tissue Material

Bone tissue material nonlinearity and large deformations within the trabecular network are important for the characterization of failure behavior of trabecular bone at both the apparent and tissue levels. Micro-finite element analysis (μFEA) is a useful tool for determining the mechanical properties of trabecular bone due to certain experimental difficulties. The aim of this study was to determine the effects of bone tissue nonlinear material properties on the apparent- and tissue-level mechanical parameters of trabecular bone using μFEA. A bilinear tissue constitutive model was proposed to describe the bone tissue material nonlinearity. Two trabecular specimens with different micro-architectures were taken as examples. The effects of four parameters, i.e., tissue Young's modulus, tissue yield strain in tension, tissue yield strain in compression, and post-yield modulus on the apparent yield stress/strain, tissue von Mises stress distribution, the amount of tissue elements yielded in compression and tension under compressive and tensile loading conditions were obtained using nine cases for different values of those parameters by totally 36 nonlinear μFEA. These data may provide a reference for more sophisticated evaluations of bone strength and the related fracture risk.

In vivo measurement of the mechanical properties of bone tissue

1980 ◽  
Vol 13 (9) ◽  
pp. 796
Author(s):  
F. Burny ◽  
R. Bourgois ◽  
M. Donkerwolcke ◽  
O. Saric ◽  
J. Jedwab
Keyword(s):  
Mechanical Properties ◽  
Bone Tissue ◽  
In Vivo Measurement

scholarly journals Microindentation for in vivo measurement of bone tissue mechanical properties in humans

2010 ◽  
Vol 25 (8) ◽  
pp. 1877-1885 ◽  
Author(s):  
Adolfo Diez-Perez ◽  
Roberto Güerri ◽  
Xavier Nogues ◽  
Enric Cáceres ◽  
Maria Jesus Peña ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Tissue ◽  
In Vivo Measurement
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