scholarly journals Osteoblast maturation and new bone formation in response to titanium implant surface features are reduced with age

2012 ◽  
Vol 27 (8) ◽  
pp. 1773-1783 ◽  
Author(s):  
Rene Olivares-Navarrete ◽  
Andrew L Raines ◽  
Sharon L Hyzy ◽  
Jung Hwa Park ◽  
Daphne L Hutton ◽  
...  
Keyword(s):  
Bone Formation ◽  
Titanium Implant ◽  
New Bone Formation ◽  
Implant Surface ◽  
Surface Features ◽  
Osteoblast Maturation ◽  
Titanium Implant Surface

scholarly journals Osseointegration of Maxillary Dental Implants in Diabetes Mellitus Patients: A Randomized Clinical Trial Human Histomorphometric Study

2020 ◽  
Vol 10 (19) ◽  
pp. 6762
Author(s):  
Lyly Sam ◽  
Siriporn Chattipakorn ◽  
Pathawee Khongkhunthian
Keyword(s):  
Type 2 Diabetes ◽  
Bone Formation ◽  
Dental Implants ◽  
Pearson Correlation ◽  
Titanium Implant ◽  
Control Group ◽  
Healthy Controls ◽  
New Bone Formation ◽  
Implant Surface

Background: Survival of dental implants in well-controlled Type 2 diabetes (T2DM) was found to be comparable to that in healthy patients. However, to our best knowledge, there have been no studies of the bone histomorphometry of osseointegration in patients with Type 2 diabetes. Purpose: To compare bone-implant-contact (BIC) and new bone formation between well-controlled Type 2 diabetes with HbA1c of less than 8% and healthy controls. Methods: 10 diabetic (T2DM) patients and 10 healthy controls were selected. Each patient received a 2.5 mm × 5 mm micro-implant in the maxilla, in either the premolar or first molar area. After 8 weeks of healing, the micro-implant was retrieved using a trephine bur and sent for bone histomorphometric analysis. A commercial titanium implant was immediately placed as the conventional treatment. Results: The mean BIC (30.73%) in T2DM patients was significantly lower than in the healthy patients (41.75%) (p = 0.01). New bone formation around the implant surface was reduced in T2DM patients (36.25%) compared to that in the control group (44.14%) (p = 0.028). The Pearson correlation coefficient revealed a strong correlation between increased HbA1c and decreased BIC (p < 0.05) and decreased new bone formation (p < 0.05). Conclusions: Within the limitation of this study, bone-to-implant contact and bone healing around dental implants in T2DM patients were significantly lower than in healthy patients.

Alkali-Modified Titanium Surface Stimulating Formation of Bone-Implant Interface

2007 ◽  
Vol 361-363 ◽  
pp. 749-752
Author(s):  
J. Strnad ◽  
Jan Macháček ◽  
Z. Strnad ◽  
C. Povýšil ◽  
Marie Strnadová
Keyword(s):  
Titanium Implant ◽  
Surface Characteristics ◽  
Healing Time ◽  
Machined Surface ◽  
Implant Surface ◽  
Bone Implant ◽  
Bone Response ◽  
Modified Surface ◽  
The Difference ◽  
Titanium Implant Surface

This study was carried out to assess the bone response to alkali-modified titanium implant surface (Bio surface), using histomorphometric investigation on an animal model. The mean net contribution of the Bio surface to the increase in bone implant contact (BIC) with reference to the turned, machined surface was evaluated at 7.94 % (BIC/week), within the first five weeks of healing. The contribution was expressed as the difference in the osseointegration rates ( BIC/'healing time) between the implants with alkali modified surface (Bio surface) and those with turned, machined surface. The surface characteristics that differed between the implant surfaces, i.e. surface morphology, specific surface area, contact angle, hydroxylation/hydration, may represent factors that influence the rate of osseointegration.

scholarly journals Erratum to: Biomechanical and histological evaluation of four different titanium implant surface modifications: an experimental study in the rabbit tibia

2015 ◽  
Vol 19 (7) ◽  
pp. 1699-1699 ◽  
Author(s):  
José Luis Calvo-Guirado ◽  
Marta Satorres ◽  
Bruno Negri ◽  
Piedad Ramirez-Fernandez ◽  
Jose Eduardo Maté-Sánchez de Val ◽  
...  
Keyword(s):  
Experimental Study ◽  
Titanium Implant ◽  
Surface Modifications ◽  
Histological Evaluation ◽  
Implant Surface ◽  
Rabbit Tibia ◽  
Titanium Implant Surface

State of Osseointegrated Titanium Implant Surfaces in Topographical Aspect

2018 ◽  
Vol 18 (12) ◽  
pp. 8016-8028 ◽  
Author(s):  
Xingying Qi† ◽  
Yuli Shang ◽  
Lei Sui
Keyword(s):  
Titanium Implant ◽  
World Market ◽  
Implant Surface ◽  
Preparation Methods ◽  
Clinical Investigations ◽  
Modify Surface ◽  
Metallic Biomaterial ◽  
Review State ◽  
Titanium Implant Surface ◽  
Selection Of

Titanium is a primary metallic biomaterial widely used in dental implants because of its favorable mechanical properties and osseointegration capability. Currently, increasing interests have been taken in the interaction between titanium implant surface and surrounding bone tissue, particularly in surface topographical aspect. There are currently several techniques developed to modify surface topographies in the world market of dental implant. In this review, state of titanium implant surfaces in topographical aspect is presented from relatively smooth surfaces to rougher ones with microtopographies and/or nanotopographies. Each surface is summarized with basic elaborations, preparation methods, mechanisms for cellular responses and current availabilities. It has been demonstrated that rough surfaces evolving from micro- to nano-scale, especially hierarchical micro-and nanotopographies, are favorable for faster and stronger osseointegration. Further experimental and clinical investigations will aid in the optimization of surface topography and clinical selection of suitable implants.

scholarly journals New titanium implant surface – An in vitro and in vivo evaluation

2019 ◽  
Vol 30 (S19) ◽  
pp. 213-213
Author(s):  
Sergio Gehrke ◽  
Leticia Pèrez‐DÌaz ◽  
Patricia Mazon ◽  
Piedad N. de Aza
Keyword(s):  
Titanium Implant ◽  
Implant Surface ◽  
In Vivo Evaluation ◽  
Titanium Implant Surface
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