scholarly journals Compromised trabecular microarchitecture and lower finite element estimates of radius and tibia bone strength in adults with turner syndrome: A cross-sectional study using high-resolution-pQCT

2012 ◽  
Vol 27 (8) ◽  
pp. 1794-1803 ◽  
Author(s):  
Stinus Hansen ◽  
Kim Brixen ◽  
Claus H Gravholt
Keyword(s):  
Finite Element ◽  
High Resolution ◽  
Turner Syndrome ◽  
Bone Strength ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Trabecular Microarchitecture ◽  
Cross Sectional ◽  
Tibia Bone

scholarly journals No QTc Prolongation in Girls and Women with Turner Syndrome

2020 ◽  
Vol 105 (11) ◽  
Author(s):  
Iris D Noordman ◽  
Anthonie L Duijnhouwer ◽  
Misty Coert ◽  
Melanie Bos ◽  
Marlies Kempers ◽  
...  
Keyword(s):  
Turner Syndrome ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Qtc Interval ◽  
Healthy Individuals ◽  
Sectional Study ◽  
Qtc Prolongation ◽  
Genetic Condition ◽  
Cross Sectional ◽  
Qt Intervals

Abstract Context Turner syndrome (TS) is a genetic condition that is reported to be associated with a prolonged rate-corrected QT (QTc) interval. Objectives To evaluate the prevalence of QTc prolongation in patients with TS, to compare their QTc intervals with healthy controls, and to investigate whether QTc prolongation is associated with a monosomy 45,X karyotype. Method Girls (n = 101) and women (n = 251) with TS visiting our center from 2004–2018 were included in this cross-sectional study. QT intervals of 12-leaded electrocardiograms were measured manually, using Bazett’s and Hodges formulas to correct for heart rate. A QTc interval of >450 ms for girls and >460 ms for women was considered prolonged. Corrected QT (QTc) intervals of patients with TS were compared to the QTc intervals of healthy girls and women from the same age groups derived from the literature. Results In total, 5% of the population with TS had a prolonged QTc interval using Bazett’s formula and 0% using Hodges formula. Mean QTc intervals of these patients were not prolonged compared with the QTc interval of healthy individuals from the literature. Girls showed shorter mean QTc intervals compared with women. We found no association between monosomy 45,X and prolongation of the QTc interval. Conclusions This study shows that the QTc interval in girls and women with TS is not prolonged compared with the general population derived from the literature, using both Bazett’s and Hodges formulas. Furthermore, girls show shorter QTc intervals compared with women, and a monosomy 45,X karyotype is not associated with QTc prolongation.

Dermatologic findings in individuals with Turner syndrome: a cross-sectional study across the lifespan

2021 ◽  
Author(s):  
Jordan Taylor Said ◽  
Deeti J. Pithadia ◽  
Emma Snyder ◽  
Ibrahim Elsharkawi ◽  
Angela Lin ◽  
...  
Keyword(s):  
Turner Syndrome ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Evaluation of constipation in children using high-resolution anorectal manometry

2021 ◽  
pp. 004947552110303
Author(s):  
Vishrutha S Poojari ◽  
Sonal Mirani ◽  
Naman S Shetty ◽  
Ira Shah
Keyword(s):  
High Resolution ◽  
Anal Sphincter ◽  
Faecal Incontinence ◽  
Anorectal Manometry ◽  
Hirschsprung's Disease ◽  
Functional Constipation ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Inhibitory Reflex

This prospective, cross-sectional study, conducted from July 2018 to March 2019, aimed to determine the causes of constipation using high-resolution anorectal manometry. Among 33 children enrolled in the study, 31 (94%) children presented with complaints of constipation with mean duration of 2.3 ± 2.5 years and 12 (36.4%) children also had associated complaints of faecal incontinence with mean duration of 3.5 ± 2.8 years. Seven children (21.2%) had normal high-resolution anorectal manometry parameters; anal sphincter hypotonia with decreased squeeze in one child, anal sphincter hypertonia with other abnormal parameters were noted in 25 and absent recto-anal inhibitory reflex in two. The causes of constipation determined were functional constipation in 30 (91%) children, suspected Hirschsprung’s disease in two and suspected dyssynergic defecatory disorder in one. Almost 90% had functional constipation of which anal hypotension and anal hypertension may be a part of chronic functional constipation.

Sign in / Sign up

Export Citation Format

Share Document