scholarly journals Bone geometry is altered by follistatin‐induced muscle growth in young adult male mice

JBMR Plus ◽  
2021 ◽  
Author(s):  
Audrey S.M. Chan ◽  
Narelle E. McGregor ◽  
Ingrid J. Poulton ◽  
Justin P. Hardee ◽  
Ellie H‐J Cho ◽  
...  
Keyword(s):  
Young Adult ◽  
Adult Male ◽  
Muscle Growth ◽  
Bone Geometry ◽  
Male Mice ◽  
Young Adult Male

Vitamin E improves bone quality in the aged but not in young adult male mice

2002 ◽  
Vol 13 (9) ◽  
pp. 543-549 ◽  
Author(s):  
Bahram H. Arjmandi ◽  
Shanil Juma ◽  
Alison Beharka ◽  
Mahendra S. Bapna ◽  
Mohammed Akhter ◽  
...  
Keyword(s):  
Vitamin E ◽  
Young Adult ◽  
Bone Quality ◽  
Adult Male ◽  
Male Mice ◽  
Young Adult Male

Nutritional stress timing differentially programs cognitive abilities in young adult male mice

2020 ◽  
pp. 1-13
Author(s):  
Bruno G. Berardino ◽  
Fabricio Ballarini ◽  
Mariela Chertoff ◽  
Lionel M. Igaz ◽  
Eduardo T. Cánepa
Keyword(s):  
Young Adult ◽  
Adult Male ◽  
Cognitive Abilities ◽  
Nutritional Stress ◽  
Male Mice ◽  
Young Adult Male

scholarly journals Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice

2022 ◽  
Vol 23 (2) ◽  
pp. 675
Author(s):  
Kimberly K. Richardson ◽  
Wen Ling ◽  
Kimberly Krager ◽  
Qiang Fu ◽  
Stephanie D. Byrum ◽  
...  
Keyword(s):  
Young Adult ◽  
Bone Resorption ◽  
Bone Loss ◽  
Ionizing Radiation ◽  
Bone Mass ◽  
Adult Male ◽  
Osteoclast Differentiation ◽  
Mitochondrial Activity ◽  
Male Mice ◽  
Young Adult Male

The damaging effects of ionizing radiation (IR) on bone mass are well-documented in mice and humans and are most likely due to increased osteoclast number and function. However, the mechanisms leading to inappropriate increases in osteoclastic bone resorption are only partially understood. Here, we show that exposure to multiple fractions of low-doses (10 fractions of 0.4 Gy total body irradiation [TBI]/week, i.e., fractionated exposure) and/or a single exposure to the same total dose of 4 Gy TBI causes a decrease in trabecular, but not cortical, bone mass in young adult male mice. This damaging effect was associated with highly activated bone resorption. Both osteoclast differentiation and maturation increased in cultures of bone marrow-derived macrophages from mice exposed to either fractionated or singular TBI. IR also increased the expression and enzymatic activity of mitochondrial deacetylase Sirtuin-3 (Sirt3)—an essential protein for osteoclast mitochondrial activity and bone resorption in the development of osteoporosis. Osteoclast progenitors lacking Sirt3 exposed to IR exhibited impaired resorptive activity. Taken together, targeting impairment of osteoclast mitochondrial activity could be a novel therapeutic strategy for IR-induced bone loss, and Sirt3 is likely a major mediator of this effect.

scholarly journals Early gestational maternal low-protein diet diminishes hepatic response to fasting in young adult male mice

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Noriko Sato ◽  
Katsuko Sudo ◽  
Masayo Mori ◽  
Chihiro Imai ◽  
Masaaki Muramatsu ◽  
...  
Keyword(s):  
Young Adult ◽  
Adult Male ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Male Mice ◽  
Young Adult Male ◽  
Low Protein

Infected urachal duct cyst in a young adult male

2021 ◽  
Vol 22 ◽  
pp. 100975
Author(s):  
Ellen Duncan ◽  
Suneet Bhansali ◽  
Ee Tein Tay
Keyword(s):  
Young Adult ◽  
Adult Male ◽  
Duct Cyst ◽  
Young Adult Male
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