Treatment of microvascular invasion in hepatocellular carcinoma with drug‐loaded nanocomposite platform under synergistic effect of magnetic field/near‐infrared light

2021 ◽  
Author(s):  
Daren Liu ◽  
Jinhong Wu ◽  
Huanbing Zhu ◽  
Xiuliang Zhu ◽  
Yun Jin ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Hepatocellular Carcinoma ◽  
Synergistic Effect ◽  
Near Infrared ◽  
Microvascular Invasion ◽  
Infrared Light ◽  
Near Infrared Light

Near infrared light absorption in magnetic nanoemulsion under external magnetic field

2014 ◽  
Vol 323 ◽  
pp. 54-60 ◽  
Author(s):  
Surajit Brojabasi ◽  
V. Mahendran ◽  
B.B. Lahiri ◽  
John Philip
Keyword(s):  
Magnetic Field ◽  
External Magnetic Field ◽  
Light Absorption ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light

Near-Infrared Light Laser-Triggered Release of Doxorubicin and Sorafenib from TemperatureSensitive Liposomes for Synergistic Therapy of Hepatocellular Carcinoma

2020 ◽  
Vol 16 (9) ◽  
pp. 1381-1393
Author(s):  
Yuan Peng ◽  
Zhenwei Su ◽  
Xin Wang ◽  
Teng Wu ◽  
Hong Xiao ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Drug Release ◽  
Near Infrared ◽  
Infrared Light ◽  
Temperature Sensitive ◽  
Triggered Release ◽  
Near Infrared Light ◽  
Aqueous Core ◽  
Multiple Drugs ◽  
Nir Laser

Chemotherapy of hepatocellular carcinoma (HCC) is facing drug resistance, which leads to unsatisfactory therapeutic effect. Thus, a combination therapy using multiple drugs may overcome this challenge. The current study aims to realize a synergistic chemotherapy of HCC by using a near-infrared light (NIR) responsive nanocarrier to co-deliver the chemotherapeutic drug Doxorubicin (DOX) and molecular targeting agent Sorafenib (SF). The nanocarrier, which could effectively load DOX in its aqueous core while SF and IR-780 in its lipid bilayer, is fabricated from a temperature-sensitive liposome (TSL) modified with PF127. An efficient SF and DOX co-loading was achieved, and meanwhile the effective photothermal conversion of IR-780 under NIR laser may cause a disassembly of the liposome structure which may trigger a rapid drug release in tumor site, greatly boosting the synergetic chemotherapeutic effect. The NIR laser-triggered drug release and the synergistic anti-tumor effect were evaluated both in cell and animal experiments, which revealed that the PF127-modified TSL is a potent nanoplatform to improve the HCC treatment through co-delivering a drug combination.

An ordered copper nanowell-array film with near-perfect broadband absorption from ultraviolet to near-infrared light

2020 ◽  
Vol 59 (11) ◽  
pp. 110906
Author(s):  
Juan Shen ◽  
Yong Ren ◽  
Xinxin Zhu ◽  
Min Mao ◽  
Quan Zhou ◽  
...  
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Broadband Absorption

scholarly journals Recent Near-Infrared Light-Activated Nanomedicine toward Precision Cancer Therapy

2021 ◽  
Author(s):  
Xiaowei Luan ◽  
Yongchun Pan ◽  
Yanfeng Gao ◽  
Yujun Song
Keyword(s):  
Cancer Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Human Society ◽  
Near Infrared Light ◽  
History Of ◽  
The Universe

Light has witnessed the history of mankind and even the universe. It is of great significances to the life of human society, contributing to energy, agriculture, communication, and much more....

scholarly journals Au–ZnO Conjugated Black Phosphorus as a Near-Infrared Light-Triggering and Recurrence-Suppressing Nanoantibiotic Platform against Staphylococcus aureus

Pharmaceutics ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 52
Author(s):  
Atanu Naskar ◽  
Sohee Lee ◽  
Kwang-sun Kim
Keyword(s):  
Staphylococcus Aureus ◽  
Bacterial Infections ◽  
Near Infrared ◽  
Au Nanoparticles ◽  
Synthesis Method ◽  
Antibacterial Properties ◽  
Black Phosphorus ◽  
Infrared Light ◽  
Resistant Bacteria ◽  
Near Infrared Light

Antibiotic therapy is the gold standard for bacterial infections treatment. However, the rapid increase in multidrug-resistant (MDR) bacterial infections and its recent use for secondary bacterial infections in many COVID-19 patients has considerably weakened its treatment efficacy. These shortcomings motivated researchers to develop new antibacterial materials, such as nanoparticle-based antibacterial platform with the ability to increase the chances of killing MDR strains and prevent their drug resistance. Herein, we report a new black phosphorus (BP)-based non-damaging near-infrared light-responsive platform conjugated with ZnO and Au nanoparticles as a synergistic antibacterial agent against Staphylococcus aureus species. First, BP nanosheets containing Au nanoparticles were assembled in situ with the ZnO nanoparticles prepared by a low-temperature solution synthesis method. Subsequently, the antibacterial activities of the resulting Au–ZnO–BP nanocomposite against the non-resistant, methicillin-resistant, and erythromycin-resistant S. aureus species were determined, after its photothermal efficacy was assessed. The synthesized nanocomposite exhibited excellent anti-S. aureus activity and good photothermal characteristics. The non-resistant S. aureus species did not produce drug-resistant bacteria after the treatment of multiple consecutive passages under the pressure of the proposed nanoantibiotic, but rapidly developed resistance to erythromycin. This work clearly demonstrates the excellent photothermal antibacterial properties of Au–ZnO–BP nanocomposite against the MDR S. aureus species.

π-Conjugated Copolymers Composed of Boron Formazanate and Their Application for a Wavelength Converter to Near-Infrared Light

2021 ◽  
Vol 54 (4) ◽  
pp. 1934-1942
Author(s):  
Yuki Kawano ◽  
Yoshinori Ito ◽  
Shunichiro Ito ◽  
Kazuo Tanaka ◽  
Yoshiki Chujo
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Wavelength Converter ◽  
Near Infrared Light ◽  
Conjugated Copolymers
Sign in / Sign up

Export Citation Format

Share Document