Biosafety and biodegradation studies of AZ31B magnesium alloy carotid artery stent in vitro and in vivo

2021 ◽  
Author(s):  
Deniz Eren Erişen ◽  
Yuqi Zhang ◽  
Bingchun Zhang ◽  
Ke Yang ◽  
Shanshan Chen ◽  
...  
Keyword(s):  
Magnesium Alloy ◽  
Carotid Artery ◽  
Az31b Magnesium Alloy ◽  
Carotid Artery Stent

Dynamic behaviors of a Ca–P coated AZ31B magnesium alloy during in vitro and in vivo degradations

2011 ◽  
Vol 176 (20) ◽  
pp. 1718-1726 ◽  
Author(s):  
Qiang Wang ◽  
Lili Tan ◽  
Wenli Xu ◽  
Bingchun Zhang ◽  
Ke Yang
Keyword(s):  
Magnesium Alloy ◽  
Az31b Magnesium Alloy ◽  
Dynamic Behaviors

scholarly journals Microstructure and surface texture driven improvement in in-vitro response of laser surface processed AZ31B magnesium alloy

2021 ◽  
Author(s):  
Tso-Chang Wu ◽  
Sameehan S. Joshi ◽  
Yee-Hsien Ho ◽  
Mangesh V. Pantawane ◽  
Subhasis Sinha ◽  
...  
Keyword(s):  
Magnesium Alloy ◽  
Surface Texture ◽  
Laser Surface ◽  
Az31b Magnesium Alloy ◽  
In Vitro Response

scholarly journals Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow

Blood ◽  
2010 ◽  
Vol 116 (15) ◽  
pp. e66-e73 ◽  
Author(s):  
Chih-Wen Ni ◽  
Haiwei Qiu ◽  
Amir Rezvan ◽  
Kihwan Kwon ◽  
Douglas Nam ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Ex Vivo ◽  
Expression Profiles ◽  
Quantitative Polymerase Chain Reaction ◽  
Gene Expression Profiles ◽  
Disturbed Flow ◽  
A Genome ◽  
Pattern Comparison

Abstract Recently, we showed that disturbed flow caused by a partial ligation of mouse carotid artery rapidly induces atherosclerosis. Here, we identified mechanosensitive genes in vivo through a genome-wide microarray study using mouse endothelial RNAs isolated from the flow-disturbed left and the undisturbed right common carotid artery. We found 62 and 523 genes that changed significantly by 12 hours and 48 hours after ligation, respectively. The results were validated by quantitative polymerase chain reaction for 44 of 46 tested genes. This array study discovered numerous novel mechanosensitive genes, including Lmo4, klk10, and dhh, while confirming well-known ones, such as Klf2, eNOS, and BMP4. Four genes were further validated for protein, including LMO4, which showed higher expression in mouse aortic arch and in human coronary endothelium in an asymmetric pattern. Comparison of in vivo, ex vivo, and in vitro endothelial gene expression profiles indicates that numerous in vivo mechanosensitive genes appear to be lost or dysregulated during culture. Gene ontology analyses show that disturbed flow regulates genes involved in cell proliferation and morphology by 12 hours, followed by inflammatory and immune responses by 48 hours. Determining the functional importance of these novel mechanosensitive genes may provide important insights into understanding vascular biology and atherosclerosis.

In vitro and in vivo biocompatibility and corrosion behaviour of a bioabsorbable magnesium alloy coated with octacalcium phosphate and hydroxyapatite

2015 ◽  
Vol 11 ◽  
pp. 520-530 ◽  
Author(s):  
Sachiko Hiromoto ◽  
Motoki Inoue ◽  
Tetsushi Taguchi ◽  
Misao Yamane ◽  
Naofumi Ohtsu
Keyword(s):  
Magnesium Alloy ◽  
Corrosion Behaviour ◽  
Octacalcium Phosphate

In vitro study on degradation of AZ31B magnesium alloy with fluoride conversion coating

2016 ◽  
Vol 32 (7) ◽  
pp. 409-414 ◽  
Author(s):  
Q. Li ◽  
P. Zhu ◽  
S. Chen ◽  
B. Zhang ◽  
K. Yang
Keyword(s):  
Magnesium Alloy ◽  
In Vitro Study ◽  
Conversion Coating ◽  
Vitro Study ◽  
Az31b Magnesium Alloy

Features of in vitro and in vivo behaviour of magnesium alloy WE43

2018 ◽  
Vol 215 ◽  
pp. 308-311 ◽  
Author(s):  
Elena Lukyanova ◽  
Natalia Anisimova ◽  
Natalia Martynenko ◽  
Mikhail Kiselevsky ◽  
Sergey Dobatkin ◽  
...  
Keyword(s):  
Magnesium Alloy ◽  
Alloy We43

In vitro and in vivo studies on the degradation and biosafety of Mg-Zn-Ca-Y alloy hemostatic clip with the carotid artery of SD rat model

2020 ◽  
Vol 115 ◽  
pp. 111093
Author(s):  
Xiao Yu ◽  
Dongyang Li ◽  
Yuanchao Liu ◽  
Pengfei Ding ◽  
Xianghui He ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Rat Model ◽  
In Vivo Studies ◽  
Sd Rat
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