Rapid endothelialization and controlled smooth muscle regeneration by electrospun heparin‐loaded polycaprolactone/gelatin hybrid vascular grafts

2018 ◽  
Vol 107 (6) ◽  
pp. 2040-2049 ◽  
Author(s):  
Jie Shi ◽  
Siyuan Chen ◽  
Lina Wang ◽  
Xiangyun Zhang ◽  
Jingchen Gao ◽  
...  
RSC Advances ◽  
2017 ◽  
Vol 7 (67) ◽  
pp. 42579-42589 ◽  
Author(s):  
Dongdong Xiao ◽  
Qiong Wang ◽  
Hao Yan ◽  
An Qin ◽  
Xiangguo Lv ◽  
...  

Asymmetric bilayer chitosan promoted bladder reconstruction with enhanced smooth muscle regeneration and angiogenesis, and functional restoration with augmented bladder capacity.


2011 ◽  
Vol 9 (02) ◽  
pp. 107-110 ◽  
Author(s):  
Atsushi Ishida ◽  
Moses Wu ◽  
Qun Shi ◽  
Yuji Fujita ◽  
Lester Sauvage ◽  
...  

2017 ◽  
Vol 26 (11) ◽  
pp. 1780-1791 ◽  
Author(s):  
Marta Pokrywczynska ◽  
Arkadiusz Jundzill ◽  
Karolina Warda ◽  
Lukasz Buchholz ◽  
Marta Rasmus ◽  
...  

2014 ◽  
Vol 62 (4) ◽  
pp. 429-438
Author(s):  
Péter Csébi ◽  
Csaba Jakab ◽  
Attila Patonai ◽  
Attila Arany-Tóth ◽  
László Kóbori ◽  
...  

Although experimental autologous patch or tubular conduit vascular grafts made from the internal rectus fascia sheath (IRFS) have been reported in the literature, thorough morphological evaluation and verification of the histological arterialisation of such grafts are lacking. Four purpose-bred Beagle dogs were utilised to create eight arterial internal rectus fascia sheath (ARFS) grafts implanted between bisected ends of the external iliac arteries. Four out of the eight ARFS grafts were patent after three months. Haematoxylin-eosin and Azan staining verified that the grafts gained a vessel-like layered structure with the presence of large amounts of collagen fibres. Although the inner surface of the intact IRFS was originally covered with claudin-5-negative and pancytokeratin-positive mesothelial cells in control samples, the internal cells of the ARFS grafts became claudin-5 positive and pancytokeratin negative like in intact arteries. Spindle-shaped cells of the wall of ARFS grafts were α-smooth muscle actin (α-SMA) positive just like the smooth muscle cells of intact arteries, but α-SMA immunoreactivity was negative in the intact IRFS. According to these findings, the fibroblast cells of the ARFS graft have changed into myofibroblast cells. The study has proved that ARFS grafts may be used as an alternative in arterial replacement, since the graft becomes morphologically and functionally similar to the host vessel via arterialisation.


2004 ◽  
Vol 18 (10) ◽  
pp. 982-988 ◽  
Author(s):  
Jamil Rehman ◽  
Maged M. Ragab ◽  
Ramakrishna Venkatesh ◽  
Chandru P. Sundaram ◽  
S. Ali Khan ◽  
...  

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