Increasing the tissue thickness at implant sites using guided bone regeneration and an additional collagen matrix: Histologic observations in beagle dogs

2018 ◽  
Vol 107 (3) ◽  
pp. 741-749 ◽  
Author(s):  
Gi-Young Seo ◽  
Daniel Stefan Thoma ◽  
Ui-Won Jung ◽  
Jung-Seok Lee
1998 ◽  
Vol 9 (5) ◽  
pp. 303-312 ◽  
Author(s):  
Gérard Brunel ◽  
Edmond Benqué ◽  
Frédéric Elharar ◽  
Catherine Sansac ◽  
Jean François Duffort ◽  
...  

2019 ◽  
Vol 8 (5) ◽  
pp. 618 ◽  
Author(s):  
Manuel Fernández-Domínguez ◽  
Victor Ortega-Asensio ◽  
Elena Fuentes Numancia ◽  
Juan Aragoneses ◽  
Horia Barbu ◽  
...  

The aim of this experimental animal study was to assess guided bone regeneration (GBR) and implant stability (ISQ) around two dental implants with different macrogeometries. Forty eight dental implants were placed within six Beagle dogs. The implants were divided into two groups (n = 24 per group): G1 group implants presented semi-conical macrogeometry, a low apical self-tapping portion, and an external hexagonal connection (whereby the cervical portion was bigger than the implant body). G2 group implants presented parallel walls macrogeometry, a strong apical self-tapping portion, and an external hexagonal connection (with the cervical portion parallel to the implant body). Buccal (mouth-related) defects of 2 mm (c2 condition) and 5 mm (c3 condition) were created. For the control condition with no defect (c1), implants were installed at crestal bone level. Eight implants in each group were installed under each condition. The implant stability quotient (ISQ) was measured immediately after implant placement, and on the day of sacrifice (3 months after the implant placement). Histological and histomorphometric procedures and analysis were performed to assess all samples, measuring crestal bone loss (CBL) and bone-to-implant contact (BIC). The data obtained were compared with statistical significance set at p < 0.05. The ISQ results showed a similar evolution between the groups at the two evaluation times, although higher values were found in the G1 group under all conditions. Within the limitations of this animal study, it may be concluded that implant macrogeometry is an important factor influencing guided bone regeneration in buccal defects. Group G1 showed better buccal bone regeneration (CBL) and BIC % at 3 months follow up, also parallel collar design can stimulate bone regeneration more than divergent collar design implants. The apical portion of the implant, with a stronger self-tapping feature, may provide better initial stability, even in the presence of a bone defect in the buccal area.


Polymers ◽  
2015 ◽  
Vol 7 (10) ◽  
pp. 2061-2077 ◽  
Author(s):  
Jin-Hyung Shim ◽  
Joo-Yun Won ◽  
Su-Jin Sung ◽  
Dong-Hyuk Lim ◽  
Won-Soo Yun ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Peer W. Kämmerer ◽  
Malte Scholz ◽  
Maria Baudisch ◽  
Jan Liese ◽  
Katharina Wegner ◽  
...  

Introduction. The aim of the study was an evaluation of different approaches for guided bone regeneration (GBR) of peri-implant defects in an in vivo animal model. Materials and Methods. In minipigs (n=15), peri-implant defects around calcium phosphate- (CaP-; n=46) coated implants were created and randomly filled with (1) blank, (2) collagen/hydroxylapatite/β-tricalcium phosphate scaffold (CHT), (3) CHT + growth factor cocktail (GFC), (4) jellyfish collagen matrix, (5) jellyfish collagen matrix + GFC, (6) collagen powder, and (7) collagen powder + periodontal ligament stem cells (PDLSC). Additional collagen membranes were used for coverage of the defects. After 120 days of healing, bone growth was evaluated histologically (bone to implant contact (BIC;%)), vertical bone apposition (VBA; mm), and new bone height (NBH; %). Results. In all groups, new bone formation was seen. Though, when compared to the blank group, no significant differences were detected for all parameters. BIC and NBH in the group with collagen matrix as well as the group with the collagen matrix + GFC were significantly less when compared to the collagen powder group (all: p<0.003). Conclusion. GBR procedures, in combination with CaP-coated implants, will lead to an enhancement of peri-implant bone growth. There was no additional significant enhancement of osseous regeneration when using GFC or PDLSC.


2012 ◽  
Vol 23 (3) ◽  
pp. e186-e189 ◽  
Author(s):  
Daniele De Santis ◽  
Alessandro Cucchi ◽  
Antonio de Gemmis ◽  
Francesco Nocini Pier

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