Lithium doped calcium phosphate cement maintains physical mechanical properties and promotes osteoblast proliferation and differentiation

2016 ◽  
Vol 105 (5) ◽  
pp. 944-952 ◽  
Author(s):  
Li Li ◽  
Renchong Wang ◽  
Baichuan Li ◽  
Wei Liang ◽  
Haobo Pan ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Osteoblast Proliferation ◽  
Proliferation And Differentiation

The Effect of Cefazolin on Mechanical Properties and Antibacterial Reactions of Calcium Phosphate Cement

2011 ◽  
Vol 46 (4) ◽  
pp. 273
Author(s):  
Ki-Dae Kwon ◽  
Jae-Suk Chang ◽  
Soo-Ho Lee ◽  
Dong-Ho Lee ◽  
Kang-Sik Lee ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Calcium Phosphate Cement

Effect of Methotrexate on the Mechanical Properties and Microstructure of Calcium Phosphate Cement

Orthopedics ◽  
2014 ◽  
Vol 37 (10) ◽  
pp. e906-e910 ◽  
Author(s):  
Guangjun Liao ◽  
Dongxiu Sun ◽  
Jian Han ◽  
Jiangwei Tan
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Calcium Phosphate Cement

Vertebroplasty in Goat Model Using Macroporous Calcium Phosphate Cement (MCPC®)

2007 ◽  
Vol 361-363 ◽  
pp. 377-380
Author(s):  
Xavier Bourges ◽  
Serge Baroth ◽  
Eric Goyenvalle ◽  
Ronan Cognet ◽  
Françoise Moreau ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Mechanical Property ◽  
Calcium Phosphate ◽  
Compression Test ◽  
Invasive Surgery ◽  
Calcium Phosphate Cement ◽  
Bone Ingrowth ◽  
Cement Matrix

We performed vertebroplasty on goat model by injecting a new macroporous calcium phosphate cement MCPC®. The mechanical property of the cement is about 12MPa after 24 hours (compression test). The cement matrix is totally transformed into poorly crystallized apatite in 48 hours. This study demonstrates that MCPC cement was suitable and efficient for a spine application. Its injectability allows to be used in mini invasive surgery and its mechanical properties are compatible to support spine strength. In addition, a bone ingrowth onto the BCP granules occurred with time.

Biomimetic Mineralization and Bioactivity of Phosphorylated Chitosan

2005 ◽  
Vol 288-289 ◽  
pp. 429-432 ◽  
Author(s):  
Zhi Qing Chen ◽  
Quan Li Li ◽  
Quan Zen ◽  
Gang Li ◽  
Hao Bin Jiang ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Crystal Nucleation ◽  
Osteoblast Proliferation ◽  
Biomimetic Mineralization ◽  
P Content ◽  
Proliferation And Differentiation ◽  
Nucleation Growth

Phosphorylated chitosans were synthesized as templates to manipulate hydroxyapatite (HA) crystal nucleation, growth and microstructure. Two kinds of insoluble phosphorylated chitosan were soaked in saturated Ca(OH)2 solution for 4 d and in 1.5× SBF (simulated body fluid) solutions for 14 d at 37 °C for biomimetic mineralization. A lower [P]-content of phosphorylated chitosan promoted greater mineralization than higher [P]-content. Phosphorylated chitosan inhibited osteoblast proliferation and differentiation in vitro, while calcium phosphate phosphorylated chitosan composites did not.

Mechanical properties of the femur filled with calcium phosphate cement under torsional loading: a model in rabbits

2002 ◽  
Vol 7 (5) ◽  
pp. 562-569 ◽  
Author(s):  
Hiroo Mizobuchi ◽  
Toshikazu Tani ◽  
Ryuichi Takemasa ◽  
Hiroshi Yamamoto ◽  
Hiroshi Sonobe
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Torsional Loading

Macroporous Calcium Phosphate Cement (MCPC®) for Bone Reconstruction in Cranioplasty: Animal Study Performance

2008 ◽  
Vol 396-398 ◽  
pp. 245-248
Author(s):  
Xavier Bourges ◽  
Eric Aguado ◽  
Eric Goyenvalle ◽  
Serge Baroth ◽  
G. Daculsi
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Bone Ingrowth ◽  
Parietal Bone ◽  
Cement Matrix ◽  
Bone Reconstruction ◽  
Reconstruction Surgery ◽  
Powder Component ◽  
Study Performance

We have developed a novel macroporous calcium phosphate cement MCPC® that sets to poorly crystalline apatite after mixing the powder component with an aqueous solution and has interconnective macroporosity We performed cranioplasty on rat model by injecting the new macroporous calcium phosphate cement MCPC®. The mechanical property of the cement is about 12MPa after 24 hours (compression test). The cement matrix is totally transformed into poorly crystalline apatite in 48 hours. This study demonstrates that MCPC® cement was suitable and efficient for parietal bone reconstruction. Its injectability and moldability allows to be used in bone reconstruction surgery and its mechanical properties are compatible to support calvarial reconstruction. In addition, a bone ingrowth onto the BCP granules occurred on time.

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