scholarly journals Keratin hydrogel carrier system for simultaneous delivery of exogenous growth factors and muscle progenitor cells

2015 ◽  
Vol 104 (5) ◽  
pp. 864-879 ◽  
Author(s):  
Seth Tomblyn ◽  
Elizabeth L. Pettit Kneller ◽  
Stephen J. Walker ◽  
Mary D. Ellenburg ◽  
Christine J. Kowalczewski ◽  
...  
Keyword(s):  
Growth Factors ◽  
Progenitor Cells ◽  
Carrier System ◽  
Exogenous Growth ◽  
Muscle Progenitor Cells ◽  
Exogenous Growth Factors ◽  
Simultaneous Delivery

scholarly journals Dynamic mechanical loading and growth factors influence chondrogenesis of induced pluripotent mesenchymal progenitor cells in a cartilage-mimetic hydrogel

2019 ◽  
Vol 7 (12) ◽  
pp. 5388-5403
Author(s):  
Elizabeth A. Aisenbrey ◽  
Ganna Bilousova ◽  
Karin Payne ◽  
Stephanie J. Bryant
Keyword(s):  
Growth Factors ◽  
Progenitor Cells ◽  
Mechanical Loading ◽  
Mesenchymal Progenitor Cells ◽  
Dynamic Mechanical ◽  
Exogenous Growth ◽  
Induced Pluripotent ◽  
Exogenous Growth Factors ◽  
Biophysical Cues

The chondrogenesis of iPSC-mesenchymal progenitor cells in a cartilage mimetic hydrogel is dependent on the combinatory effects of biophysical cues and exogenous growth factors.

Apical Papilla Cells Are Capable of Forming a Pulplike Tissue with Odontoblastlike Cells without the Use of Exogenous Growth Factors

2018 ◽  
Vol 44 (11) ◽  
pp. 1671-1676 ◽  
Author(s):  
Cibele Pelissari ◽  
Adriana F.C. Paris ◽  
Andrea Mantesso ◽  
Marília Trierveiler
Keyword(s):  
Growth Factors ◽  
Exogenous Growth ◽  
Apical Papilla ◽  
Exogenous Growth Factors

Protein-engineered microenvironments can promote endothelial differentiation of human mesenchymal stem cells in the absence of exogenous growth factors

2016 ◽  
Vol 4 (12) ◽  
pp. 1761-1772 ◽  
Author(s):  
Yeji Kim ◽  
Julie C. Liu
Keyword(s):  
Stem Cells ◽  
Endothelial Cells ◽  
Mesenchymal Stem Cells ◽  
Growth Factors ◽  
Human Mesenchymal Stem Cells ◽  
Endothelial Differentiation ◽  
P Protein ◽  
Exogenous Growth ◽  
Exogenous Growth Factors

Protein-based microenvironments are promising tools to obtain endothelial cells since they promote hMSC differentiation without exogenous VEGF.

scholarly journals Differential responsiveness of myc- and ras-transfected cells to growth factors: selective stimulation of myc-transfected cells by epidermal growth factor.

1986 ◽  
Vol 6 (3) ◽  
pp. 870-877 ◽  
Author(s):  
D F Stern ◽  
A B Roberts ◽  
N S Roche ◽  
M B Sporn ◽  
R A Weinberg
Keyword(s):  
Growth Factors ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Soft Agar ◽  
Tgf Beta ◽  
Transfected Cells ◽  
Exogenous Growth ◽  
Epidermal Growth ◽  
Ras Oncogenes ◽  
Exogenous Growth Factors

To identify functional relationships between oncogenes and growth factors, we compared the effects of transfected myc and ras oncogenes on the responsiveness of Fischer rat 3T3 cells to three growth factors: epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and transforming growth factor-beta (TGF-beta). Control cells did not grow in soft agar under any conditions. ras-Transfected cells grew in soft agar under all conditions tested and were insensitive to the stimulatory effects of exogenous growth factors. These cells secreted elevated levels of both EGF-like factors and TGF-beta, suggesting that the lack of responsiveness of these cells to exogenous growth factors arose from autocrine stimulation. myc-Transfected cells displayed conditional anchorage-independent growth: they formed numerous colonies in soft agar in the presence of EGF but relatively few colonies in the presence of PDGF or TGF-beta. Secretion of EGF-like factors and TGF-beta by these cells was not elevated above that of control cells. These results suggest a model for the mechanism of cooperation between myc and ras oncogenes in which ras-like genes induce growth factor production, while myc-like genes increase the responsiveness of cells to these factors.

The cartilage matrix molecule components produced by human foetal cartilage rudiment cells within scaffolds and the role of exogenous growth factors

Biomaterials ◽  
2012 ◽  
Vol 33 (16) ◽  
pp. 4078-4088 ◽  
Author(s):  
Christine Y. Chuang ◽  
Kifah Shahin ◽  
Megan S. Lord ◽  
James Melrose ◽  
Pauline M. Doran ◽  
...  
Keyword(s):  
Growth Factors ◽  
Cartilage Matrix ◽  
Matrix Molecule ◽  
Exogenous Growth ◽  
Exogenous Growth Factors
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