Long-term animal implantation study of biotube-autologous small-caliber vascular graft fabricated by in-body tissue architecture

2011 ◽  
Vol 98B (1) ◽  
pp. 120-126 ◽  
Author(s):  
Taiji Watanabe ◽  
Keiichi Kanda ◽  
Masashi Yamanami ◽  
Hatsue Ishibashi-Ueda ◽  
Hitoshi Yaku ◽  
...  
Keyword(s):  
Vascular Graft ◽  
Body Tissue ◽  
Tissue Architecture ◽  
Animal Implantation

Long-term outcomes of patch tracheoplasty using collagenous tissue membranes (biosheets) produced by in-body tissue architecture in a beagle model

Surgery Today ◽  
2019 ◽  
Vol 49 (11) ◽  
pp. 958-964
Author(s):  
Satoshi Umeda ◽  
Yasuhide Nakayama ◽  
Takeshi Terazawa ◽  
Ryosuke Iwai ◽  
Shohei Hiwatashi ◽  
...  
Keyword(s):  
Body Tissue ◽  
Tissue Architecture ◽  
Long Term Outcomes ◽  
Collagenous Tissue

scholarly journals Tissue ingrowth markedly reduces mechanical anisotropy and stiffness in fibre direction of highly aligned electrospun polyurethane scaffolds

2019 ◽  
Author(s):  
Hugo Krynauw ◽  
Jannik Buescher ◽  
Josepha Koehne ◽  
Loes Verrijt ◽  
Georges Limbert ◽  
...  
Keyword(s):  
Elastic Modulus ◽  
Vascular Graft ◽  
Small Diameter ◽  
Mechanical Anisotropy ◽  
Fibre Direction ◽  
Tissue Ingrowth ◽  
Fibre Alignment ◽  
Random Fibre ◽  
Directed Research

AbstractPurposeThe lack of long-term patency of synthetic vascular grafts currently available on the market has directed research towards improving the performance of small diameter grafts. Improved radial compliance matching and tissue ingrowth into the graft scaffold are amongst the main goals for an ideal vascular graft.MethodsBiostable polyurethane scaffolds were manufactured by electrospinning and implanted in subcutaneous and circulatory positions in the rat for 7, 14 and 28 days. Scaffold morphology, tissue ingrowth, and mechanical properties of the scaffolds were assessed before implantation and after retrieval.ResultsTissue ingrowth after 24 days was 96.5 ± 2.3% in the subcutaneous implants and 77.8 ± 5.4% in the circulatory implants. Over the 24 days implantation, the elastic modulus at 12% strain decreased by 59% in direction of the fibre alignment whereas it increased by 1379% transverse to the fibre alignment of the highly aligned scaffold of the subcutaneous implants. The lesser aligned scaffold of the circulatory graft implants exhibited an increase of the elastic modulus at 12% strain by 77% in circumferential direction.ConclusionBased on the observations, it is proposed that the mechanism underlying the softening of the highly aligned scaffold in the predominant fibre direction is associated with scaffold compaction and local displacement of fibres by the newly formed tissue. The stiffening of the scaffold, observed transverse to highly aligned fibres and for more a random fibre distribution, represents the actual mechanical contribution of the tissue that developed in the scaffold.

scholarly journals Long-term Functioning Aneurysmal Free Tissue-engineered Vascular Graft Based on Composite Bi-layered (PLLA/FPL) Scaffold

2019 ◽  
Vol 58 (6) ◽  
pp. e817-e818 ◽  
Author(s):  
Guriy Popov ◽  
Valeriy Vavilov ◽  
Galina Yukina ◽  
Pavel Popryadukhin ◽  
Irina Dobrovolskaya ◽  
...  
Keyword(s):  
Vascular Graft

scholarly journals Endovascular rescue of long-term vascular graft implants and need for continuous surveillance

2018 ◽  
Vol 4 (1) ◽  
pp. 12-14
Author(s):  
Brian M. Leoce ◽  
Herbert Dardik ◽  
Phillip Bahramipour ◽  
Thomas R. Bernik
Keyword(s):  
Vascular Graft

scholarly journals Long-term patency of small-diameter vascular graft made from fibroin, a silk-based biodegradable material

2010 ◽  
Vol 51 (1) ◽  
pp. 155-164 ◽  
Author(s):  
Soichiro Enomoto ◽  
Makoto Sumi ◽  
Kan Kajimoto ◽  
Yasumoto Nakazawa ◽  
Rui Takahashi ◽  
...  
Keyword(s):  
Vascular Graft ◽  
Small Diameter ◽  
Biodegradable Material

Vascular graft infections:In vitro andin vivo investigations of a new vascular graft with long-term protection

2005 ◽  
Vol 74B (1) ◽  
pp. 601-607 ◽  
Author(s):  
Torsten Ueberrueck ◽  
Roland Zippel ◽  
Joerg Tautenhahn ◽  
Ingo Gastinger ◽  
Hans Lippert ◽  
...  
Keyword(s):  
Vascular Graft
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