In vitro performance assessment of new brushite-forming Zn- and ZnSr-substituted β-TCP bone cements

2010 ◽  
pp. n/a-n/a ◽  
Author(s):  
S. Pina ◽  
S.I. Vieira ◽  
P. M. C. Torres ◽  
F. Goetz-Neunhoeffer ◽  
J. Neubauer ◽  
...  
Keyword(s):  
Performance Assessment ◽  
Bone Cements ◽  
In Vitro Performance

scholarly journals Risk based in vitro performance assessment of extended release abuse deterrent formulations

2016 ◽  
Vol 500 (1-2) ◽  
pp. 255-267 ◽  
Author(s):  
Xiaoming Xu ◽  
Abhay Gupta ◽  
Manar Al-Ghabeish ◽  
Silvia N. Calderon ◽  
Mansoor A. Khan
Keyword(s):  
Performance Assessment ◽  
Extended Release ◽  
In Vitro Performance

In Vitro Performance Assessment of Tubular Membrane Oxygenators

1980 ◽  
Vol 8 (4) ◽  
pp. 309-332
Author(s):  
Hai Le-Phat ◽  
John Awad ◽  
Robert Guidoin ◽  
Roger Bibaud ◽  
Roland Picard ◽  
...  
Keyword(s):  
Performance Assessment ◽  
Tubular Membrane ◽  
Membrane Oxygenators ◽  
In Vitro Performance

scholarly journals In vitro performance assessment of new beta Ti–Mo–Nb alloy compositions

2015 ◽  
Vol 47 ◽  
pp. 105-113 ◽  
Author(s):  
Patricia Neacsu ◽  
Doina-Margareta Gordin ◽  
Valentina Mitran ◽  
Thierry Gloriant ◽  
Marieta Costache ◽  
...  
Keyword(s):  
Performance Assessment ◽  
In Vitro Performance

scholarly journals In VitroActivities of Daptomycin-, Vancomycin-, and Teicoplanin-Loaded Polymethylmethacrylate against Methicillin-Susceptible, Methicillin-Resistant, and Vancomycin-Intermediate Strains of Staphylococcus aureus

2011 ◽  
Vol 55 (12) ◽  
pp. 5480-5484 ◽  
Author(s):  
Yuhan Chang ◽  
Wen-Chien Chen ◽  
Pang-Hsin Hsieh ◽  
Dave W. Chen ◽  
Mel S. Lee ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
High Performance ◽  
Low Dose ◽  
Antibacterial Activities ◽  
High Dose ◽  
Bone Cements ◽  
Antibacterial Effects ◽  
Methicillin Resistant ◽  
Content Type

ABSTRACTThe objective of this study was to evaluate the antibacterial effects of polymethylmethacrylate (PMMA) bone cements loaded with daptomycin, vancomycin, and teicoplanin against methicillin-susceptibleStaphylococcus aureus(MSSA), methicillin-resistantStaphylococcus aureus(MRSA), and vancomycin-intermediateStaphylococcus aureus(VISA) strains. Standardized cement specimens made from 40 g PMMA loaded with 1 g (low-dose), 4 g (middle-dose) or 8 g (high-dose) antibiotics were tested for elution characteristics and antibacterial activities. The patterns of release of antibiotics from the cement specimens were evaluated usingin vitrobroth elution assay with high-performance liquid chromatography. The activities of broth elution fluid against differentStaphylococcus aureusstrains (MSSA, MRSA, and VISA) were then determined. The antibacterial activities of all the tested antibiotics were maintained after being mixed with PMMA. The cements loaded with higher dosages of antibiotics showed longer elution periods. Regardless of the antibiotic loading dose, the teicoplanin-loaded cements showed better elution efficacy and provided longer inhibitory periods against MSSA, MRSA, and VISA than cements loaded with the same dose of vancomycin or daptomycin. Regarding the choice of antibiotics for cement loading in the treatment ofStaphylococcus aureusinfection, teicoplanin was superior in terms of antibacterial effects.

In Vitro Cytotoxicity Testing of Wood-Based Biomorphic SiC Ceramics

2005 ◽  
Vol 284-286 ◽  
pp. 581-584 ◽  
Author(s):  
Alejandro de Carlos ◽  
Jacinto P. Borrajo ◽  
Julia Serra ◽  
Pio González ◽  
Sara Liste ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
In Vitro Cytotoxicity ◽  
Cellular Activity ◽  
Sic Ceramics ◽  
Cellular Attachment ◽  
Sic Ceramic ◽  
Extraction Test ◽  
Innovative Material ◽  
In Vitro Performance

The aim of this study was to test the in vitro cytotoxicity of wood-based biomorphic Silicon Carbide (SiC) ceramics, using MG-63 human osteoblast-like cells. This innovative material has been recently developed and it exhibits unique mechanical properties towards their application in biomedical technology. In the solvent extraction test the SiC ceramic extracts had almost no effect on cellular activity even at 100% concentration. A similar behaviour was found for Ti6Al4V and bioactive glass, used as reference materials. The results of the cell morphology and the cellular attachment response have also demonstrated that the in vitro performance of these biomorphic SiC ceramics is qualitatively comparable to that produced by titanium alloy and bioactive glass, which seems very promising.

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