scholarly journals Effect of particle size of an amorphous calcium phosphate filler on the mechanical strength and ion release of polymeric composites

2006 ◽  
Vol 80B (1) ◽  
pp. 11-17 ◽  
Author(s):  
Soo-Young Lee ◽  
W. F. Regnault ◽  
J. M. Antonucci ◽  
D. Skrtic
Keyword(s):  
Particle Size ◽  
Calcium Phosphate ◽  
Mechanical Strength ◽  
Amorphous Calcium Phosphate ◽  
Polymeric Composites ◽  
Ion Release ◽  
Effect Of Particle Size ◽  
Phosphate Filler

Amorphous Calcium Phosphate Based Polymeric Composites: Effects of Polymer Composition and Filler's Particle Size on Composite Properties

2005 ◽  
Vol 284-286 ◽  
pp. 737-740 ◽  
Author(s):  
Drago Skrtic ◽  
S.Y. Lee ◽  
Joseph M. Antonucci ◽  
D.W. Liu
Keyword(s):  
Particle Size ◽  
Calcium Phosphate ◽  
Physicochemical Properties ◽  
Amorphous Calcium Phosphate ◽  
Fine Tuning ◽  
Polymer Composition ◽  
Ion Release ◽  
The Matrix ◽  
Carboxylic Groups ◽  
Composite Properties

This study explores how a) the resin grafting potential for amorphous calcium phosphate (ACP) and b) particle size of ACP affects physicochemical properties of composites. Copolymers and composites were evaluated for biaxial flexure strength (BFS), degree of vinyl conversion (DC), mineral ion release and water sorption (WS). Milled ACP composites were superior to unmilled ACP composites and exhibited 62 % and 77 % higher BFS values (dry and wet state, respectively). The average DC of copolymers 24 h after curing was 80 %. DC of composites decreased 10.3 % for unmilled Zr-ACP and 4.6 % for milled Zr-ACP when compared to the corresponding copolymers. The WS increased as follows: copolymers < milled Zr-ACP composites < unmilled Zr-ACP composites. The levels of Ca and PO4 released from both types of composites increased with the increasing EBPADMA/TEGDMA ratio in the matrix. They were significantly above the minimum necessary for the redeposition of HAP to occur. No significant consumption of released calcium by the carboxylic groups of methacryloxyethyl phtahalate (MEP) occurred at a mass fraction of 2.6 % of MEP in the resin. Improvements in ACP composite’s physicochemical properties are achieved by fine tuning of the resin and improved ACP’s dispersion within the polymer matrix after ball-milling.

Synthesis and Properties of α-Tricalcium Phosphate from Amorphous Calcium Phosphate as Component for Bone Cements

2016 ◽  
Vol 721 ◽  
pp. 182-186
Author(s):  
Zilgma Irbe ◽  
Dagnija Loca ◽  
Agnese Pura ◽  
Liga Berzina-Cimdina
Keyword(s):  
Heat Treatment ◽  
Particle Size ◽  
Calcium Phosphate ◽  
Bone Defect ◽  
Tricalcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Heat Treating ◽  
Bone Cements ◽  
Important Ingredient ◽  
Reactive Particles

α-Tricalcium phosphate is an important ingredient of calcium phosphate bone cements, which are used for bone defect augmentation and repair. In this study sub-micrometre sized α­tricalcium phosphate particles were synthesized by heat treating amorphous calcium phosphate. Size of synthesized particles depended on duration and temperature of heat treatment. Longer duration and higher temperatures produced larger particles. The reactivity of synthesized particles did not correlate with particle size – the smallest particles did not have the highest reactivity. The most reactive particles were prepared at 700-800 °C. The prepared particles were more reactive than those of conventionally synthesized α-tricalcium phosphate.

scholarly journals Ultrasonic application and spray drying during amorphous calcium phosphate synthesis

2019 ◽  
Vol 8 (4) ◽  
pp. 711-714
Keyword(s):  
Electron Microscopy ◽  
Particle Size ◽  
Calcium Phosphate ◽  
Spray Drying ◽  
Amorphous Calcium Phosphate ◽  
Calcium Phosphates ◽  
Calcium Content ◽  
Synthesis Process ◽  
Particle Sizes ◽  
Ultrasound Application

Hydroxyapatite, amorphous calcium phosphates, calcium triphosphate and calcium octaphosphate are the main components present in bones and teeth. Calcium phosphates are easily synthesized, playing an important role in regenerative medicine, being able to be used as bone implants. There are different ways of synthesizing phosphates, the most commonly used being wet chemical method. The objective of this work was to study the influence of the use of ultrasound and spray drying on the synthesis of amorphous calcium phosphate. Two synthetic variants were studied. One without ultrasound application and the other with ultrasound application. The samples obtained were characterized by X-ray diffraction, FTIR spectroscopy and scanning electron microscopy. The particle size by electron microscopy and the calcium content by atomic absorption was determined. The results showed that when spray drying is applied, particle sizes of less than 261 nm are obtained in the samples synthesized without ultrasound application, being less than 59 nm in the samples synthesized with ultrasound application. The statistical analysis by ANOVA showed significant differences between the particle sizes of the samples synthesized without ultrasound application and the samples synthesized by applying ultrasound. In both cases the particles were spherical. The results obtained show that the application of ultrasound during the synthesis process decreases the particle size, increasing the surface area, which favors the spray drying process.

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