Bioreactor cultivation condition for engineered bone tissue: Effect of various bioreactor designs on extra cellular matrix synthesis

2020 ◽  
Vol 108 (8) ◽  
pp. 1662-1672 ◽  
Author(s):  
Hanieh Nokhbatolfoghahaei ◽  
Mahboubeh Bohlouli ◽  
Zahrasadat Paknejad ◽  
Maryam R. Rad ◽  
Leila M. Amirabad ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Extra Cellular Matrix ◽  
Cultivation Condition ◽  
Matrix Synthesis ◽  
Bioreactor Cultivation ◽  
Tissue Effect ◽  
Cellular Matrix

Effect of cyclic stretching and TGF-beta pathway on the extra cellular matrix synthesis in tissue engineering

2006 ◽  
Vol 39 ◽  
pp. S579
Author(s):  
A. Kadi ◽  
S. Fawzi-Grancher ◽  
G.L. Lakisic ◽  
N. De Isla ◽  
C. Huselstein ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Extra Cellular Matrix ◽  
Tgf Beta ◽  
Matrix Synthesis ◽  
Cyclic Stretching ◽  
Cellular Matrix

Extra cellular matrix remodelling in chronic cardiac allograft rejection

2011 ◽  
Vol 59 (S 01) ◽  
Author(s):  
M Franz ◽  
A Berndt ◽  
K Grün ◽  
D Neri ◽  
H Kosmehl ◽  
...  
Keyword(s):  
Allograft Rejection ◽  
Cardiac Allograft ◽  
Extra Cellular Matrix ◽  
Cardiac Allograft Rejection ◽  
Cellular Matrix

Altered Expression of Extra-Cellular Matrix Proteins and Integrin Receptors in Discoid Lupus Erythematosus

2004 ◽  
Vol 1 (4) ◽  
pp. 368-371
Author(s):  
Gianluigi Giannelli ◽  
Concetta Sgarra ◽  
Caterina Foti ◽  
Carlo Bergamini ◽  
Carmela Coviello ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Extra Cellular Matrix ◽  
Matrix Proteins ◽  
Discoid Lupus Erythematosus ◽  
Integrin Receptors ◽  
Altered Expression ◽  
Cellular Matrix

The Role of Cytokines in Interactions of Mesenchymal Stem Cells and Breast Cancer Cells

2020 ◽  
Vol 15 ◽  
Author(s):  
Hariharan Jayaraman ◽  
Nalinkanth V. Ghone ◽  
Ranjith Kumaran R ◽  
Himanshu Dashora
Keyword(s):  
Breast Cancer ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Tumor Microenvironment ◽  
Cancer Cells ◽  
Cell Communication ◽  
Extra Cellular Matrix ◽  
Cytokine Signaling ◽  
Cellular Matrix

: Mesenchymal stem cells because of its high proliferation, differentiation, regenerative capacity, and ease of availability have been a popular choice in cytotherapy. Mesenchymal Stem Cells (MSCs) have a natural tendency to home in a tumor microenvironment and acts against it, owing to the similarity of the latter to an injured tissue environment. Several studies have confirmed the recruitment of MSCs by tumor through various cytokine signaling that brings about phenotypic changes to cancer cells, thereby promoting migration, invasion, and adhesion of cancer cells. The contrasting results on MSCs as a tool for cancer cytotherapy may be due to the complex cell to cell interaction in the tumor microenvironment, which involves various cell types such as cancer cells, immune cells, endothelial cells, and cancer stem cells. Cell to cell communication can be simple or complex and it is transmitted through various cytokines among multiple cell phenotypes, mechano-elasticity of the extra-cellular matrix surrounding the cancer cells, and hypoxic environments. In this article, the role of the extra-cellular matrix proteins and soluble mediators that acts as communicators between mesenchymal stem cells and cancer cells has been reviewed specifically for breast cancer, as it is the leading member of cancer malignancies. The comprehensive information may be beneficial in finding a new combinatorial cytotherapeutic strategy using MSCs by exploiting the cross-talk between mesenchymal stem cells and cancer cells for treating breast cancer.

A NUMERICAL PROOF THAT CERTAIN CELLS FOLLOW THE TRAILS OF THE DIFFUSIONS OF SOME CHEMICALS IN THE EXTRACELLULAR MATRIX

2021 ◽  
pp. 2150027
Author(s):  
İREM ÇAY ◽  
SERDAL PAMUK
Keyword(s):  
Mathematical Model ◽  
Extracellular Matrix ◽  
Tumor Angiogenesis ◽  
Numerical Solutions ◽  
Extra Cellular Matrix ◽  
The Matrix ◽  
Good Agreement ◽  
Cellular Matrix

In this work, we obtain the numerical solutions of a 2D mathematical model of tumor angiogenesis originally presented in [Pamuk S, ÇAY İ, Sazci A, A 2D mathematical model for tumor angiogenesis: The roles of certain cells in the extra cellular matrix, Math Biosci 306:32–48, 2018] to numerically prove that the certain cells, the endothelials (EC), pericytes (PC) and macrophages (MC) follow the trails of the diffusions of some chemicals in the extracellular matrix (ECM) which is, in fact, inhomogeneous. This leads to branching, the sprouting of a new neovessel from an existing vessel. Therefore, anastomosis occurs between these sprouts. In our figures we do see these branching and anastomosis, which show the fact that the cells diffuse according to the structure of the ECM. As a result, one sees that our results are in good agreement with the biological facts about the movements of certain cells in the Matrix.

An injectable alginate/extra cellular matrix (ECM) hydrogel towards acellular treatment of heart failure

2018 ◽  
Vol 9 (1) ◽  
pp. 1-13 ◽  
Author(s):  
Clive J. Curley ◽  
Eimear B. Dolan ◽  
Matthias Otten ◽  
Svenja Hinderer ◽  
Garry P. Duffy ◽  
...  
Keyword(s):  
Heart Failure ◽  
Extra Cellular Matrix ◽  
Cellular Matrix

scholarly journals Correction: The 1ALCTL and 1BLCTL isoforms of Arg/Abl2 induce fibroblast activation and extra cellular matrix remodelling differently

Biology Open ◽  
2021 ◽  
Vol 10 (5) ◽  
Author(s):  
Barbara Torsello ◽  
Sofia De Marco ◽  
Silvia Bombelli ◽  
Elisa Chisci ◽  
Valeria Cassina ◽  
...  
Keyword(s):  
Extra Cellular Matrix ◽  
Fibroblast Activation ◽  
Cellular Matrix
Sign in / Sign up

Export Citation Format

Share Document