Enhanced osteogenic differentiation of mesenchymal stem cells on metal–organic framework based on copper, zinc, and imidazole coated poly‐ l ‐lactic acid nanofiber scaffolds

2019 ◽  
Author(s):  
M. D. Telgerd ◽  
Mohammad Sadeghinia ◽  
Gebremariam Birhanu ◽  
M. P. Daryasari ◽  
Ali Zandi‐Karimi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Lactic Acid ◽  
Osteogenic Differentiation ◽  
Metal Organic Framework ◽  
Nanofiber Scaffolds ◽  
Metal Organic ◽  
Copper Zinc ◽  
Organic Framework

scholarly journals Bimetallic AgPd/UiO-66 Hybrid Catalysts for Propylene Glycol Oxidation into Lactic Acid

Materials ◽  
2020 ◽  
Vol 13 (23) ◽  
pp. 5471
Author(s):  
Sergey Ten ◽  
Viktoriia V. Torbina ◽  
Vladimir I. Zaikovskii ◽  
Sergei A. Kulinich ◽  
Olga Vodyankina
Keyword(s):  
Lactic Acid ◽  
Propylene Glycol ◽  
External Surface ◽  
Pore Space ◽  
Metal Organic Framework ◽  
Acetonitrile Solution ◽  
Transition Electron Microscopy ◽  
Metal Organic ◽  
Temperature Programmed ◽  
Organic Framework

Different methods (the wetness impregnation of Ag and Pd precursors dissolved in water or acetonitrile solution, and the double solvent impregnation technique) were employed to immobilize Ag–Pd nanoparticles (NPs) into the pores of the microporous zirconium-based metal-organic framework known as UiO-66. The obtained materials were characterized by using nitrogen adsorption-desorption at −196 °C, powder X-ray diffraction, UV-Vis diffusion reflectance spectroscopy, and transition electron microscopy measurements. Special attention was paid to the acid and redox properties of the obtained materials, which were studied by using temperature-programmed desorption of ammonia (TPD-NH3) and temperature-programmed reduction (TPR-H2) methods. The use of a drying procedure prior to reduction was found to result in metallic NPs which, most likely, formed on the external surface and were larger than corresponding voids of the metal-organic framework. The formation of Ag–Pd alloy or monometallic Ag and Pd depended on the nature of both metal precursors and the impregnation solvent used. Catalytic activity of the AgPd/UiO-66 materials in propylene glycol oxidation was found to be a result of synergistic interaction between the components in AgPd alloyed NPs immobilized in the pore space and on the external surface of UiO-66. The key factor for consistent transformation of propylene glycol into lactic acid was the proximity between redox and acid-base species.

Baghdadite nanoparticle‐coated poly l ‐lactic acid (PLLA) ceramics scaffold improved osteogenic differentiation of adipose tissue‐derived mesenchymal stem cells

2019 ◽  
Vol 107 (6) ◽  
pp. 1284-1293 ◽  
Author(s):  
Zohreh Karimi ◽  
Ehsan Seyedjafari ◽  
Fatemeh Sadat Mahdavi ◽  
Seyed Mahmoud Hashemi ◽  
Arash Khojasteh ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Adipose Tissue ◽  
Lactic Acid ◽  
Osteogenic Differentiation

scholarly journals Osteogenic Differentiation of Pre-Conditioned Bone Marrow Mesenchymal Stem Cells with Nisin on the Modified Poly-L-Lactic-Acid Nanofibers

2021 ◽  
Author(s):  
Fariba Sadraei ◽  
Marzieh Ghollasi ◽  
Fatemeh Khakpai ◽  
Raheleh Halabian
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Cell Proliferation ◽  
Mesenchymal Stem Cells ◽  
Lactic Acid ◽  
Osteogenic Differentiation ◽  
Real Time ◽  
Real Time Pcr ◽  
Alizarin Red ◽  
Marrow Mesenchymal Stem Cells

Abstract Background: Human bone marrow-derived mesenchymal stem (MSCs) cells are undifferentiated cells with the self-renewing ability and multi-lineage differentiation beneficial for regenerative medicine. Nano scaffolds are novel materials employed in bone repair and regeneration. Nisin is a prebiotic that can increase stem cells’ life span and proliferation. This study attempted to provide a proper strategy for bone marrow mesenchymal stem cells differentiation into the Osteocytes on a Poly‐L‐lactic‐acid scaffold (PLLA) after pretreating with probiotic Nisin. Methods: MSC osteogenic differentiation was evaluated by measuring Calcium, Alkaline phosphatase, and quantitative tests such as Real-Time PCR, Acridine Orange, Alizarin Red, Von Kossa, and others. Results: The result of the MTT test showed that the optimal dose of Nisin probiotic for the MSCs’ preconditioning was 200 IU/mL on the 1st, 3rd, and 5th days of culture. Real-time PCR data indicated that the expression rate of ALP, Osteonectin, Osteocalcin, and Collagen I have increased in the presence of Nisin, while the RUNX-2 gene expression has decreased. Furthermore, the results of Alizarin Red and Von Kossa tests, as well as Scanning electron microscopy (SEM), revealed that the cell proliferation in the preconditioned samples with Nisin increased significantly. Conclusions: The study concluded that the cell proliferation and differentiation increased in samples pretreated with Nisin on the PLLA Nano scaffolds.

Aluminum based metal‐organic framework as water‐tolerant Lewis acid catalyst for selective dihydroxyacetone isomerization to lactic acid

ChemCatChem ◽  
2021 ◽  
Author(s):  
Mohammad Shahinur Rahaman ◽  
Sarttrawut Tulaphol ◽  
Kyle Mills ◽  
Ashten Molley ◽  
Md Anwar Hossain ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Lewis Acid ◽  
Metal Organic Framework ◽  
Acid Catalyst ◽  
Metal Organic ◽  
Lewis Acid Catalyst ◽  
Organic Framework

scholarly journals MIL-100(Fe)-catalyzed efficient conversion of hexoses to lactic acid

RSC Advances ◽  
2017 ◽  
Vol 7 (10) ◽  
pp. 5621-5627 ◽  
Author(s):  
Shan Huang ◽  
Kai-Li Yang ◽  
Xiao-Fang Liu ◽  
Hu Pan ◽  
Heng Zhang ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Metal Organic Framework ◽  
Catalytic Transformation ◽  
Efficient Conversion ◽  
Hexose Sugars ◽  
Metal Organic ◽  
First Time ◽  
Organic Framework

Lewis acidic metal–organic framework (MOF), MIL-100(Fe), was for the first time demonstrated to be efficient for the catalytic transformation of hexose sugars into lactic acid.

Flexible fibrous membrane based on copper(II) metal-organic framework/poly(lactic acid) composites with superior antibacterial performance

2021 ◽  
Author(s):  
Zhao Liu ◽  
Junwei Ye ◽  
Abdul Rauf ◽  
Siqi Zhang ◽  
Guangyao Wang ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Metal Organic Framework ◽  
Three Dimensional ◽  
Fibrous Membrane ◽  
Poly Lactic Acid ◽  
Healthcare Applications ◽  
Antibacterial Efficiency ◽  
Antibacterial Performance ◽  
Metal Organic ◽  
Organic Framework

Flexible antibacterial fibrous membrane employing high antibacterial efficiency has great potential in healthcare applications. Herein, a three-dimensional copper(II) metal-organic framework [Cu2(CA)(H2O)2, Cu-MOF-1] and poly(lactic acid) (PLA) composite fibrous membrane was...

Poly(L -lactic acid) metal organic framework composites: optical, thermal and mechanical properties

2011 ◽  
Vol 61 (1) ◽  
pp. 30-37 ◽  
Author(s):  
Dhayalan Elangovan ◽  
Isinay E Yuzay ◽  
Susan E M Selke ◽  
Rafael Auras
Keyword(s):  
Mechanical Properties ◽  
Lactic Acid ◽  
Metal Organic Framework ◽  
Thermal And Mechanical Properties ◽  
Metal Organic ◽  
Organic Framework
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